Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Mossab Y. Saeed"'
Autor:
Borami Shin, MD, Mossab Y. Saeed, MD, Jesse J. Esch, MD, Alvise Guariento, MD, David Blitzer, MD, Kamila Moskowitzova, MD, Giovanna Ramirez-Barbieri, MD, Arzoo Orfany, MD, Jerusha K. Thedsanamoorthy, BA, Douglas B. Cowan, PhD, James A. Inkster, PhD, Erin R. Snay, BRS, Steven J. Staffa, MS, Alan B. Packard, PhD, David Zurakowski, PhD, Pedro J. del Nido, MD, James D. McCully, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 871-888 (2019)
Summary: Mitochondrial dysfunction is the determinant insult of ischemia-reperfusion injury. Autologous mitochondrial transplantation involves supplying one’s healthy mitochondria to the ischemic region harboring damaged mitochondria. The authors u
Externí odkaz:
https://doaj.org/article/babe002306fd4682ab8fe8ad9fed1494
Autor:
Lucy Hu, Jean Bonnemain, Mossab Y. Saeed, Manisha Singh, Diego Quevedo Moreno, Nikolay V. Vasilyev, Ellen T. Roche
Publikováno v:
Nature Biomedical Engineering. 7:110-123
Severe diaphragm dysfunction can lead to respiratory failure and to the need for permanent mechanical ventilation. Yet permanent tethering to a mechanical ventilator through the mouth or via tracheostomy can hinder a patient’s speech, swallowing ab
Autor:
Victor S. Alemany, Rio Nomoto, Mossab Y. Saeed, Aybuke Celik, William L. Regan, Gregory S. Matte, Dominic P. Recco, Sitaram M. Emani, Pedro J. Del Nido, James D. McCully
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery.
Autor:
Kimberlee Gauvreau, Peter E. Hammer, Isaac Wamala, Mossab Y Saeed, Pedro J. del Nido, Nikolay V. Vasilyev, Daniel Bautista-Salinas, Sunil J. Ghelani
Publikováno v:
Interact Cardiovasc Thorac Surg
OBJECTIVES We have previously shown in experimental settings that a leaflet foldoplasty device reduces redundant leaflet area to re-establish mitral valve (MV) coaptation. The current study investigates the in vivo device retention and functional dur
Autor:
Daniel Bautista-Salinas, Steven J. Staffa, Christopher J. Payne, Conor J. Walsh, Mossab Y Saeed, Thomas Thalhofer, Pedro J. del Nido, Isaac Wamala, David Van Story, Sunil J. Ghelani, Nikolay V. Vasilyev
Publikováno v:
Cardiovascular Engineering and Technology. 13:120-128
Purpose In clinical practice, many patients with right heart failure (RHF) have elevated pulmonary artery pressures and increased afterload on the right ventricle (RV). In this study, we evaluated the feasibility of RV augmentation using a soft robot
Autor:
Gregory A. Wyant, Wenyu Yu, IIias P. Doulamis, Rio S. Nomoto, Mossab Y. Saeed, Thomas Duignan, James D McCully, William G. Kaelin
Publikováno v:
Science
Kynurenic acid (KynA) is tissue protective in cardiac, cerebral, renal, and retinal ischemia models, but the mechanism is unknown. KynA can bind to multiple receptors, including the aryl hydrocarbon receptor, the a7 nicotinic acetylcholine receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d5ffce25df19791b07b7daf072a697
https://europepmc.org/articles/PMC9639781/
https://europepmc.org/articles/PMC9639781/
Autor:
Ilias P. Doulamis, Supreet P. Marathe, Nicholas A. Oh, Mossab Y. Saeed, Angelika Muter, Pedro J. del Nido, Meena Nathan
Publikováno v:
World journal for pediatriccongenital heart surgery. 13(2)
Background: Dextro transposition of the great arteries (d-TGA) is the most common critical congenital cardiac defect surgically treated in the neonatal period by arterial switch operation (ASO). Major aortopulmonary collaterals (MAPCAs) can be presen
Autor:
David M. Hoganson, James D. McCully, Takashi Kido, Alvise Guariento, Ilias P. Doulamis, Sitaram M. Emani, William Regan, Thomas Duignan, Mossab Y Saeed, Pedro J. del Nido, Gregory S. Matte, Francis Fynn-Thompson
Publikováno v:
The Journal of Heart and Lung Transplantation. 39:1279-1288
Purpose Donation after circulatory death (DCD) offers an additional source of cardiac allografts, potentially allowing expansion of the donor pool. In this study, we investigated the efficacy of mitochondrial transplantation to improve myocardial fun
Autor:
David Zurakowski, James D. McCully, Thomas V. Rousselle, Viktoria Weixler, Isaac E. Stillman, Takashi Kido, David Blitzer, James A. H. Inkster, Alvise Guariento, Amandeep Bajwa, Mossab Y Saeed, Arzoo Orfany, Thomas Duignan, Erin Snay, Ilias P. Doulamis, Samir M. Parikh, Alan B. Packard, Pedro J. del Nido, Borami Shin
Publikováno v:
Am J Physiol Renal Physiol
Acute kidney injury is a common clinical disorder and one of the major causes of morbidity and mortality in the postoperative period. In this study, the safety and efficacy of autologous mitochondrial transplantation by intra-arterial injection for r
Autor:
Lucy, Hu, Jean, Bonnemain, Mossab Y, Saeed, Manisha, Singh, Diego, Quevedo Moreno, Nikolay V, Vasilyev, Ellen T, Roche
Publikováno v:
Nature biomedical engineering.
Severe diaphragm dysfunction can lead to respiratory failure and to the need for permanent mechanical ventilation. Yet permanent tethering to a mechanical ventilator through the mouth or via tracheostomy can hinder a patient's speech, swallowing abil