Zobrazeno 1 - 10
of 377
pro vyhledávání: '"Motor incoordination"'
Autor:
Marta Llansola, Yaiza M. Arenas, María Sancho-Alonso, Gergana Mincheva, Andrea Palomares-Rodriguez, Magnus Doverskog, Paula Izquierdo-Altarejos, Vicente Felipo
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Enhanced GABAergic neurotransmission contributes to impairment of motor coordination and gait and of cognitive function in different pathologies, including hyperammonemia and hepatic encephalopathy. Neuroinflammation is a main contributor to enhancem
Externí odkaz:
https://doaj.org/article/46267b8a981c4fa7ae2850062468ab10
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-18 (2023)
Abstract The 14-3-3 protein family with seven isoforms found in mammals is widely expressed in the brain and plays various roles in cellular processes. Several studies have reported that 14-3-3γ, one of the 14-3-3 protein isoforms, is associated wit
Externí odkaz:
https://doaj.org/article/8dd6f0e19f084685bf1366afb83c43ba
Akademický článek
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Autor:
Lee-Yuan Liu-Chen, Peng Huang
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Kappa opioid receptor (KOR) agonists are potentially useful as analgesic and anti-pruritic agents, for prevention and treatment of substance use disorders, and for treatment of demyelinating diseases. However, side effects of KOR agonists, including
Externí odkaz:
https://doaj.org/article/703df32d492a45cc95efba73c007d405
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Selective kappa opioid receptor (KOR) agonists are promising antipruritic agents and analgesics. However, clinical development of KOR agonists has been limited by side effects, including psychotomimetic effects, dysphoria, and sedation, except for na
Externí odkaz:
https://doaj.org/article/b6b3def666d547b68d79b7c05e40fed6
Akademický článek
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Akademický článek
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Autor:
María Gómez-Ruiz, Carmen Rodríguez-Cueto, Eva Luna-Piñel, Mariluz Hernández-Gálvez, Javier Fernández-Ruiz
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Spinocerebellar ataxias (SCAs) are a group of hereditary and progressive neurological disorders characterized by a loss of balance and motor coordination typically associated with cerebellar atrophy. The most prevalent SCA types are all polyQ disorde
Externí odkaz:
https://doaj.org/article/49477ae53f414002978969ec472faf8c
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol. 20 No. 6 (2021); 1193-1198
Purpose: To evaluate the effect of Mucuna pruriens on ischemia-induced motor incoordination. Methods: Male Wistar rats were used in this study were divided into eight groups of six rats each. The bilateral common carotid artery (BCA) was occluded to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92f06ddfb6eed5a5fe0f5796025eb32
https://doi.org/10.4314/tjpr.v20i6.14
https://doi.org/10.4314/tjpr.v20i6.14
Autor:
Eduardo Rivadeneyra-Domínguez, José Eduardo Pérez-Pérez, Alma Vázquez-Luna, Rafael Díaz-Sobac, Juan Francisco Rodríguez-Landa
Publikováno v:
Toxins, Vol 12, Iss 11, p 708 (2020)
Cassava (Manihot esculenta Crantz) is a plant that contains neurotoxins such as linamarin and lotaustraline. Its long-term consumption is associated with neuronal damage and contributes to the development of motor impairment in humans and rats. We in
Externí odkaz:
https://doaj.org/article/5a6db5ceffa240e6a143946e10b3e143