Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Motoshi Kaya"'
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Skeletal muscle myosin forms large ensembles to generate force against high loads. Using optical tweezers and simulation Kayaet al. provide experimental evidence for cooperative force generation, and describe how the molecular properties of skeletal
Externí odkaz:
https://doaj.org/article/ce3987606aff4fb0bbb5abd6897b3bf8
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173415 (2017)
Frogs' outstanding jumping ability has been associated with a high power output from the leg extensor muscles. Two main theories have emerged to explain the high power output of the frog leg extensor muscles, either (i) the contractile conditions of
Externí odkaz:
https://doaj.org/article/a3461f7ac43e47acb5c93dae435d7aa9
Publikováno v:
Proc Natl Acad Sci U S A
Changes in the molecular properties of cardiac myosin strongly affect the interactions of myosin with actin that result in cardiac contraction and relaxation. However, it remains unclear how myosin molecules work together in cardiac myofilaments and
Autor:
Motoshi Kaya
Publikováno v:
Seibutsu Butsuri. 59:241-247
Publikováno v:
Biophysical Journal. 115:1981-1992
Dimeric motor proteins, kinesin-1, cytoplasmic dynein-1, and myosin-V, move stepwise along microtubules and actin filaments with a regular step size. The motors take backward as well as forward steps. The step ratio r and dwell time τ, which are the
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
A power stroke of dynein is thought to be responsible for the stepping of dimeric dynein. However, the actual size of the displacement driven by a power stroke has not been directly measured. Here, the displacements of single-headed cytoplasmic dynei
Autor:
Motoshi Kaya
Publikováno v:
Minorities and Small Numbers from Molecules to Organisms in Biology ISBN: 9789811320828
Many types of proteins are at work inside our bodies. These proteins include so-called molecular motors, which harness chemical energy from sources such as ATP to generate force and torque. For example, molecular motors called myosins generate force
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1718d73d897e39bfd4516ceab078b194
https://doi.org/10.1007/978-981-13-2083-5_11
https://doi.org/10.1007/978-981-13-2083-5_11
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature Communications
In contrast to processive molecular motors, skeletal myosins form a large motor ensemble for contraction of muscles against high loads. Despite numerous information on the molecular properties of skeletal myosin, its ensemble effects on collective fo
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173415 (2017)
PLoS ONE
PLoS ONE
Frogs’ outstanding jumping ability has been associated with a high power output from the leg extensor muscles. Two main theories have emerged to explain the high power output of the frog leg extensor muscles, either (i) the contractile conditions o
Autor:
Hideo Higuchi, Motoshi Kaya
Publikováno v:
Cellular and Molecular Life Sciences. 70:4275-4292
In muscles, the arrays of skeletal myosin molecules interact with actin filaments and continuously generate force at various contraction speeds. Therefore, it is crucial for myosin molecules to generate force collectively and minimize the interferenc