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Interleukin 1 Upregulates Ovarian Prostaglandin Endoperoxide Synthase-2 Expression: Evidence for Prostaglandin-Dependent/Ceramide-Independent Transcriptional Stimulation and for Message Stabilization1

Autor: Daniel J. Sussman, Eli Y. Adashi, Juichiro Saito, Hiroaki Negishi, Motomu Ando, Gretchen J. King

Publikováno v: Biology of Reproduction. 65:1759-1765

We have recently documented a marked dependence of ovarian prostaglandin endoperoxide synthase (PGS)-2 transcripts, proteins, and activity on interleukin (IL) 1, a putative intermediary in the ovulatory cascade. The purpose of the present study was t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::562680fa00429b5769b10e9279a63547
https://doi.org/10.1095/biolreprod65.6.1759

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Periovulatory and Interleukin (IL)-1—Dependent Reglation of IL-6 in the Immature Rat Ovary: A Specific IL-1 Receptor-Mediated Eicosanoid-Dependent Effect

Autor: Eli Y. Adashi, Motomu Ando, Ki Wook Chung

Publikováno v: Journal of the Society for Gynecologic Investigation. 7:301-308

Interleukin (IL)-6, traditionally an IL-1—induced immune regulator, is nevertheless synthesized by a variety of tissues including the ovary. The purposes of this communication were to assess the ovarian expression of IL-6, examine its cyclic variat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::006ba5008fb104576d4fb777949d9429
https://doi.org/10.1177/107155760000700506

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Periovulatory and Interleukin-1β-Dependent Up-Regulation of Intraovarian Vascular Endothelial Growth Factor (VEGF) in the Rat: Potential Role for VEGF in the Promotion of Periovulatory Angiogenesis and Vascular Permeability

Autor: Laurence C. Udoff, Motomu Ando, Diran Chamoun, Eli Y. Adashi, Eliahu Levitas, Carol E. Resnick

Publikováno v: Journal of the Society for Gynecologic Investigation. 7:51-60

Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen and permeability factor the role of which in ovarian angiogenesis has been the subject of increasing interest. It was the objective of this communication to explore the possibil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63444cd189ce4536374ae63bf06369f9
https://doi.org/10.1177/107155760000700108

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Ovarian Interleukin-1 Receptor Antagonist in Rats: Gene Expression, Cellular Localization, Cyclic Variation, and Hormonal Regulation of a Potential Determinant of Interleukin-1 Action1

Autor: Eli Y. Adashi, Kristina Ruutiainen-Altman, Barry W. Donesky, Richard M. Rohan, Shahar Kol, Izhar Ben-Shlomo, Motomu Ando, Minoru Irahara

Publikováno v: Biology of Reproduction. 61:274-282

It is hypothesized that the intraovarian interleukin (IL)-1 system plays a prominent role in the regulation of follicular development and ovulation. A central component of the intraovarian IL-1 system is the IL-1 receptor antagonist (IL-1RA), a prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4e8e7f376c37ee2a6e2291e43109c86
https://doi.org/10.1095/biolreprod61.1.274

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Functional Role of Arg-Gly-Asp (RGD)-Binding Sites on β1 Integrin in Embryo Implantation Using Mouse Blastocysts and Human Decidua1

Autor: Motomu Ando, Hideki Hanashi, Ken Sakai, Yukio Nakamura, Shigetatsu Shiokawa, Shinya Nagamatsu, Hiroki Sawa, Yasunori Yoshimura

Publikováno v: Biology of Reproduction. 60:1468-1474

Amino acid residues 140-164 of integrin beta1 comprise an Arg-Gly-Asp (RGD) cross-linking region. The present study was undertaken to study the role of the RGD cross-linking region of integrin beta1 subunit in embryo implantation. Decidual cells atta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ee0d52c40ae51dc7c9e52b4134e351a
https://doi.org/10.1095/biolreprod60.6.1468

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Glucocorticoid Receptor-Mediated Post-Ceramide Inhibition of the Interleukin-1β-Dependent Induction of Ovarian Prostaglandin Endoperoxide Synthase-2 in Rats1

Autor: Motomu Ando, Eli Y. Adashi, Jean Sirois, Minoru Irahara, Juichiro Saito

Publikováno v: Biology of Reproduction. 60:946-953

Ovulation may constitute a cyclic, inflammatory-like process, wherein interleukin (IL)-1 induction and increased biosynthesis of prostanoids may feature prominently. In excess, glucocorticoids, potent anti-inflammatory agents, may exert an antiovulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9afb462f2815a4af36326037244c8ab7
https://doi.org/10.1095/biolreprod60.4.946

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Rat Ovarian Prostaglandin Endoperoxide Synthase-1 and -2: Periovulatory Expression of Granulosa Cell-Based Interleukin-1-Dependent Enzymes1

Autor: Kristiina Ruutiainen-Altman, Donna W. Payne, Shahar Kol, Ehud Kokia, Motomu Ando, Eli Y. Adashi, Jean Sirois, Richard M. Rohan

Publikováno v: Endocrinology. 139:2501-2508

This laboratory has previously shown that interleukin-1 (IL-1), a putative intermediary in the ovulatory process, is capable of up-regulating PG biosynthesis by cultured whole ovarian dispersates from immature rats. In part, this phenomenon was attri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b982f8152f00329e30a505d92fe7373e
https://doi.org/10.1210/endo.139.5.5988

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Ovarian Expression, Cellular Localization, and Hormonal Regulation of Rat Secretory Phospholipase A2: Increased Expression by Interleukin-1 and by Gonadotropins1

Autor: Eli Y. Adashi, Kristiina Ruutiainen Altman, Shahar Kol, Lechoslaw T. Putowski, Richard M. Rohan, Motomu Ando, Izhar Ben-Shlomo

Publikováno v: Biology of Reproduction. 57:217-225

It has been suggested that ovulation may constitute a cyclic inflammatory-like process and that gonadotropin-inducible intraovarian interleukin (IL)-1, an established mediator of inflammation, may play a central role in this regard. In support of thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5b77b703b898758881d17e3099bd29c
https://doi.org/10.1095/biolreprod57.2.217

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The midcycle increase in ovarian glucose uptake is associated with enhanced expression of glucose transporter 3. Possible role for interleukin-1, a putative intermediary in the ovulatory process

Autor: Richard M. Rohan, Eli Y. Adashi, Theresa Davies-Hill, Shahar Kol, Motomu Ando, Ian A. Simpson, Izhar Ben-Shlomo, Kristina Ruutiainen

Publikováno v: Scopus-Elsevier

This study characterizes the rat ovary as a site of hormonally dependent glucose transporter (Glut) expression, and explores the potential role of interleukin (IL)-1, a putative intermediary in the ovulatory process, in this regard. Molecular probing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863ef239d998ea873be5bce1df8e9315
https://doi.org/10.1172/jci119403

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