Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Motomichi Fujita"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6591 (2024)
Senescence is a physiological and pathological cellular program triggered by various types of cellular stress. Senescent cells exhibit multiple characteristic changes. Among them, the characteristic flattened and enlarged morphology exhibited in sene
Externí odkaz:
https://doaj.org/article/a2a1d553de8f42489ed2f6a3bfbc877c
Publikováno v:
Encyclopedia, Vol 1, Iss 2, Pp 350-359 (2021)
Biofunctional peptide FNIII14, which is derived from the 14th fibronectin (FN) type III-like (FN-III) repeat of FN molecule, is capable of inhibiting cell adhesion to the extracellular matrix (ECM). This functional site is usually buried within the m
Externí odkaz:
https://doaj.org/article/6a1704e608e64432b569dd5d308778d0
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Tenascin (TN)-C is highly expressed specifically in the lesions of inflammation-related diseases, including tumors. The expression level of TN-C in tumors and the tumor stroma is positively correlated with poor prognosis. However, no drugs targeting
Externí odkaz:
https://doaj.org/article/41e8301fa7a44bcfb4168a4327b37358
Publikováno v:
Molecules, Vol 25, Iss 14, p 3239 (2020)
Matricellular proteins, which exist in association with the extracellular matrix (ECM) and ECM protein molecules, harbor functional sites within their molecular structures. These functional sites are released through proteolytic cleavage by inflammat
Externí odkaz:
https://doaj.org/article/b8b1ab0d631b4711953509614142d456
Autor:
Motomichi Fujita, Yuka Ito-Fujita, Takuya Iyoda, Manabu Sasada, Yuko Okada, Kazuma Ishibashi, Takuro Osawa, Hiroaki Kodama, Fumio Fukai, Hideo Suzuki
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2752 (2019)
Inflammatory bowel diseases increase the risk of colorectal cancer and colitis-associated colorectal cancer (CAC). Tenascin-C, a matricellular protein, is highly expressed in inflammatory bowel diseases, especially colorectal cancer. However, the rol
Externí odkaz:
https://doaj.org/article/27b6890f6ee54229a8dd63ed5fe47b2f
Autor:
Motomichi Fujita, Tetsuya Yamamoto, Takuya Iyoda, Tatsuya Fujisawa, Reo Nagai, Chikako Kudo, Manabu Sasada, Hiroaki Kodama, Fumio Fukai
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3183 (2019)
Expression level of tenascin-C is closely correlated to poor prognosis in glioblastoma patients, while the substantial role of tenascin-C responsible for aggressive progression in glioblastoma cells has not been clarified. We previously found that pe
Externí odkaz:
https://doaj.org/article/92b9937350cc4065b2fd77f663dccc67
Autor:
Takuya Iyoda, Yumi Nagamine, Yoshitomi Nakane, Yuya Tokita, Shougo Akari, Kazuki Otsuka, Motomichi Fujita, Keisuke Itagaki, You-Ichi Takizawa, Hiroaki Orita, Toshiyuki Owaki, Jyunichi Taira, Ryo Hayashi, Hiroaki Kodama, Fumio Fukai
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162525 (2016)
The acquisition of drug resistance mediated by the interaction of tumor cells with the extracellular matrix (ECM), commonly referred to as cell adhesion-mediated drug resistance (CAM-DR), has been observed not only in hematopoietic tumor cells but al
Externí odkaz:
https://doaj.org/article/7ca555ab31244a85abea6be1068b9b8c
Autor:
Fumio Fukai, Hiroaki Kodama, Sadahiro Kamiya, Kazuki Otsuka, Chikako Kudo, Reo Nagai, Manabu Sasada, Tatsuya Fujisawa, Takuya Iyoda, Tetsuya Yamamoto, Motomichi Fujita
Antibody information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446d92aab6b6f0de9a176bf52748c3b6
https://doi.org/10.1158/1535-7163.22510176
https://doi.org/10.1158/1535-7163.22510176
Autor:
Fumio Fukai, Hiroaki Kodama, Sadahiro Kamiya, Kazuki Otsuka, Chikako Kudo, Reo Nagai, Manabu Sasada, Tatsuya Fujisawa, Takuya Iyoda, Tetsuya Yamamoto, Motomichi Fujita
Tenascin-C is a member of the matricellular protein family, and its expression level is correlated to poor prognosis in cancer, including glioblastoma, whereas its substantial role in tumor formation and malignant progression remains controversial. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c918be3f28d516bd03eec1aca351d9
https://doi.org/10.1158/1535-7163.c.6539535
https://doi.org/10.1158/1535-7163.c.6539535
Autor:
Fumio Fukai, Hiroaki Kodama, Sadahiro Kamiya, Kazuki Otsuka, Chikako Kudo, Reo Nagai, Manabu Sasada, Tatsuya Fujisawa, Takuya Iyoda, Tetsuya Yamamoto, Motomichi Fujita
This file shows the supplementary figure (S1-S8).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003cb4a421dc30e3a072482e77f5482f
https://doi.org/10.1158/1535-7163.22510203.v1
https://doi.org/10.1158/1535-7163.22510203.v1