Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Motokazu Tsuneto"'
Autor:
Takayuki Wakimizu, Junpei Naito, Manabu Ishida, Yasutaka Kurata, Motokazu Tsuneto, Yasuaki Shirayoshi, Ichiro Hisatome
Publikováno v:
Journal of Arrhythmia, Vol 39, Iss 4, Pp 664-668 (2023)
Abstract Background Cardiomyocytes derived from human iPS cells (hiPSCs) include cells showing SAN‐ and non‐SAN‐type spontaneous APs. Objectives To examine whether the deep learning technology could identify hiPSC‐derived SAN‐like cells sho
Externí odkaz:
https://doaj.org/article/dbf7b7edc7db441ea0cd27e9a6940e7e
Autor:
Takayuki Wakimizu, Kumi Morikawa, Kenta Fukumura, Tetsuo Yuki, Takashi Adachi, Yasutaka Kurata, Junichiro Miake, Ichiro Hisatome, Motokazu Tsuneto, Yasuaki Shirayoshi
Publikováno v:
Regenerative Therapy, Vol 21, Iss , Pp 239-249 (2022)
Introduction: Dysfunction of the sinoatrial node (SAN) cells causes arrhythmias, and many patients require artificial cardiac pacemaker implantation. However, the mechanism of impaired SAN automaticity remains unknown, and the generation of human SAN
Externí odkaz:
https://doaj.org/article/3fa7457577374453870a7ddfa7f4b60b
Autor:
Sayaka Yonemizu, Keiichiro Masuda, Yasutaka Kurata, Tomomi Notsu, Yuhei Higashi, Kenta Fukumura, Peili Li, Haruaki Ninomiya, Junichiro Miake, Motokazu Tsuneto, Yasuaki Shirayoshi, Ichiro Hisatome
Publikováno v:
Regenerative Therapy, Vol 10, Iss , Pp 104-111 (2019)
Introduction: Human induced pluripotent stem cells (hiPSCs) harboring cardiac myosin heavy chain 6 promoter can differentiate into functional cardiomyocytes called “iCell cardiomyocytes” under blasticidin treatment condition. While iCell cardiomy
Externí odkaz:
https://doaj.org/article/def4b98bfa7240ef80fa4eb7f9b92092
Autor:
Kenshiro Yamamoto, Yasutaka Kurata, Yumiko Inoue, Maya Adachi, Motokazu Tsuneto, Junichiro Miake, Kazuhide Ogino, Haruaki Ninomiya, Akio Yoshida, Yasuaki Shirayoshi, Yoshiko Suyama, Shunjiro Yagi, Motonobu Nishimura, Kazuhiro Yamamoto, Ichiro Hisatome
Publikováno v:
Regenerative Therapy, Vol 9, Iss , Pp 79-88 (2018)
Introduction: Cell sheets using myoblasts have been developed for the treatment of heart failure after myocardial infarction (MI) bridging to heart transplantation. Stem cells are supposed to be better than myoblasts as a source of cells, since they
Externí odkaz:
https://doaj.org/article/8424ccd4baac4e36a45ac17919b4a92d
Autor:
Julia Tornack, Katharina Seiler, Andreas Grützkau, Joachim R Grün, Masafumi Onodera, Fritz Melchers, Motokazu Tsuneto
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70116 (2013)
The transcription factors SCL/Tal-1 and AML1/Runx1 control the generation of pluripotent hematopoietic stem cells (pHSC) and, thereby, primitive and definitive hematopoiesis, during embryonic development of the mouse from mesoderm. Thus, Runx1-defici
Externí odkaz:
https://doaj.org/article/d0736c5aeedd4fa68447cfd95c743a13
Autor:
Maki Morita, Yoshiko Suyama, Tomomi Notsu, Kohei Fukuoka, Kento Ikuta, Haruka Kanayama, Ryunosuke Umeda, Shogo Teraoka, Hiroyuki Minato, Haruaki Ninomiya, Motokazu Tsuneto, Yasuaki Shirayoshi, Ichiro Hisatome, Shunjiro Yagi
Publikováno v:
Annals of Plastic Surgery. 90:171-179
Autor:
Peili Li, Yasutaka Kurata, Fikri Taufiq, Masanari Kuwabara, Haruaki Ninomiya, Katsumi Higaki, Motokazu Tsuneto, Yasuaki Shirayoshi, Miguel A. Lanaspa, Ichiro Hisatome
Publikováno v:
Molecular Biology Reports. 49:5939-5952
Background Gout is usually found in patients with atrial fibrillation (AF). K+ efflux is a common trigger of NLRP3 inflammasome activation which is involved in the pathogenesis of AF. We investigated the role of the K+ channel Kv1.5 in monosodium ura
Autor:
Shin Ito, Tomomi Notsu, Junichiro Miake, Yasuaki Shirayoshi, Masanari Kuwabara, Haruaki Ninomiya, Takayuki Wakimizu, Kumi Morikawa, Kazuhiro Yamamoto, Kenshiro Yamamoto, Mai Watanabe, Motonobu Nishimura, Takuki Sakaguchi, Maya Adachi, Takayuki Morisaki, Motokazu Tsuneto, Masafumi Kitakaze, Yasutaka Kurata, Yumiko Inoue, Hiromu Horie, Ichiro Hisatome
Publikováno v:
Circulation Journal. 85:657-666
Background Although adipose-derived stem cell (ADSC) sheets improve the cardiac function after myocardial infarction (MI), underlying mechanisms remain to be elucidated. The aim of this study was to determine the fate of transplanted ADSC sheets and
Autor:
Motoshi Ouchi, Akio Yoshida, Hiromi Sakaguchi, Naohiko Anzai, Nani Maharani, Yasutaka Kurata, Kazuhiro Yamamoto, Junichiro Miake, Katsumi Higaki, Nobuhito Ikeda, Naoe Nakasone, Motokazu Tsuneto, Masanari Kuwabara, Haruaki Ninomiya, Yasuaki Shirayoshi, Peili Li, Ichiro Hisatome, Naoyuki Otani, Tomomi Notsu
Publikováno v:
Circulation Reports
Background: Monocarboxylate transporter 9 (MCT9), an orphan transporter member of the solute carrier family 16 (SLC16), possibly reabsorbs uric acid in the renal tubule and has been suggested by genome-wide association studies to be involved in the d
Autor:
Yasuaki Shirayoshi, Satoshi Miyazaki, Yasutaka Kurata, Kazuhiro Yamamoto, Akira Ohtahara, Tetsuya Yamamoto, Masanari Kuwabara, Haruaki Ninomiya, Toshihiro Hamada, Kimiyoshi Ichida, Junichiro Miake, Einosuke Mizuta, Fikri Taufiq, Kazuhide Ogino, Ichiro Hisatome, Motokazu Tsuneto, Aiko Takami, Peili Li, Shinobu Sugihara, Masahiko Kato
Publikováno v:
Vascular Failure. 3:59-67