Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mototaka Matsuyama"'
Publikováno v:
Biological and Pharmaceutical Bulletin. 37:1641-1649
Chondroitin sulfate-glycyl-prednisolone conjugate (CS-GP) was previously demonstrated to exhibit superior anti-arthritic effects compared to prednisolone (PD) alone. In this study, CS-GP was examined for its pharmacokinetic features and tropism for i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc3f15b90bb7c65e0e8b2266a5d94cc
https://doi.org/10.1248/bpb.b14-00390
https://doi.org/10.1248/bpb.b14-00390
Publikováno v:
International Journal of Pharmaceutics. 456:113-120
A conjugate between chondroitin sulfate (CS) and glycyl-prednisolone (GP), named CS-GP, was prepared as a delivery system for the treatment of rheumatoid arthritis by referring to the previous report. CS-GP conjugates with different prednisolone (PD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d47a84ff68bfa6d589ace2b5cbddf6b
https://doi.org/10.1016/j.ijpharm.2013.08.007
https://doi.org/10.1016/j.ijpharm.2013.08.007
Autor:
Hiraku Onishi, Mototaka Matsuyama
Publikováno v:
Chemical and Pharmaceutical Bulletin. 61:902-912
A conjugate between prednisolone (PD) and chondroitin sulfate (CS) with glycine as a linker was prepared in order to obtain an effective macromolecular prodrug against inflammatory disease, especially rheumatoid arthritis. First, PD was converted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::242c8e46989874d1d1ce473763dee679
https://doi.org/10.1248/cpb.c13-00189
https://doi.org/10.1248/cpb.c13-00189
Autor:
Takatoshi Nagate, Yoshihisa Toda, Yukiko Kondo, Takayuki Seki, Yoko Furukawa, Mototaka Matsuyama, Nobuko Hosokawa, Takanobu Sakurai, Shigeru Murakami, Kazuhiro Nagata, Eiji Munetomo
Publikováno v:
Atherosclerosis. 157:361-368
Heat shock protein (HSP) 47, a collagen-specific molecular chaperone, is thought to be essential for the proper processing and secretion of procollagen molecules. We investigated the time course and localization of HSP47 and collagen expression after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24ead2ba8404c3b811b1a13518e1c9d
https://doi.org/10.1016/s0021-9150(00)00743-7
https://doi.org/10.1016/s0021-9150(00)00743-7
Autor:
Hiraku, Onishi, Mototaka, Matsuyama
Publikováno v:
Chemicalpharmaceutical bulletin. 61(9)
A conjugate between prednisolone (PD) and chondroitin sulfate (CS) with glycine as a linker was prepared in order to obtain an effective macromolecular prodrug against inflammatory disease, especially rheumatoid arthritis. First, PD was converted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14b790323f34b1b82bc6150b9ed138ac
https://pubmed.ncbi.nlm.nih.gov/23995354
https://pubmed.ncbi.nlm.nih.gov/23995354
Publikováno v:
FEBS letters. 394(1)
Gene expression of human immunodeficiency virus (HIV) depends on a host cellular transcription factors including nuclear factor-kappaB (NF-kappaB). The involvement of reactive oxygen intermediates (ROI) has been implicated as intracellular messengers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea2f0c54c39c7667469f7d89427238c
https://pubmed.ncbi.nlm.nih.gov/8925935
https://pubmed.ncbi.nlm.nih.gov/8925935
Publikováno v:
Chemicalpharmaceutical bulletin. 35(1)
Commercially available Cu, Zn superoxide dismutase (SOD) from bovine erythrocytes was purified. Purified SOD was incubated with 1 M glucose at 37 °C for 14d under sterile conditions. Nonezymatic addition of glucose to SOD molecules increased linearl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667a6fd47ba157faad06d985c134e6ce
https://pubmed.ncbi.nlm.nih.gov/3594660
https://pubmed.ncbi.nlm.nih.gov/3594660