Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Motoharu Ju-ichi"'
Autor:
Eri Torii, Yusuke Kobayashi, Kaori Takahashi, Motoharu Ju-ichi, Hiroyo Nagata, Tetsutaro Kimachi
Publikováno v:
Synlett. 2011:365-368
A series of unsymmetrical 2,3-diaryl epoxides were hydrogenatedunder transfer-hydrogenation conditions using the polyurea-encapsulatedpalladium catalyst [Pd(0)EnCat TM ].The position of the cleaved C-O bond was determined by ¹ HNMR analysis of the r
Publikováno v:
Chemical and Pharmaceutical Bulletin. 59:753-756
Synthesis of dehydoriso-β-lapachone (1) in both racemic and enantioenriched forms is achieved starting from reduced naphthoquinone equivalents. As for the synthesis of enantioenriched dehydroiso-β-lapachone, introduction of the asymmetric center wa
Publikováno v:
Synlett. 2010:2330-2334
Asymmetric Darzens-type epoxide formation of aryl aldehydes with chiral para-substituted benzylammonium ylides, prepared from brucine and corresponding benzylic chlorides and treated in situ under basic condition, was carried out to afford chiral 2,3
Publikováno v:
Tetrahedron: Asymmetry. 20:1683-1689
Starting from a reduced lapachol compound, the total synthesis of rhinacanthin A in both racemic and enantioenriched forms is achieved in eight steps without forming any undesired β-lapachone derivatives. For the synthesis of enantioenriched rhinaca
Autor:
Chihiro Ito, Yoshimi Kitaguchi, Yu Jinguji, Masumi Kurosawa, Kaori Ushijima, Asae Ochi, Naoko Negi, Motoharu Ju-ichi, Naoko Teshima, Yukako Kitaji, Keiko Saito, Ahmad Muhamad Abou-Dough, Eri Kusakabe
Publikováno v:
Natural product communications. 10(4)
Four new coumarins, isomurralonginol senecioate (1), isomurralonginoic acid (2), murrangatin 2′-formate (3), and meranzin hydrate 2′-palmitate (4), were isolated from the vegetative branches of Murraya exotica together with 33 known compounds. Th
Publikováno v:
Natural product communications. 10(2)
Four new coumarins, murrangatin-1′-senecioate (1), 5-methoxypanial (2), mexoticin-2′-senecioate (3) and murralongic acid (4), were isolated from the leaves of Murraya paniculata var. zollingeri, together with 23 known coumarins. The structures of
Autor:
Motoharu Ju-ichi
Publikováno v:
YAKUGAKU ZASSHI. 125:231-254
The constituents of Citrus plants were investigated to develop useful agents that are effective in cancer chemoprevention. We examined the roots and bark of the roots of various Citrus plants, resulting in the isolation of many novel compounds. Their
Publikováno v:
Tetrahedron. 61:2607-2622
We designed two aromatic analogues 1a and 1b of macrolactin A with expectation of enhancing biological activity and metabolical stability. As a result of retrosynthetic analysis of these compounds 1a–b , two synthetic strategies have been examined.
Autor:
Hiroshi Furukawa, Motoharu Ju-ichi, Harukuni Tokuda, Naoyuki Sakamoto, Hoyoku Nishino, Masataka Itoigawa, Chihiro Ito
Publikováno v:
Planta Medica. 71:84-87
In order to identify antitumor-promoting agents, we performed primary in vitro screening of 31 coumarins isolated from 11 plants of the Citrus species (Rutaceae), examining their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA
Publikováno v:
Tetrahedron Letters. 45:677-680
Total asymmetric synthesis of macrolactin A analogue was accomplished by the convergent strategy. Rapid access to advanced intermediate 16 through isomerization of ynone to (E,E)-conjugated dienone is a key step of this synthesis. Overall, control of