Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Mothers against decapentaplegic homolog 3"'
Autor:
Muhamad Ansar, Chun-Jung Wang, Yu-Han Wang, Tsung-Hua Shen, Chin-Sheng Hung, Shih-Ching Chang, Ruo-Kai Lin
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7395 (2020)
The incidence and mortality rates of colorectal cancer (CRC) have been high in recent years. Prevention and early detection are crucial for decreasing the death rate. Therefore, this study aims to characterize the alteration patterns of mothers again
Externí odkaz:
https://doaj.org/article/761d08302aff4b9cbdb4d245d91941f3
Publikováno v:
Journal of Biomaterials and Tissue Engineering. 11:1825-1831
This study intends to investigate the mechanism by how microRNA (miRNA)-23b alleviates kidney damage in septic rats. Herein, septic rat model, control group and sham-operated model were set up to assess kidney tissue damage. Tissues were extracted fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aed63daaf3a48355b1f7da9163eeaf9f
https://doi.org/10.1166/jbt.2021.2849
https://doi.org/10.1166/jbt.2021.2849
Publikováno v:
Journal of Biomaterials and Tissue Engineering. 11:697-703
Our study aims to investigate the mechanism whereby microRNA (miRNA)-23b alleviates kidney damage in septic rats. Herein, we set up septic rat model, control group and sham-operated model to evaluate the kidney tissue damage. The glomerular mesangial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c57d68b279730799ab9dcdf40968a49
https://doi.org/10.1166/jbt.2021.2745
https://doi.org/10.1166/jbt.2021.2745
Autor:
Xian Zeng, Dianwen Ju, Jiajun Fan, Yichen Wang, Jinghui Zhang, Jingyun Luan, Kai Yin, Mingming Nie
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 609-620 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 609-620 (2021)
The Hedgehog (HH) signaling pathway plays important roles in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment (TME). Aberrant HH signaling activation may accelerate the growth of gastrointestinal tumors and lead to tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9591fe5f71a6d93ff75c586983adcb
https://doi.org/10.1016/j.apsb.2020.10.022
https://doi.org/10.1016/j.apsb.2020.10.022
Autor:
Julia Kistner, Mariam Yazdanyar, Artur Lichtenberg, Ann Kathrin Bergmann, Payam Akhyari, Sarah Saradar, Alexander Jenke, Melanie Vera Rötepohl, Agunda Chekhoeva
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 319:H1123-H1141
Calcific aortic valve disease (CAVD) is characterized by valvular fibrosis and calcification and driven by differentiating valvular interstitial cells (VICs). Expression data from patient biopsies suggest that transforming growth factor (TGF)-β1 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282781cc34a831460757bb222f7b743f
https://doi.org/10.1152/ajpheart.00651.2019
https://doi.org/10.1152/ajpheart.00651.2019
Autor:
Bixiang Zhang, Xiaoping Chen, Xuewu Zhang, Wei Dong, Liang Chu, Qiumeng Liu, Zhibin Liao, He Zhu, Xiaolong Tan, Hui-fang Liang, Hongwei Zhang, Zhanguo Zhang, Peng Zhu, Zeyang Ding, Keshuai Dong, Lin Chen, Pran K. Datta, Xun Lu
Publikováno v:
Hepatology. 72:997-1012
BACKGROUND AND AIMS Transforming growth factor beta (TGF-β) suppresses early stages of tumorigenesis, but contributes to the migration and metastasis of cancer cells. However, the role of TGF-β signaling in invasive prometastatic hepatocellular car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192787dea6f5209c88b22fbf366bd333
https://doi.org/10.1002/hep.31104
https://doi.org/10.1002/hep.31104
Publikováno v:
International Journal of Molecular Medicine
miRNA-135a-5p upregulation has been identified in renal fibrosis in diabetic nephropathy (DN) with an incompletely known mechanism. Previous data showed that Sirtuin 1 (SIRT1) serves as a novel therapeutic target for DN and interact with the transfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c55742efca40e3af4e0b7000ea07b3
https://doi.org/10.3892/ijmm.2020.4647
https://doi.org/10.3892/ijmm.2020.4647
Publikováno v:
The FASEB Journal. 33:9279-9290
Diabetes nephropathy (DN) is characterized by abnormal interactions between kidney-infiltrating macrophages and glomerular mesangial cells. Recently, a novel cell-cell communication mediated by exosomes has gained attention. Exosomes are membrane-bou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3224102aeec97ca5789290a75494ce3f
https://doi.org/10.1096/fj.201802427rrr
https://doi.org/10.1096/fj.201802427rrr
Publikováno v:
Molecular Medicine Reports
Lung cancer is a complex disease involving multiple genetic and phenotypic alterations. As a histone modification enzyme, protein‑arginine deiminase type‑4 (PADI4) and its downstream signaling have been studied in the progression of a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6983661af6b211ee90b4e61e2d6b7a
http://europepmc.org/articles/PMC6423585
http://europepmc.org/articles/PMC6423585
Autor:
Jian-Xin Shi, You-Wei Wang, Chong Chen, Yue Tu, Xiu Fan, Xiao-Hong Li, Xiao-Li Jia, Feng Chen, Lin Xu, Jing Wang, Nan Hu
Publikováno v:
Brain research. 1775
Traumatic brain injury (TBI) is a brain injury resulting from blunt mechanical external forces, which is a crucial public health and socioeconomic problem worldwide. TBI is one of the leading causes of death or disability. The primary injury of TBI i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4004a1358abbf040a66cc209242edec
https://pubmed.ncbi.nlm.nih.gov/34793756
https://pubmed.ncbi.nlm.nih.gov/34793756