Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mostafa A, Elhendawy"'
Autor:
Mona M. Geweda, Chandrani G. Majumdar, Malorie N. Moore, Mostafa A. Elhendawy, Mohamed M. Radwan, Suman Chandra, Mahmoud A. ElSohly
Publikováno v:
Journal of Cannabis Research, Vol 6, Iss 1, Pp 1-9 (2024)
Abstract Background Cannabis policies have changed drastically over the last few years with many states enacting medical cannabis laws, and some authorizing recreational use; all against federal laws. As a result, cannabis products are marketed in di
Externí odkaz:
https://doaj.org/article/06b9e722203f49caa374418f004e0884
Autor:
Ahmed A. Gaber, Mohamed Sobhy, Abdallah Turky, Hanan Gaber Abdulwahab, Ahmed A. Al-Karmalawy, Mostafa. A. Elhendawy, Mohamed. M. Radwan, Eslam B. Elkaeed, Ibrahim M. Ibrahim, Heba S. A. Elzahabi, Ibrahim H. Eissa
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2283-2303 (2022)
New 1H-pyrazolo[3,4-d]pyrimidine derivatives were designed and synthesised to act as epidermal growth factor receptor inhibitors (EGFRIs). The synthesised derivatives were assessed for their in vitro anti-proliferative activities against A549 and HCT
Externí odkaz:
https://doaj.org/article/9c78e6d27f724d00b86fc7168f045834
Autor:
Chandrani G. Majumdar, Mahmoud A. ElSohly, Elsayed A. Ibrahim, Mostafa A. Elhendawy, Donald Stanford, Suman Chandra, Amira S. Wanas, Mohamed M. Radwan
Publikováno v:
Molecules, Vol 28, Iss 23, p 7710 (2023)
In recent years, cannabis has been proposed and promoted not only as a medicine for the treatment of a variety of illnesses, but also as an industrial crop for different purposes. Being an agricultural product, cannabis inflorescences may be contamin
Externí odkaz:
https://doaj.org/article/c835abf93ade4e94b4f9e49429d36b92
Autor:
Ahmed M. Metwaly, Ibrahim H. Eissa, Mostafa A. Elhendawy, Ahmed B.M. Mehany, Khaled El-Adl, Mahmoud A. ElSohly, Helmy Sakr, Reda G. Yousef, Hamada S. Abulkhair, Mohamed M. Radwan
Publikováno v:
New Journal of Chemistry. 45:16949-16964
Eleven new quinoxaline derivatives were designed and synthesized as modified VEGFR-2 inhibitors of our previous work. The synthesized compounds were tested against three human cancer cell lines (HepG-2, MCF-7 and HCT-116). Compounds 11g, 11e and 11c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37f1e24f7291622452bcce73a55793d6
https://doi.org/10.1039/d1nj02509k
https://doi.org/10.1039/d1nj02509k
Autor:
Adam M, Gilmore, Mostafa A, Elhendawy, Mohamed M, Radwan, Linda H, Kidder, Amira S, Wanas, Murrell, Godfrey, Jana B, Hildreth, A Edward, Robinson, Mahmoud A, ElSohly
Publikováno v:
Cannabis and cannabinoid research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e09a6633915cf300d7f733056af3e40
https://pubmed.ncbi.nlm.nih.gov/35486823
https://pubmed.ncbi.nlm.nih.gov/35486823
Autor:
Mostafa A. Elhendawy, Amira S. Wanas, Mahmoud A. ElSohly, Mohamed M. Radwan, N. A. Azzaz, ElShahat S Toson
Publikováno v:
Medical Cannabis and Cannabinoids. 1:104-111
The chemical study of Cannabis sativa roots led to the isolation and identification of 10 compounds. Their chemical structures were unambiguously established on the basis of 1D and 2D NMR spectroscopy and mass spectrometry as friedelan-3-one (1), epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab5a0e4e96165a347906dedb6b9bf1bf
https://doi.org/10.1159/000495582
https://doi.org/10.1159/000495582
Autor:
Mahmoud Rashed, Ahmed M. Metwaly, Helmy Sakr, Abdou El-Sharkawy, Hazem A. Mahdy, Mahmoud A. ElSohly, Mostafa A. Elhendawy, Ibrahim H. Eissa, Mohamed M. Radwan, Rezk R. Ayyad, Abdel-Ghany A. El-Helby, Amany Belal, Mohamed M. Khalifa
Publikováno v:
Bioorganic chemistry. 103
Herein we report the design and synthesis of a new series of phthalazine derivatives as Topo II inhibitors and DNA intercalators. The synthesized compounds were in vitro evaluated for their cytotoxic activities against HepG-2, MCF-7 and HCT-116 cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec832eb98121b26b90497027f7f5fba8
https://pubmed.ncbi.nlm.nih.gov/32882440
https://pubmed.ncbi.nlm.nih.gov/32882440
Autor:
Mohamed M. Radwan, Ahmed B.M. Mehany, Ahmed M. Metwaly, Mostafa A. Elhendawy, Abdelrahman M. Yassin, Mahmoud A. ElSohly, Mohamed-Kamal Ibrahim, Ibrahim H. Eissa, Elsayed E. Hafez, Nehal M. El-Deeb, Amany Belal, Mohammed S Taghour
Publikováno v:
European Journal of Medicinal Chemistry. 155:117-134
New series of [1,2,4]triazolo [4,3-a]quinoxaline and bis([1,2,4]triazolo)[4,3-a:3′,4′-c]quinoxaline derivatives have been designed, synthesized and biologically evaluated for their cytotoxic activities against three tumor cell lines (HePG-2, Hep-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471d13d02ac23bc77e7700ab8db7efa0
https://doi.org/10.1016/j.ejmech.2018.06.004
https://doi.org/10.1016/j.ejmech.2018.06.004
Autor:
Ahmed B.M. Mehany, Mohamed M. Radwan, Mahmoud A. ElSohly, Hamada S. Abulkhair, Ahmed M. Metwaly, Mostafa A. Elhendawy, Ibrahim H. Eissa, Helmy Sakr, Reda G. Yousef, Khaled El-Adl
Publikováno v:
Bioorganic Chemistry. 114:105105
VEGF/VEGFR2 pathway is the crucial therapeutic target in the treatment of cancer. So that, a new series of quinoxaline-2(1H)-one derivatives were designed and synthesized. The synthesized compounds were tested against three human cancer cell lines (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0150a9ae9b0f97cb29f1127d122b67
https://doi.org/10.1016/j.bioorg.2021.105105
https://doi.org/10.1016/j.bioorg.2021.105105
Autor:
Hazem A. Mahdy, Mahmoud A. ElSohly, Ahmed B.M. Mehany, Amany Belal, Mohammed S Taghour, Souad A. El-Metwally, Mostafa A. Elhendawy, Ibrahim H. Eissa, Mohamad E. El‐Sawah, Mohamed M. Radwan, Khaled El-Adl, Ahmed M. Metwaly, Kamal M. El-Gamal, Rezk R. Ayyad
Publikováno v:
Archiv der Pharmazie. 352(11)
In continuation of our previous work on the design and synthesis of topoisomerase II (Topo II) inhibitors and DNA intercalators, a new series of quinoxaline derivatives were designed and synthesized. The synthesized compounds were evaluated for their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae649f761a34f488c93c0c9ac3eff15
https://pubmed.ncbi.nlm.nih.gov/31463953
https://pubmed.ncbi.nlm.nih.gov/31463953