Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Motoshi Komatsubara"'
Autor:
Eisaku Morimoto, Kenichi Inagaki, Motoshi Komatsubara, Tomohiro Terasaka, Yoshihiko Itoh, Satoshi Fujisawa, Erika Sasaki, Yuki Nishiyama, Takayuki Hara, Jun Wada
Publikováno v:
Journal of the Endocrine Society. 6
Pheochromocytomas and paragangliomas (PPGLs) are classified into 3 major categories with distinct driver genes: pseudohypoxia, kinase signaling, and Wnt-altered subtypes. PPGLs in the Wnt-altered subtype are sporadic and tend to be aggressive with me
Publikováno v:
Journal of the Endocrine Society
Incretins, such as gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), are metabolic hormones secreted from the intestine to stimulate insulin secretion from the pancreatic β cells. Dipeptidyl peptidase-4 (DPP-4) inhibitors, as
Autor:
Kiichiro Ninomiya, Naohiro Oda, Masahiro Tabata, Mitsune Tanimoto, Kenichi Inagaki, Nobuaki Miyahara, Katsuyuki Kiura, Daisuke Minami, Motoshi Komatsubara, Arihiko Kanehiro
Publikováno v:
Internal Medicine
We herein report the case of a 44-year-old man who was diagnosed with pneumocystis pneumonia (PCP) concomitant with ectopic adrenocorticotropic hormone (ACTH) syndrome, which had been caused by a large cell neuroendocrine carcinoma of the thymus. Che
Autor:
Motoshi Komatsubara, Naoko Tsukamoto-Yamauchi, Takayuki Hara, Fumio Otsuka, Nahoko Iwata, Kenichi Inagaki, Kishio Toma, Jun Wada, Takeshi Hosoya
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 165:182-189
Melatonin is functionally involved in the control of circadian rhythm and hormonal secretion. In the present study, we investigated the roles of melatonin in the interaction of catecholamine synthesis with adrenocortical steroids by focusing on bone
Autor:
Kanako Ogura-Ochi, Takayuki Hara, Kenichi Inagaki, Satoshi Fujisawa, Naoko Tsukamoto-Yamauchi, Motoshi Komatsubara, Jun Wada, Kishio Toma, Fumio Otsuka
Publikováno v:
Journal of the Endocrine Society
Orexin A and B, are neuropeptides that are mainly produced in the hypothalamus. Orexins play important roles in food intake and in regulation of sleep and arousal. In the peripheral tissues, orexins also regulate various endocrine activities includin
Autor:
Naoko Tsukamoto-Yamauchi, Takahiro Nada, Nahoko Iwata, Satoshi Fujisawa, Jun Wada, Motoshi Komatsubara, Fumio Otsuka
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4553, p 4553 (2021)
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4553, p 4553 (2021)
Orexin is expressed mainly in the hypothalamus and is known to activate the hypothalamic–pituitary–adrenal (HPA) axis that is involved in various stress responses and its resilience. However, the effects of orexin on the endocrine function of pit
Autor:
Naoko Tsukamoto-Yamauchi, Motoshi Komatsubara, Kishio Toma, Fumio Otsuka, Kenichi Inagaki, Tomohiro Terasaka, Hirofumi Makino, Kohei Oguni
Publikováno v:
Peptides. 76:96-101
The effects of somatostatin analogs and roles of BMP-6 in the regulation of luteinizing hormone (LH) secretion were investigated using mouse gonadotrope LβT2 cells. LH mRNA expression and LH secretion induced by GnRH were suppressed by treatments wi
Autor:
Satoshi Fujisawa, Motoshi Komatsubara, Fumio Otsuka, Naoko Tsukamoto-Yamauchi, Jun Wada, Kanako Ogura-Ochi, Kishio Toma, Kenichi Inagaki
Publikováno v:
Peptides. 113
The impact of orexins on anterior pituitary function has yet to be clarified. We studied the effects of orexin A and its interaction with the bone morphogenetic protein (BMP) system on the regulatory role of prolactin synthesis using rat lactotrope G
Regulatory role of melatonin and BMP-4 in prolactin production by rat pituitary lactotrope GH3 cells
Autor:
Kanako Ogura-Ochi, Motoshi Komatsubara, Jun Wada, Fumio Otsuka, Kenichi Inagaki, Naoko Tsukamoto-Yamauchi, Nahoko Iwata, Yuki Nishiyama, Satoshi Fujisawa
Publikováno v:
Peptides. 94
The effects of melatonin on prolactin production and its regulatory mechanism remain uncertain. We investigated the regulatory role of melatonin in prolactin production using rat pituitary lactotrope GH3 cells by focusing on the bone morphogenetic pr
Autor:
Kenichi Inagaki, Tomohiro Terasaka, Fumio Otsuka, Ryota Nagao, Nahoko Iwata, Takayuki Katsuyama, Kosuke Kimura, Motoshi Komatsubara
Publikováno v:
Journal of Clinical Medicine; Volume 6; Issue 1; Pages: 6
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 6, Iss 1, p 6 (2017)
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 6, Iss 1, p 6 (2017)
Osteoblasts undergo differentiation in response to various factors, including growth factors and steroids. Bone mass is diminished in androgen- and/or growth hormone (GH)-deficient patients. However the functional relationship between androgen and GH