Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Motoaki, Shichiri"'
Autor:
Yukio Shigeta, Yoshitomo Oka, Kempei Matsuoka, Nigishi Hotta, Takayoshi Toyota, Ryuzo Kawamori, Motoaki Shichiri, Yasuo Akanuma, Nobuo Sakamoto
Publikováno v:
Diabetes Research and Clinical Practice. 77:S263-S268
In order to study a long-term effect along with adverse action of epalrestat, an aldose reductase inhibitor, a randomized, prospective study was conducted over the period of 3 years at 112 facilities. Six hundred and three diabetic patients with medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcbf30d316b03be16827e9e479190e5f
https://doi.org/10.1016/j.diabres.2007.01.069
https://doi.org/10.1016/j.diabres.2007.01.069
Autor:
Yoshitomo Oka, Isao Yoshimura, Motoaki Shichiri, Mitsuyoshi Nakashima, Ryuzo Kawamori, Takayoshi Toyota, Kempei Matsuoka, Nigishi Hotta, Yasuo Akanuma, Nobuo Sakamoto, Yukio Shigeta
Publikováno v:
Diabetes Care. 29:1538-1544
OBJECTIVE—We sought to evaluate the long-term efficacy and safety of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy. RESEARCH DESIGN AND METHODS—Subjects with diabetic neuropathy, median motor nerve conduction veloci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3ca36bad2f95410d568d7bc6de6dab
https://doi.org/10.2337/dc05-2370
https://doi.org/10.2337/dc05-2370
Autor:
Kazuhiko Nakamaru, Kazuya Matsumoto, Eiichi Araki, Noboru Furukawa, Motoaki Shichiri, Tetsuya Shirotani
Publikováno v:
Endocrine Journal. 49:121-130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0916af7fcd1bcfc93b11f1ad4751f3e9
https://doi.org/10.1507/endocrj.49.121
https://doi.org/10.1507/endocrj.49.121
Autor:
Tetsushi Toyonaga, Yousuke Ebina, Hiroyuki Motoshima, Tetsuya Taguchi, Noboru Furukawa, Kazuaki Yoshizato, Eiichi Araki, Yoshiaki Hirashima, Motoaki Shichiri, Junji Kawashima, Tetsuya Shirotani
Publikováno v:
Biochemical and Biophysical Research Communications. 280:428-434
The liver is a major target organ of insulin and is important for glucose homeostasis. We analyzed the tissue specific regulation of the insulin receptor gene in the liver by studying the cis-acting element and trans-acting factor of the human insuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce32bb6ad303f0e72f72a13aa2f8e93
https://doi.org/10.1006/bbrc.2000.4140
https://doi.org/10.1006/bbrc.2000.4140
Autor:
Takayuki Sasahara, Masakazu Sakai, Yoshichika Anami, Motoaki Shichiri, Toru Takemura, Takeshi Matsumura, Hirofumi Matsuda, Takeshi Biwa, Takeshi Nishikawa
Publikováno v:
Atherosclerosis. 152:347-357
Macrophage-derived foam cells are known to play an essential role in the development and progression of atherosclerotic lesions. Probucol prevents oxidative modification of low-density lipoprotein (LDL) and lowers plasma contents of LDL and high-dens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc16430744ea00214b3e17574a4e011f
https://doi.org/10.1016/s0021-9150(99)00500-6
https://doi.org/10.1016/s0021-9150(99)00500-6
Autor:
Shoaib Chowdhury, Masaki Takiguchi, Katsuro Iwase, Seiichi Oyadomari, Motoaki Shichiri, Masataka Mori, Fumihiko Matsuno, Tatsuya Kimura, Eiichi Araki
Publikováno v:
FEBS Letters. 478:141-146
The gene for a transcription factor hepatocyte nuclear factor-4alpha (HNF-4alpha) is responsible for maturity-onset diabetes of the young, type 1. We examined hormonal regulation of the HNF-4alpha gene in the liver. Stimulation of primary-cultured ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d74c2637836ed971293f3968a917d8
https://doi.org/10.1016/s0014-5793(00)01840-8
https://doi.org/10.1016/s0014-5793(00)01840-8
Autor:
Kazuhiko Ishihara, Seiya Shimoda, Kenshi Ichinose, Tanja Nowak, Kenro Nishida, Michiharu Sakakida, Nobuo Nakabayashi, Motoaki Shichiri, Y. Konno
Publikováno v:
Journal of Artificial Organs. 3:39-46
Biocompatibility is important to assure a mild body reaction to an implanted device and its long-term stability and functionality. In diabetes research, subcutaneously implanted glucose monitoring systems need biocompatible surfaces for long-term app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1eb949ac2b850dc8dc67529a072769b
https://doi.org/10.1007/bf02479925
https://doi.org/10.1007/bf02479925
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 7:14-20
We and other groups have recently demonstrated that oxidized low density lipoprotein (Ox-LDL) induces proliferation of macrophages in vitro. Since previous immunohistochemical studies demonstrated that macrophages and macrophage derived foam cells pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208080fc8c5b2c49e5273ac2437e12e1
https://doi.org/10.5551/jat1994.7.14
https://doi.org/10.5551/jat1994.7.14
Autor:
Kohji Matsuda, Kengo Kaneko, Noboru Furukawa, Masakazu Sakai, Takeshi Matsumura, Motoaki Shichiri
Publikováno v:
Journal of Biological Chemistry. 274:37665-37672
We previously demonstrated that the induction of granulocyte/macrophage colony-stimulating factor (GM-CSF) played an important role in oxidized low density lipoprotein (Ox-LDL)-induced macrophage growth as a growth priming factor. The present study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf540efe973338cb1892a22072807be3
https://doi.org/10.1074/jbc.274.53.37665
https://doi.org/10.1074/jbc.274.53.37665