An RNA-based system to study hepatitis B virus replication and evaluate antivirals.

Autor: Yu Y; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Schneider WM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Kass MA; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.; Department of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany., Michailidis E; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Acevedo A; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Pamplona Mosimann AL; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Bordignon J; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Koenig A; Infectious Diseases Research Unit, GSK, Upper Providence, PA 19426, USA., Livingston CM; Infectious Diseases Research Unit, GSK, Upper Providence, PA 19426, USA., van Gijzel H; Computational Biology, Genome Sciences, GSK, Stevenage, UK., Ni Y; German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany., Ambrose PM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.; Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA., Freije CA; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Zhang M; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Zou C; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.; Division of Gastroenterology and Hepatology, Weill Cornell Medical College, New York, NY 10065, USA., Kabbani M; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Quirk C; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Jahan C; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Wu X; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Urban S; Department of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany.; German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany., You S; Infectious Diseases Research Unit, GSK, Upper Providence, PA 19426, USA., Shlomai A; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., de Jong YP; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.; Division of Gastroenterology and Hepatology, Weill Cornell Medical College, New York, NY 10065, USA., Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.

Publikováno v: Science advances [Sci Adv] 2023 Apr 14; Vol. 9 (15), pp. eadg6265. Date of Electronic Publication: 2023 Apr 12.

Isolation of dengue virus serotype 4 genotype II from a patient with high viral load and a mixed Th1/Th17 inflammatory cytokine profile in South Brazil.

Autor: Kuczera D; Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fiocruz, Curitiba, PR, Brazil., Bavia L; Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fiocruz, Curitiba, PR, Brazil., Mosimann AL; Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fiocruz, Curitiba, PR, Brazil., Koishi AC; Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fiocruz, Curitiba, PR, Brazil., Mazzarotto GA; Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fiocruz, Curitiba, PR, Brazil., Aoki MN; Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fiocruz, Curitiba, PR, Brazil., Mansano AM; Secretaria Municipal de Saúde de Cambé, Cambé, PR, Brazil., Tomeleri EI; Secretaria Municipal de Saúde de Cambé, Cambé, PR, Brazil., Costa Junior WL; Secretaria Municipal de Saúde de Cambé, Cambé, PR, Brazil., Miranda MM; Laboratório de Imunoparasitologia Experimental, Universidade Estadual de Londrina, Londrina, PR, Brazil., Lo Sarzi M; Secretaria Municipal de Saúde de Cambé, Cambé, PR, Brazil., Pavanelli WR; Laboratório de Imunoparasitologia Experimental, Universidade Estadual de Londrina, Londrina, PR, Brazil., Conchon-Costa I; Laboratório de Imunoparasitologia Experimental, Universidade Estadual de Londrina, Londrina, PR, Brazil., Duarte Dos Santos CN; Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fiocruz, Curitiba, PR, Brazil. clsantos@fiocruz.br., Bordignon J; Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fiocruz, Curitiba, PR, Brazil. julianobordignon@fiocruz.br.

Publikováno v: Virology journal [Virol J] 2016 Jun 06; Vol. 13, pp. 93. Date of Electronic Publication: 2016 Jun 06.

First report of autochthonous transmission of Zika virus in Brazil.

Autor: Zanluca C; Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fundação Oswaldo Cruz, Curitiba, PR, Brasil., Melo VC; Secretaria Estadual de Saúde do Rio Grande do Norte, Natal, RN, Brasil., Mosimann AL; Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fundação Oswaldo Cruz, Curitiba, PR, Brasil., Santos GI; Secretaria Estadual de Saúde do Rio Grande do Norte, Natal, RN, Brasil., Santos CN; Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fundação Oswaldo Cruz, Curitiba, PR, Brasil., Luz K; Instituto de Medicina Tropical, Universidade Federal do Rio Grande do Norte, Natal, RN, Brasil.

Publikováno v: Memorias do Instituto Oswaldo Cruz [Mem Inst Oswaldo Cruz] 2015 Jun; Vol. 110 (4), pp. 569-72. Date of Electronic Publication: 2015 Jun 09.

High content screening of a kinase-focused library reveals compounds broadly-active against dengue viruses.

Autor: Cruz DJ; Center for Neglected Diseases Drug Discovery (CND3), Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea., Koishi AC, Taniguchi JB, Li X, Milan Bonotto R, No JH, Kim KH, Baek S, Kim HY, Windisch MP, Pamplona Mosimann AL, de Borba L, Liuzzi M, Hansen MA, Duarte dos Santos CN, Freitas-Junior LH

Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2013; Vol. 7 (2), pp. e2073. Date of Electronic Publication: 2013 Feb 21.

Genetic and biological characterization of a densovirus isolate that affects dengue virus infection.

Autor: Mosimann AL; Instituto Carlos Chagas-Fiocruz, Curitiba, PR, Brasil., Bordignon J, Mazzarotto GC, Motta MC, Hoffmann F, Santos CN

Publikováno v: Memorias do Instituto Oswaldo Cruz [Mem Inst Oswaldo Cruz] 2011 May; Vol. 106 (3), pp. 285-92.