Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Motomi, Torii"'
Publikováno v:
mSphere, Vol 8, Iss 4 (2023)
ABSTRACT During invasion, Plasmodium parasites secrete proteins from rhoptry and microneme apical end organelles, which have crucial roles in attaching to and invading target cells. A sporozoite stage-specific gene silencing system revealed that rhop
Externí odkaz:
https://doaj.org/article/a309027566ce4609a22632b568bec990
Autor:
Daisuke Ito, Yoko Kondo, Eizo Takashima, Hideyuki Iriko, Amporn Thongkukiatkul, Motomi Torii, Hitoshi Otsuki
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Plasmodium species cause malaria, and in the instance of Plasmodium falciparum is responsible for a societal burden of over 600,000 deaths annually. The symptoms and pathology of malaria are due to intraerythocytic parasites. Erythrocyte invasion is
Externí odkaz:
https://doaj.org/article/5c8ac82061754dba9442111bf2291dbf
Autor:
Wei-Chiao Huang, Moustafa T. Mabrouk, Luwen Zhou, Minami Baba, Mayumi Tachibana, Motomi Torii, Eizo Takashima, Emily Locke, Jordan Plieskatt, C. Richter King, Camila H. Coelho, Patrick E. Duffy, Carole Long, Takafumi Tsuboi, Kazutoyo Miura, Yimin Wu, Tomoko Ishino, Jonathan F. Lovell
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Co-display of two P. falciparum malaria vaccine antigens (Pfs230D1+ and CSP) on the surface of immunogenic liposomes results in functional immune responses upon immunization of mice and rabbits. Combining both antigens produces immune responses that
Externí odkaz:
https://doaj.org/article/f8e6b970eebc47eab359d0eb8d1b356e
Autor:
Hitoshi Otsuki, Osamu Kaneko, Daisuke Ito, Yoko Kondo, Hideyuki Iriko, Tomoko Ishino, Mayumi Tachibana, Takafumi Tsuboi, Motomi Torii
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 458 (2023)
Plasmodium malaria parasites use erythrocyte-binding-like (EBL) ligands to invade erythrocytes in their vertebrate host. EBLs are released from micronemes, which are secretory organelles located at the merozoite apical end and bind to erythrocyte sur
Externí odkaz:
https://doaj.org/article/4592342b3f984cf09f7710077db0ad83
Autor:
Rachaneeporn Jenwithisuk, Niwat Kangwanrangsan, Mayumi Tachibana, Amporn Thongkukiatkul, Hitoshi Otsuki, Jetsumon Sattabongkot, Takafumi Tsuboi, Motomi Torii, Tomoko Ishino
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-15 (2018)
Abstract Background For the success of the malaria control and eradication programme it is essential to reduce parasite transmission by mosquito vectors. In the midguts of mosquitoes fed with parasite-infected blood, sexual-stage parasites fertilize
Externí odkaz:
https://doaj.org/article/4feec7f98c1240dabf4ea99a9e63a47b
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT In the Plasmodium life cycle, two infectious stages of parasites, merozoites and sporozoites, share rhoptry and microneme apical structures. A crucial step during merozoite invasion of erythrocytes is the discharge to the host cell membrane
Externí odkaz:
https://doaj.org/article/9c483a5c473245cd8803c461b418c152
Autor:
Naohito Tokunaga, Mamoru Nozaki, Mayumi Tachibana, Minami Baba, Kazuhiro Matsuoka, Takafumi Tsuboi, Motomi Torii, Tomoko Ishino
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
In the Plasmodium lifecycle two infectious stages of parasites, merozoites, and sporozoites, efficiently infect mammalian host cells, erythrocytes, and hepatocytes, respectively. The apical structure of merozoites and sporozoites contains rhoptry and
Externí odkaz:
https://doaj.org/article/c59c37166d4246bca08261494f5949df
Autor:
Silvia A. Arredondo, Kristian E. Swearingen, Thomas Martinson, Ryan Steel, Dorender A. Dankwa, Anke Harupa, Nelly Camargo, William Betz, Vladimir Vigdorovich, Brian G. Oliver, Niwat Kangwanrangsan, Tomoko Ishino, Noah Sather, Sebastian Mikolajczak, Ashley M. Vaughan, Motomi Torii, Robert L. Moritz, Stefan H. I. Kappe
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Within the liver, Plasmodium sporozoites traverse cells searching for a “suitable” hepatocyte, invading these cells through a process that results in the formation of a parasitophorous vacuole (PV), within which the parasite undergoes intracellul
Externí odkaz:
https://doaj.org/article/4398165573ac4b7799ec59cf796a37f9
Autor:
Tomoko Ishino, Hikaru Nagaoka, Mayumi Tachibana, Takafumi Tsuboi, Eizo Takashima, Kazutoyo Miura, Masayuki Morita, Bernard N. Kanoi, Minami Baba, Motomi Torii
Publikováno v:
Expert Review of Vaccines. 18:1017-1027
Introduction: Highly effective malaria vaccines are essential component toward malaria elimination. Although the leading malaria vaccine, RTS,S/AS01, with modest efficacy is being evaluated in a pilot feasibility trial, development of a malaria trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9f4e0735b921334a581ce9f2325a5a
https://doi.org/10.1080/14760584.2019.1674145
https://doi.org/10.1080/14760584.2019.1674145
Autor:
Kazuhiro Matsuoka, Motomi Torii, Amporn Thongkukiatkul, Takafumi Tsuboi, Mayumi Tachibana, Minami Baba, Tomoko Ishino, Natcha Lorsuwannarat, Sirasate Bantuchai, Mamoru Nozaki
Publikováno v:
International Journal for Parasitology. 49:725-735
The malaria parasite sporozoite sequentially invades mosquito salivary glands and mammalian hepatocytes; and is the Plasmodium lifecycle infective form mediating parasite transmission by the mosquito vector. The identification of several sporozoite-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fe802830963995abccefbe1460caa7
https://doi.org/10.1016/j.ijpara.2019.05.001
https://doi.org/10.1016/j.ijpara.2019.05.001