Zobrazeno 1 - 10
of 1 012
pro vyhledávání: '"Mossy fiber (hippocampus)"'
Autor:
Kenji Sakimura, Ramos Cc, Pablo E. Castillo, Miwako Yamasaki, Stefano Lutzu, Yuchio Yanagawa, Masahiko Watanabe, Susumu Tomita
Publikováno v:
J Neurosci
Mossy cells (MCs) of the dentate gyrus (DG) are key components of an excitatory associative circuit established by reciprocal connections with dentate granule cells (GCs). MCs are implicated in place field encoding, pattern separation and novelty det
Aberrant hippocampal mossy fibers in temporal lobe epilepsy target excitatory and inhibitory neurons
Publikováno v:
Epilepsia. 62:2539-2550
Objective The pathoanatomical correlate of temporal lobe epilepsy is hippocampal sclerosis, characterized by selective neuronal death of mossy cells in the hilus and of pyramidal cells in cornu ammonis 1. Although granule cells survive, they lose mos
Publikováno v:
Brain Stimulation, Vol 14, Iss 4, Pp 771-779 (2021)
Brain Stimul
Brain Stimul
Background Transcranial direct current stimulation (tDCS) provides a noninvasive polarity-specific constant current to treat epilepsy, through a mechanism possibly involving excitability modulation and neural oscillation. Objective To determine wheth
Autor:
Armin Brandt, Soroush Doostkam, Carola A. Haas, Ute Häussler, Josef Zentner, Jürgen Beck, Thomas M. Freiman, Christian Scheiwe, Barbara Puhahn-Schmeiser
Publikováno v:
Hippocampus. 31:580-592
Hippocampal sclerosis (HS) in Temporal Lobe Epilepsy (TLE) shows neuronal death in cornu ammonis (CA)1, CA3, and CA4. It is known that granule cells and CA2 neurons survive and their axons, the mossy fibers (MF), lose their target cells in CA3 and CA
Autor:
Ting-Ting Du, Ying-Chuan Chen, Guan-Yu Zhu, De-Feng Liu, Yu-Ye Liu, Tian-Shuo Yuan, Xin Zhang, Jian-Guo Zhang, Ning-Ning Wang.
Publikováno v:
Chinese Medical Journal, Vol 134, Iss 3, Pp 326-333 (2021)
Chinese Medical Journal
Chinese Medical Journal
Background. Anterior thalamic nuclei (ATN) deep brain stimulation (DBS) is an effective method of controlling epilepsy, especially temporal lobe epilepsy. Mossy fiber sprouting (MFS) plays an indispensable role in the pathogenesis and progression of
Autor:
Ernesto Griego, Emilio J. Galván
Publikováno v:
Neuroscience. 456:95-105
Metabotropic glutamate receptors (mGluRs) are a group of G-protein-coupled receptors that exert a broad array of modulatory actions at excitatory synapses of the central nervous system. In the hippocampus, the selective activation of the different mG
Autor:
Thomas J. Pisano, Amanda E. Haye, Brandy A. Briones, Miah N. Pitcher, Heather A. Cameron, Esteban A. Engel, Elizabeth Gould, Emma J. Diethorn
Publikováno v:
Hippocampus
Adult-born granule cells (abGCs) integrate into the hippocampus and form connections with dentate gyrus parvalbumin-positive (PV+) interneurons, a circuit important for modulating plasticity. Many of these interneurons are surrounded by perineuronal
Autor:
Jeffrey N. Savas, Vasily Rybakin, Nuno Apóstolo, Joris de Wit, Natalia V. Gounko, Samuel N. Smukowski, Jolijn ten Bos, Laura Trobiani, Davide Comoletti, Giuseppe Condomitti, Jeroen Vanderlinden, Sybren Portegies, Keimpe D. Wierda, Kristel M. Vennekens
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Nature Communications
Nature Communications
Excitatory and inhibitory neurons are connected into microcircuits that generate circuit output. Central in the hippocampal CA3 microcircuit is the mossy fiber (MF) synapse, which provides powerful direct excitatory input and indirect feedforward inh
Autor:
Desiree R Seib, Alyssa M Ash, Matthew B. Cooke, Sharon S. Kwan, Timothy P. O'Leary, Delane F Espinueva, Shaina P. Cahill, Jason S. Snyder, John Darby Cole
Publikováno v:
J Neurosci
During immature stages, adult-born neurons pass through critical periods for survival and plasticity. It is generally assumed that by 2 months of age adult-born neurons are mature and equivalent to the broader neuronal population, raising questions o
Autor:
Timothy P. O'Leary, Kathryn Darby, Bonnie H. Lee, Delane F Espinueva, Cypress Knudson, Desiree R Seib, Baran Askari, Jason S. Snyder, Alyssa M Ash
Adult hippocampal neurogenesis has been implicated in the spatial processing functions of the hippocampus but ablating neurogenesis does not consistently lead to behavioral deficits in spatial tasks. Parallel studies have shown that adult-born neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55b1063f15a441c35c8b05ce609df8b9
https://doi.org/10.1101/2021.10.27.466135
https://doi.org/10.1101/2021.10.27.466135