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Autor:
Vialettes, Bernard
Publikováno v:
In Médecine des maladies métaboliques September 2021 15(5):558-562
Autor:
Bernard Vialettes
Publikováno v:
Médecine des Maladies Métaboliques. 15:558-562
Autor:
Yukio Shigeta, Yoshitomo Oka, Kempei Matsuoka, Nigishi Hotta, Takayoshi Toyota, Ryuzo Kawamori, Motoaki Shichiri, Yasuo Akanuma, Nobuo Sakamoto
Publikováno v:
Diabetes Research and Clinical Practice. 77:S263-S268
In order to study a long-term effect along with adverse action of epalrestat, an aldose reductase inhibitor, a randomized, prospective study was conducted over the period of 3 years at 112 facilities. Six hundred and three diabetic patients with medi
Autor:
Yoshitomo Oka, Isao Yoshimura, Motoaki Shichiri, Mitsuyoshi Nakashima, Ryuzo Kawamori, Takayoshi Toyota, Kempei Matsuoka, Nigishi Hotta, Yasuo Akanuma, Nobuo Sakamoto, Yukio Shigeta
Publikováno v:
Diabetes Care. 29:1538-1544
OBJECTIVE—We sought to evaluate the long-term efficacy and safety of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy. RESEARCH DESIGN AND METHODS—Subjects with diabetic neuropathy, median motor nerve conduction veloci
Autor:
Kazuhiko Nakamaru, Kazuya Matsumoto, Eiichi Araki, Noboru Furukawa, Motoaki Shichiri, Tetsuya Shirotani
Publikováno v:
Endocrine Journal. 49:121-130
Autor:
Tetsushi Toyonaga, Yousuke Ebina, Hiroyuki Motoshima, Tetsuya Taguchi, Noboru Furukawa, Kazuaki Yoshizato, Eiichi Araki, Yoshiaki Hirashima, Motoaki Shichiri, Junji Kawashima, Tetsuya Shirotani
Publikováno v:
Biochemical and Biophysical Research Communications. 280:428-434
The liver is a major target organ of insulin and is important for glucose homeostasis. We analyzed the tissue specific regulation of the insulin receptor gene in the liver by studying the cis-acting element and trans-acting factor of the human insuli
Autor:
Takayuki Sasahara, Masakazu Sakai, Yoshichika Anami, Motoaki Shichiri, Toru Takemura, Takeshi Matsumura, Hirofumi Matsuda, Takeshi Biwa, Takeshi Nishikawa
Publikováno v:
Atherosclerosis. 152:347-357
Macrophage-derived foam cells are known to play an essential role in the development and progression of atherosclerotic lesions. Probucol prevents oxidative modification of low-density lipoprotein (LDL) and lowers plasma contents of LDL and high-dens
Autor:
Shoaib Chowdhury, Masaki Takiguchi, Katsuro Iwase, Seiichi Oyadomari, Motoaki Shichiri, Masataka Mori, Fumihiko Matsuno, Tatsuya Kimura, Eiichi Araki
Publikováno v:
FEBS Letters. 478:141-146
The gene for a transcription factor hepatocyte nuclear factor-4alpha (HNF-4alpha) is responsible for maturity-onset diabetes of the young, type 1. We examined hormonal regulation of the HNF-4alpha gene in the liver. Stimulation of primary-cultured ra