Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Motomi Enomoto-Iwamoto"'
Autor:
Zuozhen Tian, Frances S. Shofer, Mingyue Fan, Alec Z. Sandroni, Lutian Yao, Lin Han, Ling Qin, Motomi Enomoto-Iwamoto, Yejia Zhang
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 101059- (2024)
Externí odkaz:
https://doaj.org/article/8e54348c408f41e080b362813cc2c8dc
Autor:
Takeshi Oichi, Joe Kodama, Kimberly Wilson, Hongying Tian, Yuka Imamura Kawasawa, Yu Usami, Yasushi Oshima, Taku Saito, Sakae Tanaka, Masahiro Iwamoto, Satoru Otsuru, Motomi Enomoto-Iwamoto
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Longitudinal bone growth relies on endochondral ossification in the cartilaginous growth plate, where chondrocytes accumulate and synthesize the matrix scaffold that is replaced by bone. The chondroprogenitors in the resting zone maintain th
Externí odkaz:
https://doaj.org/article/32712dc2988e468b96d954c8e2a367f3
Publikováno v:
Bone Reports, Vol 17, Iss , Pp 101616- (2022)
Endochondral bone formation is an important pathway in fracture healing, involving the formation of a cartilaginous soft callus and the process of cartilage-to-bone transition. Failure or delay in the cartilage-to-bone transition causes an impaired b
Externí odkaz:
https://doaj.org/article/556166da799440b58d4139aee00c47b4
Autor:
Yejia Zhang, Zuozhen Tian, David Gerard, Lutian Yao, Frances S. Shofer, Gabriella Cs-Szabo, Ling Qin, Maurizio Pacifici, Motomi Enomoto-Iwamoto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract We found ADAM8 enzymatic activity elevated in degenerative human intervertebral disc (IVD). Here, we examined the discs in ADAM8-inactivation mice that carry a mutation preventing self-activation of the enzyme. Surprisingly, elevated gene ex
Externí odkaz:
https://doaj.org/article/29482a7dd36f42fc82304c841792897b
Autor:
Amanda L. Scheiber, Kevin J. Wilkinson, Akiko Suzuki, Motomi Enomoto-Iwamoto, Takashi Kaito, Kathryn S.E. Cheah, Masahiro Iwamoto, Sergey Leikin, Satoru Otsuru
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
Short stature is a major skeletal phenotype in osteogenesis imperfecta (OI), a genetic disorder mainly caused by mutations in genes encoding type I collagen. However, the underlying mechanism is poorly understood, and no effective treatment is availa
Externí odkaz:
https://doaj.org/article/912a9a27ba214f7fad0dbf4f9dd0c58f
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213912 (2019)
Glucose metabolism is altered in injured and healing tendons. However, the mechanism by which the glucose metabolism is involved in the pathogenesis of tendon healing process remains unclear. Injured tendons do not completely heal, and often induce f
Externí odkaz:
https://doaj.org/article/88aa228b4ef849e490a7eff6f2b626f0
Autor:
Maria Elena Candela, Chao Wang, Aruni T Gunawardena, Kairui Zhang, Leslie Cantley, Rika Yasuhara, Yu Usami, Noelle Francois, Masahiro Iwamoto, Arjan van der Flier, Yejia Zhang, Ling Qin, Lin Han, Motomi Enomoto-Iwamoto
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156783 (2016)
Osteoarthritis (OA) is one of most common skeletal disorders and can affect synovial joints such as knee and ankle joints. α5 integrin, a major fibronectin receptor, is expressed in articular cartilage and has been demonstrated to play roles in syno
Externí odkaz:
https://doaj.org/article/cad34fbf26374385921efaad04d945d4
Autor:
Haoruo Jia, Xiaoyuan Ma, Basak Doyran, Wei Tong, Zeyang Sun, Zhaochun Yang, Xianrong Zhang, Abhishek Chandra, James Wang, Lin Han, Motomi Enomoto-Iwamoto, Ling Qin
Publikováno v:
Journal of Orthopaedic Translation, Vol 7, Iss C, p 90 (2016)
Externí odkaz:
https://doaj.org/article/57cad7373f644dbbae73c3ec411af0a4
Autor:
Tao Gui, Yulong Wei, Lijun Luo, Jun Li, Leilei Zhong, Lutian Yao, Frank Beier, Charles L. Nelson, Andrew Tsourkas, X. Sherry Liu, Motomi Enomoto‐Iwamoto, Feifan Yu, Zhiliang Cheng, Ling Qin
Publikováno v:
Journal of Bone and Mineral Research. 37:2498-2511
Posttraumatic osteoarthritis (PTOA) results in joint pain, loss of joint function, and impaired quality of daily life in patients with limited treatment options. We previously demonstrated that epidermal growth factor receptor (EGFR) signaling is ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745a70e8f15f03a5eee60f7a24bf5bb9
https://doi.org/10.1002/jbmr.4717
https://doi.org/10.1002/jbmr.4717
Publikováno v:
The American Journal of Pathology. 191:2042-2051
Osteochondromas are cartilage-capped tumors that arise near growing physes and are the most common benign bone tumor in children. Osteochondromas can lead to skeletal deformity, pain, loss of motion, and neurovascular compression. Currently, surgery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae44c56fc5b39fe60384524b17bdabbc
https://doi.org/10.1016/j.ajpath.2021.08.003
https://doi.org/10.1016/j.ajpath.2021.08.003