Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mostafa Nakach"'
Autor:
Manon Ripoll, Elian Martin, Mathilde Enot, Oscar Robbe, Chiara Rapisarda, Marie-Claire Nicolai, Aurélie Deliot, Patrick Tabeling, Jean-René Authelin, Mostafa Nakach, Pierre Wils
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Lipid nanoparticles (LNPs) for RNA and DNA delivery have attracted considerable attention for their ability to treat a broad range of diseases and to vectorize mRNA for COVID vaccines. LNPs are produced by mixing biomolecules and lipids, whi
Externí odkaz:
https://doaj.org/article/08f3075aaadd4498a6d006c52044a091
Autor:
Mostafa Nakach, Chloe Amine, Charlotte Pellet, Fethi Bensaid, Jean-René Authelin, Pierre Wils
Publikováno v:
Journal of pharmaceutical sciences. 111(10)
Fillfinish manufacturing processes of biologics drug product involve multiple unit operations. In particular they often include a mixing step to reduce non-uniformities in fluids by eliminating gradients of concentration and pH may occur during freez
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc96eae8442f40684e5155fdf2f7e85
https://pubmed.ncbi.nlm.nih.gov/35577115
https://pubmed.ncbi.nlm.nih.gov/35577115
Autor:
Stephanie Greco, Cathrin Bernhardt, Mostafa Nakach, Otmar Klingler, Firas Bahloul, Jean-Rene Authelin
Publikováno v:
PDA journal of pharmaceutical science and technology. 75(1)
The freezing of biologics has been widely studied from the physical chemistry point of view, for instance in terms of cryo-concentration, excipient crystallization, pH swing, potential protein denaturation, etc. In contrast, considerations on the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a4cf54b912c4bfeeff7ea5c5db7f15
https://pubmed.ncbi.nlm.nih.gov/32817319
https://pubmed.ncbi.nlm.nih.gov/32817319
Autor:
Ranjita Shegokar, Mostafa Nakach
Nowadays research effort on nanotechnologies for pharmaceutical has shown that many nanodrug delivery systems (including nanocrystalline suspension, emulsion, liposomes, polymeric nanoparticles, lipid nanoparticles) can be used as enabling technologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f160115edcb80d6d7f3ae4683a52c58
https://doi.org/10.1016/b978-0-12-821222-6.00004-x
https://doi.org/10.1016/b978-0-12-821222-6.00004-x
Autor:
Hend Abd-Allah, Sara M. Abdel Samie, Mona M.A. Abdel-Mottaleb, Abid Riaz Ahmed, Akash Chavrasiya, Yanping Chen, João Dias-Ferreira, Diana Diaz-Arévalo, Sachin Dubey, Alessandra Durazzo, Thomas Dürig, Riham I. El-Gogary, Muhammad Irfan, Nirmal Jayabalan, Anđelka B. Kovačević, Dharmesh Mehta, Joana Portugal Mota, Mostafa Nakach, Maha Nasr, Ridahunlang Nongkhlaw, Parameswar Patra, Antonello Santini, Ahmad Abdul-Wahhab Shahba, Ranjita Shegokar, Vaibhav Sihorkar, Sarabjit Singh, Eliana B. Souto, Haiyan Wang, Yongyong Yan, Mingtao Zeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c82dcc29bf3a54d63a5c4155778ff3e
https://doi.org/10.1016/b978-0-12-821222-6.09995-4
https://doi.org/10.1016/b978-0-12-821222-6.09995-4
Jet milling is frequently used in pharmaceutical industry to achieve different objectives. It can be used as enabling technology to overcome poor water solubility linked to hydrophobic active of pharmaceutical ingredient (API) by reducing the particl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b978082fca28d7317ed18b85c636e164
Publikováno v:
International journal of pharmaceutics. 547(1-2)
Currently, the two technologies primarily used for the manufacturing of nano-crystalline suspensions using top down process (i.e. wet milling) are high pressure homogenization (HPH) and stirred bead milling (SBM). These two technologies are based upo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::917787149c03e8e1adfda424bf8a6fb1
https://pubmed.ncbi.nlm.nih.gov/29787896
https://pubmed.ncbi.nlm.nih.gov/29787896
Publikováno v:
Journal of pharmaceutical sciences. 106(7)
Stirred media milling is the main technology for producing colloidal nanocrystalline suspensions. A number of studies have been reported on the effect of different operating parameters for lab, pilot, and industrial scales. However, typical milling t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412e8a509307cf1707c813231b46e759
https://pubmed.ncbi.nlm.nih.gov/28302540
https://pubmed.ncbi.nlm.nih.gov/28302540
Autor:
Mostafa Nakach, Jean-Rene Authelin
Publikováno v:
Pharmaceutical Nanotechnology: Innovation and Production ISBN: 9783527800681
Pharmaceutical Nanotechnology: Innovation and Production
Pharmaceutical Nanotechnology: Innovation and Production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9c6b9f5e415bc8460924fdfb78af6c2
https://doi.org/10.1002/9783527800681.ch12
https://doi.org/10.1002/9783527800681.ch12
Autor:
Tharwat Tadros, Mostafa Nakach, Laurence Galet, Cecile Voignier, Alain Chamayou, Jean-Rene Authelin
Publikováno v:
International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2016, 506 (1-2), p. 320-331. ⟨10.1016/j.ijpharm.2016.04.043⟩
International Journal of Pharmaceutics, Elsevier, 2016, 506 (1-2), p. 320-331. ⟨10.1016/j.ijpharm.2016.04.043⟩
International audience; The small particle size of nano-crystalline suspensions can be responsible for their physical instability during drug product preparation (downstream processing), storage and administration. For that purpose, the commercial fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39aaa2cd4260df6edaa43807c1b6c4e2
https://hal.archives-ouvertes.fr/hal-01593327/document
https://hal.archives-ouvertes.fr/hal-01593327/document