Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Motonari Kondo"'
Publikováno v:
International Archives of Otorhinolaryngology, Vol 25, Iss 03, Pp e416-e420 (2021)
Introduction Chronic rhinosinusitis (CRS) is commonly classified based on the presence or absence of nasal polyps (NPs). Eosinophil infiltration is observed in NPs of patients in Western countries. In contrast, in East Asian countries, including Japa
Externí odkaz:
https://doaj.org/article/7f342321625f40e3a185837b69154cde
Publikováno v:
Data in Brief, Vol 17, Iss , Pp 1180-1183 (2018)
The data presented here are related to the research article entitled “Loss of Eed leads to lineage instability and increased CD8 expression of mouse CD4+ T cells upon TGFβ signaling” [1]. The cited research article investigates the molecular mec
Externí odkaz:
https://doaj.org/article/6086886cbf8f44e7a0c2960ba598b61a
Autor:
Yuriko Tanaka, Mayu Onozato, Tetuo Mikami, Terumi Kohwi-Shigematsu, Takeshi Fukushima, Motonari Kondo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 10125 (2021)
Sjögren’s syndrome (SS) is a chronic autoimmune disease characterized by dysfunction of salivary and lacrimal glands, resulting in xerostomia (dry mouth) and keratoconjunctivitis sicca (dry eyes). Autoantibodies, such as anti-SSA and anti-SSB anti
Externí odkaz:
https://doaj.org/article/80fd915b3c98485c8311bd45c089a767
Autor:
Mayu Onozato, Yuriko Tanaka, Michitsune Arita, Tatsuya Sakamoto, Hideaki Ichiba, Kiyomi Sadamoto, Motonari Kondo, Takeshi Fukushima
Publikováno v:
Practical Laboratory Medicine, Vol 12, Iss , Pp - (2018)
Objectives: Amino acid levels in serum or plasma are used for early detection and diagnosis of several diseases. The objective of this study was to analyze amino acid levels in serum exosomes, which have not been previously reported. Design and metho
Externí odkaz:
https://doaj.org/article/e2a5f77dbf834503971396e368935ee4
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 506 (2020)
Hypoxic cellular proliferation is a common feature of tumor cells and is associated with tumor progression. Therefore, the inhibition of hypoxic cellular proliferation is expected to regulate malignancy processes. Licochalcone A (LicA) is known to sh
Externí odkaz:
https://doaj.org/article/05053fb9ebe9494f9636be9d490f681e
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Interleukin-17 (IL-17) induces the production of granulocyte colony-stimulating factor (G-CSF) and chemokines such as CXCL1 and CXCL2 and is a cytokine that acts as an inflammation mediator. During infection, IL-17 is needed to eliminate extracellula
Externí odkaz:
https://doaj.org/article/af541d8fa4534d5694b08b35bb304ce8
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2522 (2018)
Interleukin-7 (IL-7) is essential for lymphocyte development. To identify the functional subdomains in the cytoplasmic tail of the IL-7 receptor (IL-7R) α chain, here, we constructed a series of IL-7Rα deletion mutants. We found that IL-7Rα-defici
Externí odkaz:
https://doaj.org/article/e3c06a3469fe4b0bbdac25bf46137a97
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 819 (2018)
The adaptive immune system involves antigen-specific host defense mechanisms mediated by T and B cells. In particular, CD4+ T cells play a central role in the elimination of pathogens. Immunological tolerance in the thymus regulates T lymphocytes to
Externí odkaz:
https://doaj.org/article/1f6112ecdf3f41ce9d03ab3f4d7d1e8c
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28350 (2011)
Myelodysplastic syndromes/myeloproliferative neoplasms (MDS/MPNs) are a group of myeloid neoplasms in which abnormal activation of the Ras signaling pathway is commonly observed. The PI3K/Akt pathway is a known target of Ras; however, activation of t
Externí odkaz:
https://doaj.org/article/ddbed8c0f4a54e10aa77d2d80dee599b
Publikováno v:
The Journal of Immunology.
Double-positive thymocytes that have passed positive selection migrate from the cortex to the medulla, where negative selection and the development of thymic regulatory T cells (tTregs) take place. Medullary thymic epithelial cells (mTECs) play impor