Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Motoo Osaka"'
Autor:
Hoai-Nga Thi Nguyen, Cat-Khanh Vuong, Mizuho Fukushige, Momoko Usuda, Liora Kaho Takagi, Toshiharu Yamashita, Mana Obata-Yasuoka, Hiromi Hamada, Motoo Osaka, Toru Tsukada, Yuji Hiramatsu, Osamu Ohneda
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionSARS-CoV-2 infection increases the risk of worse outcomes in cancer patients, including those with breast cancer. Our previous study reported that the SARS-CoV-2 membrane protein (M-protein) promotes the malignant transformation of triple
Externí odkaz:
https://doaj.org/article/7e9c45043bd74ee7a44783f6b65c092b
Autor:
Yun-Hsuan Chang, Cat-Khanh Vuong, Nhat-Hoang Ngo, Toshiharu Yamashita, Xiucai Ye, Yasunori Futamura, Mizuho Fukushige, Mana Obata-Yasuoka, Hiromi Hamada, Motoo Osaka, Yuji Hiramatsu, Tetsuya Sakurai, Osamu Ohneda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Triple negative breast cancer (TNBC) is associated with worse outcomes and results in high mortality; therefore, great efforts are required to find effective treatment. In the present study, we suggested a novel strategy to treat TNBC using
Externí odkaz:
https://doaj.org/article/ab31886cf36f46bbba0e0c1d2e6ae2c4
Autor:
Nhat-Hoang Ngo, Yun-Hsuan Chang, Cat-Khanh Vuong, Toshiharu Yamashita, Mana Obata-Yasuoka, Hiromi Hamada, Motoo Osaka, Yuji Hiramatsu, Osamu Ohneda
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Introduction: The therapeutic effects of endothelial progenitor cells (EPC) in neovascularization have been suggested; however, to date, few studies have been conducted on the ability of EPC-derived extracellular vesicles (EV) to rescue the ischemic
Externí odkaz:
https://doaj.org/article/ac3fb8d3cea145f7b4a246fa43b2782b
Autor:
Vuong Cat Khanh, Hiromi Hamada, Motoo Osaka, Yun Hsuan Chang, Toshiharu Yamashita, Mana Obata-Yasuoka, Osamu Ohneda, Ngo Nhat Hoang, Mizuho Fukushige, Yuji Hiramatsu
Publikováno v:
Stem Cells and Development
Cytokine storm is recognized as one of the factors contributing to organ failures and mortality in patients with COVID-19. Due to chronic inflammation, COVID-19 patients with diabetes mellitus (DM) or renal disease (RD) have more severe symptoms and
Autor:
Yun-Hsuan Chang, Nhat-Hoang Ngo, Cat-Khanh Vuong, Toshiharu Yamashita, Motoo Osaka, Yuji Hiramatsu, Osamu Ohneda
Publikováno v:
Stem cells and development. 31(21-22)
Triple-negative breast cancer (TNBC) is a highly aggressive and invasive type of breast cancer. In addition, type 2 diabetes mellitus (T2DM) is recognized as a risk factor for cancer metastasis, which is associated with mortality in patients with bre
Autor:
Motoo Osaka, Hiromi Yanagisawa, Tomonari Shimoda, Yoshito Yamashiro, Huynh Thuy Hang, Bui Quoc Thang, Seung Jae Shin, Hiroaki Sakamoto, Yuji Hiramatsu
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:1905-1917
Objective: Remodeling of the extracellular matrix plays a vital role in cardiovascular diseases. Using a mouse model of postnatal ascending aortic aneurysms (termed Fbln4 SMKO ), we have reported that abnormal mechanosensing led to aneurysm formation
Publikováno v:
JTCVS Techniques
Autor:
Nanami Imai, Yuichiro Kaminishi, Toru Tsukada, Motoo Osaka, Hiroaki Sakamoto, Bryan James Mathis, Yasuyuki Suzuki, Yuji Hiramatsu
Publikováno v:
General thoracic and cardiovascular surgery. 70(3)
Reports of early and catastrophic acute structural valve deterioration (SVD) in Trifecta valve (Abbott, St Paul, MN, USA) with multiple leaflet detachment are rare. We encountered two cases of early SVD in Trifecta valve with tears on two leaflets. B
Autor:
Motoo Osaka, Ryuhei Yamamoto, Kazuhumi Suzuki, Tomomi Nakajima, Toru Tsukada, Bryan Mathis, Hiroaki Sakamoto, Yuji Hiramatsu
Publikováno v:
General thoracic and cardiovascular surgery. 70(4)
Median sternotomy near an existing tracheostoma risks deep sternal wound infection after cardiac surgery. We present herein a case of acute type A aortic dissection in a patient with a permanent tracheostoma after laryngectomy. Total arch replacement
Autor:
Yuji Hiramatsu, Motoo Osaka, Kana Moriguchi, Mizuho Fukushige, Vuong Cat Khanh, Toshiharu Yamashita, Osamu Ohneda
Publikováno v:
Stem cells and development. 29(21)
Cancer metastasis is the leading cause of mortality among breast cancer patients. Type 2 diabetes mellitus (T2DM) has been suggested as a risk factor of breast cancer; however, whether or not T2DM is associated with breast tumor metastasis remains un