Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Motoshi Nagao"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract In the majority of spinal cord injury (SCI) patients, spasticity develops in the subacute phase and chronically persists with muscle hypertonia. Among various pathological conditions underlying spasticity, upregulated expression of 5-HT rece
Externí odkaz:
https://doaj.org/article/f69cb93e96a341c7a8c62d60adc9ad1c
Autor:
Youngjae Ryu, Takahiro Maekawa, Daisuke Yoshino, Naoyoshi Sakitani, Atsushi Takashima, Takenobu Inoue, Jun Suzurikawa, Jun Toyohara, Tetsuro Tago, Michiru Makuuchi, Naoki Fujita, Keisuke Sawada, Shuhei Murase, Masashi Watanave, Hirokazu Hirai, Takamasa Sakai, Yuki Yoshikawa, Toru Ogata, Masahiro Shinohara, Motoshi Nagao, Yasuhiro Sawada
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: Mechanical forces are known to be involved in various biological processes. However, it remains unclear whether brain functions are mechanically regulated under physiological conditions. Here, we demonstrate that treadmill running and passiv
Externí odkaz:
https://doaj.org/article/5cfc7928387b4f60a72c305c1157419d
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Astrocytes in the brain are derived from neural precursor cells (NPCs). Here, Motoshi Nagao and colleagues show that the transcription repressor Zbtb20 regulates astrocyte specification in the mouse neocortex.
Externí odkaz:
https://doaj.org/article/6ac7882b244849bc8076bb3d9ddaddd7
Autor:
Youngjae Ryu, Toru Ogata, Motoshi Nagao, Taku Kitamura, Kazuhito Morioka, Yoshinori Ichihara, Toru Doi, Yasuhiro Sawada, Masami Akai, Ryohei Nishimura, Naoki Fujita
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171937 (2017)
Spasticity is a frequent chronic complication in individuals with spinal cord injury (SCI). However, the severity of spasticity varies in patients with SCI. Therefore, an evaluation method is needed to determine the severity of spasticity. We used a
Externí odkaz:
https://doaj.org/article/2c6cc97d371e4b9fbbe3e70a78009143
Autor:
Takahiro Maekawa, Naoyoshi Sakitani, Youngjae Ryu, Atsushi Takashima, Shuhei Murase, Julius Fink, Motoshi Nagao, Toru Ogata, Masahiro Shinohara, Yasuhiro Sawada
Publikováno v:
Journal of visualized experiments : JoVE. (185)
Exercise is widely recognized as effective for various diseases and physical disorders, including those related to brain dysfunction. However, molecular mechanisms behind the beneficial effects of exercise are poorly understood. Many physical workout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c84b9d650759753f75e8bba08189294
https://pubmed.ncbi.nlm.nih.gov/35938802
https://pubmed.ncbi.nlm.nih.gov/35938802
Autor:
Naoyoshi Sakitani, Takahiro Maekawa, Daisuke Yoshino, Kouji Takano, Keisuke Shinohara, Takuya Kishi, Koji Tomiyasu, Toru Ogata, Hirotsugu Tsuchimochi, Shigeyoshi Saito, Kohzoh Yoshino, Kenichi Funamoto, Masahiro Shinohara, Motoshi Nagao, Yasuhiro Sawada
Publikováno v:
Journal of Hypertension. 41:e370
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d8b1b2db8abefd5bda876b8d04e7f89
https://doi.org/10.1097/01.hjh.0000916568.22302.f2
https://doi.org/10.1097/01.hjh.0000916568.22302.f2
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
In the majority of spinal cord injury (SCI) patients, spasticity develops in the subacute phase and chronically persists with muscle hypertonia. Among various pathological conditions underlying spasticity, upregulated expression of 5-HT receptors (5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747eed38e97ab277abd904f5ab347bbe
http://europepmc.org/articles/PMC8007832
http://europepmc.org/articles/PMC8007832
Autor:
Shuhei Murase, Naoyoshi Sakitani, Takahiro Maekawa, Daisuke Yoshino, Kouji Takano, Ayumu Konno, Hirokazu Hirai, Taku Saito, Sakae Tanaka, Keisuke Shinohara, Takuya Kishi, Yuki Yoshikawa, Takamasa Sakai, Makoto Ayaori, Hirohiko Inanami, Koji Tomiyasu, Atsushi Takashima, Toru Ogata, Hirotsugu Tsuchimochi, Shinya Sato, Shigeyoshi Saito, Kohzoh Yoshino, Yuiko Matsuura, Kenichi Funamoto, Hiroki Ochi, Masahiro Shinohara, Motoshi Nagao, Yasuhiro Sawada
Nervous cell functions are known to be physiologically regulated by mechanical factors in the brain. However, it remains unclear whether mechanical interventions can modulate the pathophysiological processes underlying brain-related disorders and mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd3f6ae420234aac676344569e96ad70
https://doi.org/10.1101/2020.09.21.305706
https://doi.org/10.1101/2020.09.21.305706
Autor:
Jun Toyohara, Tetsuro Tago, Takamasa Sakai, Keisuke Sawada, Takenobu Inoue, Hirokazu Hirai, Naoyoshi Sakitani, Motoshi Nagao, Michiru Makuuchi, Masahiro Shinohara, Atsushi Takashima, Takahiro Maekawa, Naoki Fujita, Masashi Watanave, Daisuke Yoshino, Shuhei Murase, Jun Suzurikawa, Yuki Yoshikawa, Toru Ogata, Youngjae Ryu, Yasuhiro Sawada
Publikováno v:
iScience, Vol 23, Iss 2, Pp-(2020)
iScience
iScience
Summary Mechanical forces are known to be involved in various biological processes. However, it remains unclear whether brain functions are mechanically regulated under physiological conditions. Here, we demonstrate that treadmill running and passive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4800f36059024a95038325c87807681a
http://www.sciencedirect.com/science/article/pii/S2589004220300584
http://www.sciencedirect.com/science/article/pii/S2589004220300584
Autor:
Atsushi Takashima, Keisuke Sawada, Yoshinori Ichihara, Motoshi Nagao, Karina Kouzaki, Toru Ogata, Takahiro Maekawa, Noriaki Kawanishi, Koichi Nakazato, Hideki Nakamoto, Ichiro Harada, Youngjae Ryu, Yasuhiro Sawada, Michiru Makuuchi, Shunsuke Kawamura, Daisuke Yoshino, Katsuhiko Suzuki, Naoyoshi Sakitani, Masakuni Tokunaga, Kumiko Saitou, Taku Saito
Publikováno v:
Clinical Science. 132:2147-2161
Physical inactivity gives rise to numerous diseases and organismal dysfunctions, particularly those related to aging. Musculoskeletal disorders including muscle atrophy, which can result from a sedentary lifestyle, aggravate locomotive malfunction an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f50e05f6fec359840e54ee93d5becb2c
https://doi.org/10.1042/cs20180432
https://doi.org/10.1042/cs20180432