Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Motoharu Hirano"'
Autor:
Keisuke Tsuchiya, Kanako Horikoshi, Minami Fujita, Motoharu Hirano, Maho Miyamoto, Hidetomo Yokoo, Yosuke Demizu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11768 (2023)
Cell-penetrating peptides (CPPs) are widely used for the intracellular delivery of a variety of cargo molecules, including small molecules, peptides, nucleic acids, and proteins. Many cationic and amphiphilic CPPs have been developed; however, there
Externí odkaz:
https://doaj.org/article/93b752e4577046818092b656962bd457
Autor:
Motoharu Hirano, Chihiro Saito, Hidetomo Yokoo, Chihiro Goto, Ryuji Kawano, Takashi Misawa, Yosuke Demizu
Publikováno v:
Molecules, Vol 26, Iss 2, p 444 (2021)
Magainin 2 (Mag2), which was isolated from the skin of the African clawed frog, is a representative antimicrobial peptide (AMP) that exerts antimicrobial activity via microbial membrane disruption. It has been reported that the helicity and amphipath
Externí odkaz:
https://doaj.org/article/54313c8ebd78468ba8a0071048beccf9
Autor:
Chihiro Hirai, Shigeomi Koike, Motoharu Hirano, Junichi Nishimura, Shiho Akashita, Takahumi Ohkoshi, Yasushi Katsumata
Publikováno v:
Acta Radiologica Open, Vol 1, Iss 11, Pp 1-3 (2012)
Polyarteritis nodosa (PAN) is characterized by multisystem necrotizing vasculitis, primarily affecting small-to-medium-sized muscular arteries, and it is typically found in middle-aged men. PAN is rarely found in the female genital tract (including t
Externí odkaz:
https://doaj.org/article/18493212ede241af8db9e9c55c10e41a
Autor:
Ryuji Kawano, Takashi Misawa, Yosuke Demizu, Chihiro Saito, Chihiro Goto, Motoharu Hirano, Hidetomo Yokoo
Publikováno v:
ChemPlusChem. 85:2731-2736
Antimicrobial peptides (AMPs) are expected to be good candidate molecules for novel antimicrobial therapies. Most AMPs exert their antimicrobial activity through disruption of microbial membranes due to their amphipathic properties. Recently, the hel
Autor:
Yoshihiro Kusayama, Joji Matsubara, Motoharu Hirano, Yutaka Inaba, Akihiro Nakazawa, Ayahiro Kadowaki, Manabu Ide, Tsuyoshi Takeuchi, Ken Kumagai, Kenzo Kanai, Yoori Kim, Hiroshi Fujimaki
Publikováno v:
Modern Rheumatology. 31:987-991
This study aimed to investigate the prevalence of patients with rheumatoid arthritis (RA) at a high risk of major osteoporosis (OP)-related fractures and the status of OP-related medical treatment for these patients.We enrolled 120 patients aged ≥4
Autor:
Chihiro Goto, Ryuji Kawano, Motoharu Hirano, Chihiro Saito, Yosuke Demizu, Hidetomo Yokoo, Takashi Misawa
Publikováno v:
Molecules
Molecules, Vol 26, Iss 444, p 444 (2021)
Volume 26
Issue 2
Molecules, Vol 26, Iss 444, p 444 (2021)
Volume 26
Issue 2
Magainin 2 (Mag2), which was isolated from the skin of the African clawed frog, is a representative antimicrobial peptide (AMP) that exerts antimicrobial activity via microbial membrane disruption. It has been reported that the helicity and amphipath
Publikováno v:
ChemMedChem. 16(8)
Antimicrobial peptides (AMPs) are potential novel therapeutic drugs against microbial infections. Most AMPs function by disrupting microbial membranes because of their amphipathic properties and ordered secondary structures. In this minireview, we de
Autor:
Yoshinobu Aisa, Motoharu Hirano, Chisako Ito, Tomonori Nakazato, Yuki Osada, Satoshi Takanashi, Yuichiro Amano, Hideki Arakaki
Publikováno v:
Rheumatology International. 37:1629-1633
Several reports have shown that patients with rheumatoid arthritis (RA) are at increased risk of developing lymphoproliferative disorders (LPD). Methotrexate (MTX) has been recognized as a major cause of LPD. Sometimes spontaneous regression (SR) occ
Autor:
Chisako Ito, Satoshi Takanashi, Yuki Osada, Takehiko Mori, Yuriko Fujita, Yoshinobu Aisa, Motoharu Hirano, Tomonori Nakazato
Publikováno v:
Annals of Hematology. 97:1489-1491
Autor:
Yukiko Hara-Kudo, Takashi Misawa, Motoharu Hirano, Yutaka Kikuchi, Yosuke Demizu, Chihiro Goto, Katsuhiko Hayashi
Publikováno v:
ChemMedChem. 14(22)
Magainin 2 (Mag 2), which is isolated from the skin of frogs, is a representative antimicrobial peptide (AMP), exerts its antimicrobial activity via microbial membrane disruption. It has been reported that both the amphipathicity and helical structur