Bifidobacteria metabolize lactulose to optimize gut metabolites and prevent systemic infection in patients with liver disease.

Autor: Odenwald MA; Department of Medicine, Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Chicago, IL, USA. matthew.odenwald@uchicagomedicine.org., Lin H; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Lehmann C; Department of Medicine, Section of Infectious Diseases and Global Health, University of Chicago, Chicago, IL, USA., Dylla NP; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Cole CG; Duchossois Family Institute, University of Chicago, Chicago, IL, USA.; Department of Microbiology, University of Chicago, Chicago, IL, USA., Mostad JD; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Pappas TE; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Ramaswamy R; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Moran A; Department of Pathology, University of Chicago, Chicago, IL, USA., Hutchison AL; Department of Medicine, Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Chicago, IL, USA., Stutz MR; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Cook County Health, Chicago, IL, USA., Dela Cruz M; Section of Cardiology, Department of Medicine, University of Chicago, Chicago, IL, USA., Adler E; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Boissiere J; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Khalid M; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Cantoral J; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Haro F; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Oliveira RA; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Waligurski E; Duchossois Family Institute, University of Chicago, Chicago, IL, USA.; Department of Microbiology, University of Chicago, Chicago, IL, USA., Cotter TG; Division of Digestive and Liver Diseases, UT Southwestern Medical Center, Dallas, TX, USA., Light SH; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Beavis KG; Department of Pathology, University of Chicago, Chicago, IL, USA., Sundararajan A; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Sidebottom AM; Duchossois Family Institute, University of Chicago, Chicago, IL, USA., Reddy KG; Department of Medicine, Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Chicago, IL, USA., Paul S; Department of Medicine, Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Chicago, IL, USA., Pillai A; Department of Medicine, Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Chicago, IL, USA., Te HS; Department of Medicine, Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Chicago, IL, USA., Rinella ME; Department of Medicine, Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Chicago, IL, USA., Charlton MR; Department of Medicine, Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Chicago, IL, USA., Pamer EG; Duchossois Family Institute, University of Chicago, Chicago, IL, USA. egpamer@bsd.uchicago.edu.; Department of Medicine, Section of Infectious Diseases and Global Health, University of Chicago, Chicago, IL, USA. egpamer@bsd.uchicago.edu.; Department of Microbiology, University of Chicago, Chicago, IL, USA. egpamer@bsd.uchicago.edu., Aronsohn AI; Department of Medicine, Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Chicago, IL, USA.

Publikováno v: Nature microbiology [Nat Microbiol] 2023 Nov; Vol. 8 (11), pp. 2033-2049. Date of Electronic Publication: 2023 Oct 16.