Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Motohiro, Hamaguchi"'
Autor:
Shiro Ibe, Motohiro Hamaguchi, Teiichiro Shiino, Seiichiro Fujisaki, Naoto Mamiya, Junko Hattori, Rie Tanaka, Makoto Utsumi, Yasumasa Iwatani, Shingo Kato, Yoshiyuki Yokomaku, Wataru Sugiura
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 54:241-247
Background Five HIV-2-seropositive cases were recently identified in Japan, outside the HIV-2 endemic area of West Africa. To clarify the molecular epidemiology of HIV-2 in Japan, we analyzed sequences of these cases in detail. Methods HIV-2 genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33e7f9c58755a10df3f9263c87bd3b1
https://doi.org/10.1097/qai.0b013e3181dc98c1
https://doi.org/10.1097/qai.0b013e3181dc98c1
Autor:
Motohiro Hamaguchi, Hiromi Okada, Hidehiko Saito, Shinji Kunishima, Koji Yamamoto, Tetsuhito Kojima, Junki Takamatsu, Tadashi Matsushita, Tomio Yamazaki, Akira Takagi
Publikováno v:
Thrombosis Research. 125:e246-e250
Protein S (PS) is a member of the vitamin K-dependent protein family containing similar γ-carboxyglutamic acid (Gla) domains, although only PS has a thrombin-sensitive region (TSR), which is located between the Gla domain and the first epidermal gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9cd2a4cf1c2498ba26226fa6e63390
https://doi.org/10.1016/j.thromres.2009.11.029
https://doi.org/10.1016/j.thromres.2009.11.029
Autor:
Tsuneo Sasaki, Motohiro Hamaguchi, Kenichi Ishizawa, Michinori Ogura, Hisayuki Yokoyama, Hisashi Sakamaki, Kazunori Ohnishi, Tomomitsu Hotta, Yasuo Morishima, Hideo Harigae
Publikováno v:
Cancer Science. 100:357-362
The purpose of this study was to investigate the safety profile of SR29142 when administered as a single agent both prior to chemotherapy and during treatment, and to compare the efficacy of SR29142 administered at two dose levels in adult Japanese p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a772d8c09febb6985aa08ab28f1d40b
https://doi.org/10.1111/j.1349-7006.2008.01047.x
https://doi.org/10.1111/j.1349-7006.2008.01047.x
Autor:
Naoto Mamiya, Junko Hattori, Motohiro Hamaguchi, Urara Shigemi, Kazuyo Nakamura, Kayoko Shimizu, Saeko Fujisaki, Seiichiro Fujisaki, Shiro Ibe, Yoshiyuki Yokomaku, Tsuguhiro Kaneda, Makoto Utsumi
Publikováno v:
AIDS Research and Human Retroviruses. 25:15-21
To monitor active HIV-1 transmission in Nagoya, Japan, we have been determining the subtypes of HIV-1 infecting therapy-naive individuals who have newly visited the Nagoya Medical Center since 1997. The subtypes were determined by phylogenetic analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94525e4058b9ad0527e6d1b29d719b3c
https://doi.org/10.1089/aid.2008.0056
https://doi.org/10.1089/aid.2008.0056
Autor:
Naoto Mamiya, Seiichiro Fujisaki, Shiro Ibe, Junko Hattori, Kaori Sawaki, Motohiro Hamaguchi, Urara Shigemi, Tsuguhiro Kaneda, Yoshiyuki Yokomaku
Publikováno v:
AIDS Research and Human Retroviruses. 24:1121-1125
We analyzed a total of 12 near full-length genomes of drug-resistant HIV-1 spreading among therapy-naive individuals in Nagoya, Japan. Genomes comprised seven protease inhibitor (PI)-resistant viruses possessing an M46I (n = 6) or L90M mutation (n =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d745f7cbdc11b42a2a756210981737
https://doi.org/10.1089/aid.2008.0090
https://doi.org/10.1089/aid.2008.0090
Autor:
Isamu Sugiura, Yoshihisa Morishita, Tomoki Naoe, Koichi Miyamura, Akio Kohno, Toshiki Uchida, Hiroshi Sao, Masashi Sawa, Motohiro Hamaguchi, Hiroatsu Iida, Kazuhito Yamamoto, Shuichi Mizuta, Masamitsu Yanada
Publikováno v:
International Journal of Hematology. 87:210-216
Acute promyelocytic leukemia (APL) is the most curable subtype of acute myeloid leukemia. Second complete remission (CR2) can be easily achieved with several therapeutic options even after relapse. However, the optimal strategy to treat APL in CR2 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb071c52efc64a33e887d6466ee9268
https://doi.org/10.1007/s12185-008-0020-8
https://doi.org/10.1007/s12185-008-0020-8
Publikováno v:
European Journal of Haematology. 80:540-544
MYH9 disorders are autosomal dominant macrothrombocytopenias with leukocyte inclusion bodies. Single point mutations in the protein-coding sequence of the MYH9 gene are the most common cause. So far no large gene deletion/insertion and splicing defec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8ee67a63e561522beea488dc81110ac
https://doi.org/10.1111/j.1600-0609.2008.01046.x
https://doi.org/10.1111/j.1600-0609.2008.01046.x
Autor:
Naoto Mamiya, Saeko Fujisaki, Yoshiyuki Yokomaku, Kazuyo Nakamura, Junko Hattori, Shiro Ibe, Motohiro Hamaguchi, Urara Shigemi, Tsuguhiro Kaneda, Takejiro Kazumi, Kayoko Shimizu, Seiichiro Fujisaki
Publikováno v:
AIDS Research and Human Retroviruses. 24:7-14
We studied the emergence of drug-resistant human immunodeficiency virus type 1 (HIV-1) with major amino acid mutations in 402 therapy-naive patients at Nagoya Medical Center, Japan, between 1999 and 2006. The mean prevalence of drug-resistant HIV-1 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a0cd5d5b2ff5ca210e9c32b4865e69
https://doi.org/10.1089/aid.2007.0129
https://doi.org/10.1089/aid.2007.0129
Autor:
Takuma Shirasaka, Shuzo Matsushita, Tsunefusa Hayashida, Hiroyuki Gatanaga, Masahiro Yamamoto, Takeshi Kuwahara, Munehiro Yoshino, Takao Koike, Kiyoto Tsuchiya, Noboru Takata, Masahide Horiba, Isao Sato, Hiroki Tsukada, Katsuya Fujimoto, Akiro Kimura, Mikio Ueda, Fumitake Gejyo, Motohiro Hamaguchi, Shinichi Oka, Satoshi Kimura
Publikováno v:
Clinical Infectious Diseases. 45:1230-1237
Background Efavirenz (EFV) is metabolized primarily by cytochrome P450 2B6 (CYP2B6), and high plasma concentrations of the drug are associated with a G-->T polymorphism at position 516 (516G-->T) of CYP2B6 and frequent central nervous system (CNS)-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363567e58972b821275451a36cdd31e0
https://doi.org/10.1086/522175
https://doi.org/10.1086/522175
Autor:
Masaaki Takahashi, Naoto Mamiya, Shiro Ibe, Naoya Okumura, Tsuguhiro Kaneda, Motohiro Hamaguchi, Tatsuo Suzuki, Yuichi Kudaka, Atsushi Hirano
Publikováno v:
AIDS Research and Human Retroviruses. 23:983-987
The present study assessed the relationship between central nervous system (CNS) side effects and plasma concentrations of efavirenz (EFV) in Japanese HIV-1-infected patients. Subjects consisted of 69 HIV-1-infected patients (57 therapy-naive and 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb528059c48c392f17ac1768ce12b9e9
https://doi.org/10.1089/aid.2006.0193
https://doi.org/10.1089/aid.2006.0193