Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Motoharu Hayashi"'
Autor:
Kazutoshi Yamaguchi, Motoharu Hayashi, Yasuhiro Uchida, Xian Wu Cheng, Takayuki Nakayama, Tadashi Matsushita, Toyoaki Murohara, Kyosuke Takeshita
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Notch signaling has been recognized recently as a key regulator of metabolism. Here, we determined the role of Notch1 in adipogenesis in wild-type (WT) and Notch1 hetero-mutant (N1+/−) mice provided with 12-week normal or high-fat diet. Ha
Externí odkaz:
https://doaj.org/article/1f7ab7957a43406f90deeb9940a1187c
Autor:
Maimaiti Yisireyili, Motoharu Hayashi, Hongxian Wu, Yasuhiro Uchida, Koji Yamamoto, Ryosuke Kikuchi, Mohammad Shoaib Hamrah, Takayuki Nakayama, Xian Wu Cheng, Tadashi Matsushita, Shigeo Nakamura, Toshimitsu Niwa, Toyoaki Murohara, Kyosuke Takeshita
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Chronic stress is closely linked to the metabolic syndrome, diabetes, hyperuricemia and thromboembolism, but the mechanisms remain elusive. We reported recently that stress targets visceral adipose tissue (VAT), inducing lipolysis, low-grade
Externí odkaz:
https://doaj.org/article/738983d9e26b47f2b5f2eba04fb3afb7
Autor:
Hatsumi Inaba, Kyosuke Takeshita, Yasuhiro Uchida, Motoharu Hayashi, Takahiro Okumura, Akihiro Hirashiki, Daiji Yoshikawa, Hideki Ishii, Koji Yamamoto, Takayuki Nakayama, Masaaki Hirayama, Hiroyuki Matsumoto, Tadashi Matsushita, Toyoaki Murohara
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e83977 (2014)
In repetitive measurements of flow-mediated dilatation (FMD), the duration of the interval between measurements remains controversial. In this pilot study, we conducted three sequential measurements of low-flow-mediated constriction (L-FMC), FMD and
Externí odkaz:
https://doaj.org/article/f1bb87042cdd46f899de034d9ef4a4d7
Autor:
Motoharu Hayashi, Kyosuke Takeshita, Yasuhiro Uchida, Koji Yamamoto, Ryosuke Kikuchi, Takayuki Nakayama, Emiko Nomura, Xian Wu Cheng, Tadashi Matsushita, Shigeo Nakamura, Toyoaki Murohara
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116163 (2014)
A strong causal link exists between psychological stress and insulin resistance as well with hypertension. Meanwhile, stress-related responses play critical roles in glucose metabolism in hypertensive patients. As clinical trials suggest that angiote
Externí odkaz:
https://doaj.org/article/1117d82cb4e54a17b237549cf462bc6f
Autor:
Takashi Okajima, Hiroki Kojima, Akihito Tanaka, Ruka Yoshida, Takayuki Mitsuda, Kenshi Hirayama, Yusuke Hitora, Kenji Furusawa, Hiroshi Tashiro, Naoki Iwakawa, Takeshi Adachi, Kenji Arai, Hideki Ishii, Toyoaki Murohara, Yasuhiro Ogawa, Nariko Motomura, Motoharu Hayashi, Hajime Imai, Katsuhiro Kawaguchi
Publikováno v:
Heart and Vessels. 35:1044-1050
Reduced exercise capacity is known to be an important predictor of poor prognosis and disability in patients with cardiovascular diseases and chronic heart failure, and even members of the general population. However, data about exercise capacity ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf27b79591cd4519601df409a2004077
https://doi.org/10.1007/s00380-020-01576-2
https://doi.org/10.1007/s00380-020-01576-2
Autor:
Kyosuke Takeshita, Xian Wu Cheng, Yasuhiro Uchida, Kazutoshi Yamaguchi, Toyoaki Murohara, Motoharu Hayashi, Takayuki Nakayama, Tadashi Matsushita
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Notch signaling has been recognized recently as a key regulator of metabolism. Here, we determined the role of Notch1 in adipogenesis in wild-type (WT) and Notch1 hetero-mutant (N1+/-) mice provided with 12-week normal or high-fat diet. Haploinsuffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157e4efb56fa0662fbc9fc43f2d72962
https://doi.org/10.1038/s41598-021-96017-z
https://doi.org/10.1038/s41598-021-96017-z
Autor:
Yasuhiro Uchida, Maimaiti Yisireyili, Xian Wu Cheng, Hongxian Wu, Kyosuke Takeshita, Chang-Ning Hao, Koji Yamamoto, Toyoaki Murohara, Tadashi Matsushita, Shigeo Nakamura, Ryosuke Kikuchi, Motoharu Hayashi, Takayuki Nakayama
Publikováno v:
Psychoneuroendocrinology. 73:186-195
Background Stress evokes lipolytic release of free fatty acid (FFA) and low-grade inflammation in visceral adipose tissue, mediated by increased adipokine secretion, and contributes to glucose metabolism disorder and prothrombotic state. We tested th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa64c81740702834646f05132fa7f9a
https://doi.org/10.1016/j.psyneuen.2016.08.004
https://doi.org/10.1016/j.psyneuen.2016.08.004
Autor:
Toshimitsu Niwa, Takayuki Nakayama, Shigeo Nakamura, Hongxian Wu, Tadashi Matsushita, Motoharu Hayashi, Mohammad Shoaib Hamrah, Maimaiti Yisireyili, Kyosuke Takeshita, Ryosuke Kikuchi, Toyoaki Murohara, Koji Yamamoto, Xian Wu Cheng, Yasuhiro Uchida
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports
Scientific Reports
Chronic stress is closely linked to the metabolic syndrome, diabetes, hyperuricemia and thromboembolism, but the mechanisms remain elusive. We reported recently that stress targets visceral adipose tissue (VAT), inducing lipolysis, low-grade inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15c491e32e4d96f46aa704097879058
https://doi.org/10.1038/s41598-017-01366-3
https://doi.org/10.1038/s41598-017-01366-3
Autor:
Yasuhiro Ogawa, Naoaki Kano, Yosuke Murase, Hajime Imai, Katsuhiro Kawaguchi, Motoharu Hayashi
Publikováno v:
Cardiovascular Intervention and Therapeutics. 34:295-296
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a26992d7b62936231acf4fce3cc8a6c
https://doi.org/10.1007/s12928-018-0551-8
https://doi.org/10.1007/s12928-018-0551-8
Autor:
Kyosuke Takeshita, Yasuhiro Uchida, Toyoaki Murohara, Tadashi Matsushita, Koji Yamamoto, Motoharu Hayashi
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 27(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de7eb1eb8afd00bbd2a55c456a7044b
https://pubmed.ncbi.nlm.nih.gov/27023882
https://pubmed.ncbi.nlm.nih.gov/27023882