Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Mostafa A. Rabie"'
Autor:
Ibrahim F. Abo-Elmagd, Amr M. Mahmoud, Medhat A. Al-Ghobashy, Marianne Nebsen, Mostafa A. Rabie, Ahmed F. Mohamed, Lamiaa A. Ahmed, Nesrine S. El Sayed, Reem K. Arafa, Robert Todd, Salwa A. Elgebaly
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-12 (2024)
Abstract The cardioprotective drug cyclocreatine phosphate has been awarded Food and Drug Administration-orphan drug designation for the prevention of ischemic injury to enhance cardiac graft recovery and survival in heart transplantation. Cyclocreat
Externí odkaz:
https://doaj.org/article/f6c16d8113b64c19a794e83024366cba
Autor:
Alaa Sirwi, Nesrine S. El-Sayed, Dina A.I. Albadawi, Abdulrahman E. Koshak, Sabrin R.M. Ibrahim, Gamal A. Mohamed, Hossam M. Abdallah, Mostafa A. Rabie
Publikováno v:
Scientific African, Vol 26, Iss , Pp e02470- (2024)
Costunolide (COST), a sesquiterpene lactone, has demonstrated promising potential in molecular docking studies targeting key proteins associated with Parkinson's disease (PD), particularly AMP-activated protein kinase (AMPK) and sirtuin-1 (SIRT1). Bu
Externí odkaz:
https://doaj.org/article/5fcd520b81af4888a9e47a3dc30bde7f
Autor:
Salwa A. Elgebaly, Charles Van Buren, Robert Todd, Robert Poston, Reem K. Arafa, Nashwa El-Khazragy, Donald Kreutzer, Mostafa A. Rabie, Ahmed F. Mohamed, Lamiaa A. Ahmed, Nesrine S. El Sayed
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 453 (2023)
Irreversible myocardial injury causes the exhaustion of cellular adenosine triphosphate (ATP) contributing to heart failure (HF). Cyclocreatine phosphate (CCrP) was shown to preserve myocardial ATP during ischemia and maintain cardiac function in var
Externí odkaz:
https://doaj.org/article/7de2e15602934279973463c318003fc8
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
GTP cyclohydrolase I (GTPCH I) is the rate-limiting enzyme for tetrahydrobiopterin (BH4) biosynthesis; the latter is an essential factor for iNOS activation that contributes neuronal loss in Huntington’s disease (HD). The aim of the study was to in
Externí odkaz:
https://doaj.org/article/a14cdf26ccf84879ab2a715ba81a98d7
Autor:
Ahmed S. Kamel, Ahmed F. Mohamed, Mostafa A. Rabie, Marwa E. Elsherbiny, Kawkab A. Ahmed, Mahmoud M. Khattab, Noha F. Abdelkader
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 251 (2022)
Though quinoline anti-infective agents-associated neurotoxicity has been reported in the early 1970s, it only recently received regulatory recognition. In 2019, the European Medicines Agency enforced strict use for quinoline antibiotics. Thus, the cu
Externí odkaz:
https://doaj.org/article/01296fe371764e2eab422bc059459954
Publikováno v:
Drug Development Research.
Publikováno v:
International immunopharmacology. 115
Multiple sclerosis (MS) is a disabling neurodegenerative disease that causes demyelination and axonal degeneration of the central nervous system. Current treatments are partially effective in managing MS relapses and have a negligible impact on treat
Autor:
Mostafa A. Rabie, Rabab H. Sayed, Jagadeesh K. Venkatesan, Henning Madry, Magali Cucchiarini, Nesrine S. El Sayed
Publikováno v:
Toxicology and applied pharmacology.
Osteoarthritis (OA) is a chronic debilitating degenerative disorder leading to structural, and functional anomaly of the joint. The present study tests the hypothesis that overexpression of the basic fibroblast growth factor (FGF-2) via direct rAAV-m
Publikováno v:
Chemico-biological interactions. 369
Huntington's disease (HD) is an inherited neurodegenerative disease characterized by progressive motor, behavioral, and cognitive impairments. Intrastriatal injection of 3- nitropropionic acid (3NP) was used to induce HD-like symptoms by inhibiting s
Autor:
Rabab H. Sayed, Mostafa A. Rabie
Publikováno v:
Handbook of Substance Misuse and Addictions ISBN: 9783030679286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144b0a97ea8bf237eec7c86ab7b9e681
https://doi.org/10.1007/978-3-030-67928-6_149-1
https://doi.org/10.1007/978-3-030-67928-6_149-1