Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Motohiko Shimizu"'
Autor:
Toshihiko Toki, Ikuo Konishi, Shingo Fujii, Motohiko Shimizu, Tanri Shiozawa, Toshio Nikaido, Kiyoshi Kato
Publikováno v:
International Journal of Gynecological Pathology. 22:334-340
Minichromosome maintenance (MCM) proteins are essential for cell cycling due to their function as replication-licensing factors. The aim of the present study was to investigate the clinicopathologic implications of the MCM2 and MCM3 in endometrial ca
Autor:
Ikuko Nakai, Isao Shiozawa, Kazuko Itoh, Akiko Horiuchi, Teruyuki Yamazaki, Kaoru Kimura, Noritane Ueda, Motohiko Shimizu, Ikuo Konishi, Akihiko Suzuki
Publikováno v:
Gynecologic Oncology. 88:309-317
Objective The natural history of the development of ovarian carcinoma is not known. It also remains undetermined whether ovarian carcinomas develop from benign and/or borderline malignant tumors or arise de novo from the ovarian surface epithelium. M
Autor:
Kiyoshi Kato, Mieko Horikawa, Keiko Ishii, Toshihiko Toki, Motohiko Shimizu, Ikuo Konishi, Shigeko Hayashi
Publikováno v:
The Journal of the Japanese Society of Clinical Cytology. 40:646-649
Publikováno v:
International Journal of Gynecological Pathology. 19:158-163
The Wilms' tumor gene WT1 plays multiple roles in the development of the genitourinary organs and Wilms' tumors. The aims of this study were to immunohistochemically evaluate WT1 expression in normal female genital tissues and in epithelial ovarian t
Autor:
Tanri Shiozawa, Toshio Nikaido, Keiko Ishii, Shingo Fujii, Toshihiko Toki, Shigeki Shiohara, Motohiko Shimizu
Publikováno v:
Cancer. 80:908-916
BACKGROUND Mucinous tumors of the ovary have been thought to originate in two ways: by mullerian-type metaplasia of surface epithelium, and as monodermal teratomas. To gain a better understanding of their pathogenesis, the authors analyzed these tumo
Autor:
Akiko, Horiuchi, Tsutomu, Imai, Motohiko, Shimizu, Kenji, Oka, Cuiju, Wang, Toshio, Nikaido, Ikuo, Konishi
Publikováno v:
Anticancer research. 22(5)
Hypoxia is important in cancer progression, and at the stage of detachment of the cancer cells from the primary lesion. This study was undertaken to analyze the effect of hypoxia on angiogenesis and cell proliferation in ovarian cancer.We first used
Publikováno v:
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 21(1)
Using the immunohistochemical technique, we investigated the expression of CD10 in normal female genital tissues, chorionic villi and decidua of early gestation, endometriotic lesions, and uterine mesenchymal tumors. The cytoplasm of normal endometri
Publikováno v:
Cancer. 85(3)
BACKGROUND The purpose of this study was to identify biologic differences between ovarian clear cell carcinoma and other ovarian adenocarcinomas by comparing the expression of cell cycle regulatory molecules and by analyzing the survival of the patie
Publikováno v:
Molecular human reproduction. 4(12)
The aim of the present study was to gain a better understanding of the localization of apoptotic cells within the human endometrium during the menstrual cycle and to elucidate the relationships among the following for the human endometrium: apoptosis
Publikováno v:
Cancer. 80(12)
BACKGROUND Abnormalities in G1 cell cycle regulation have been associated with the malignant transformation of cells. To obtain further information about the role of factors regulating the G1 cell cycle in the development of endometrial carcinoma, th