Enzyme Catalyzed Formation of CoA Adducts of Fluorinated Hexanoic Acid Analogues using a Long-Chain acyl-CoA Synthetase from Gordonia sp. Strain NB4-1Y.

Autor: Mothersole RG; Department of Chemistry, Thompson Rivers University, 805 TRU Way, Kamloops, British Columbia V2C 0C8, Canada., Mothersole MK; Department of Biological Sciences, Thompson Rivers University, 805 TRU Way, Kamloops, British Columbia V2C 0C8, Canada., Goddard HG; Department of Biological Sciences, Thompson Rivers University, 805 TRU Way, Kamloops, British Columbia V2C 0C8, Canada., Liu J; Department of Civil Engineering, McGill University, 817 Sherbrooke Street West, Montreal, Québec H3A 0C3, Canada., Van Hamme JD; Department of Biological Sciences, Thompson Rivers University, 805 TRU Way, Kamloops, British Columbia V2C 0C8, Canada.

Publikováno v: Biochemistry [Biochemistry] 2024 Sep 03; Vol. 63 (17), pp. 2153-2165. Date of Electronic Publication: 2024 Aug 17.

Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species.

Autor: Mothersole RG; Department of Chemistry, University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna V1V 1V7, Canada., Kolesnikov M; Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver V6T 1Z3, Canada., Chan ACK; Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver V6T 1Z3, Canada., Oduro E; Department of Chemistry, University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna V1V 1V7, Canada., Murphy MEP; Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver V6T 1Z3, Canada., Wolthers KR; Department of Chemistry, University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna V1V 1V7, Canada.

Publikováno v: Biochemistry [Biochemistry] 2022 Jul 05; Vol. 61 (13), pp. 1378-1391. Date of Electronic Publication: 2022 Jun 22.

S224 Presents a Catalytic Trade-off in PLP-Dependent l-Lanthionine Synthase from Fusobacterium nucleatum .

Autor: Mothersole RG; Department of Chemistry, The University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna, British Columbia V1V1V7, Canada., Billett CR; Department of Chemistry, The University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna, British Columbia V1V1V7, Canada., Saini G; Department of Chemistry, The University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna, British Columbia V1V1V7, Canada., Mothersole MK; Department of Chemistry, The University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna, British Columbia V1V1V7, Canada., Darbyshire AL; Department of Chemistry, The University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna, British Columbia V1V1V7, Canada., Wolthers KR; Department of Chemistry, The University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna, British Columbia V1V1V7, Canada.

Publikováno v: Biochemistry [Biochemistry] 2020 Nov 10; Vol. 59 (44), pp. 4250-4261. Date of Electronic Publication: 2020 Oct 28.

Structural insight into the high reduction potentials observed for Fusobacterium nucleatum flavodoxin.

Autor: Mothersole RG; Department of Chemistry, University at the British Columbia, Kelowna, British Columbia, V1V 1V7, Canada., Macdonald M; Department of Chemistry, University at the British Columbia, Kelowna, British Columbia, V1V 1V7, Canada., Kolesnikov M; Department of Microbiology and Immunology, University at the British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada., Murphy MEP; Department of Microbiology and Immunology, University at the British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada., Wolthers KR; Department of Chemistry, University at the British Columbia, Kelowna, British Columbia, V1V 1V7, Canada.

Publikováno v: Protein science : a publication of the Protein Society [Protein Sci] 2019 Aug; Vol. 28 (8), pp. 1460-1472. Date of Electronic Publication: 2019 Jun 19.

Role of active site loop in coenzyme binding and flavin reduction in cytochrome P450 reductase.

Autor: Mothersole RG; Department of Chemistry, University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna, BC, V1V 1V7, Canada., Meints CE; Department of Chemistry, University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna, BC, V1V 1V7, Canada., Louder A; Department of Chemistry, University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna, BC, V1V 1V7, Canada., Wolthers KR; Department of Chemistry, University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna, BC, V1V 1V7, Canada. Electronic address: kirsten.wolthers@ubc.ca.

Publikováno v: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2016 Sep 15; Vol. 606, pp. 111-9. Date of Electronic Publication: 2016 Jul 25.