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of 4
pro vyhledávání: '"Moshe Bentolila"'
Autor:
Agata Gitlin-Domagalska, Mattan Hurevich, Johnny N. Naoum, Moshe Bentolila, Chaim Gilon, Israel Alshanski
Publikováno v:
Organic Process Research & Development. 23:2733-2739
Mixing of polystyrene resins in solid-phase synthesis is performed by shaking or gentle agitation of the reaction vessel to avoid breaking the brittle beads. These mixing strategies result in poor diffusion to and into the beads. Using a large excess
Autor:
Dolev Zamir, Israel Alshanski, Shir Zorsky, Moshe Bentolila, Salim Joubran, Chaim Gilon, Agata Gitlin-Domagalska, Mattan Hurevich
Publikováno v:
Organic Process Research & Development. 22:1318-1322
The brittle nature of the polymer beads used in SPPS dictates mild mixing techniques with low mass transfer. We demonstrate that vigorous overhead mechanical stirring with superior mass transfer properties kept the beads intact and significantly acce
Autor:
Israel Alshanski, Mattan Hurevich, Johnny N. Naoum, Moshe Bentolila, Chaim Gilon, Agata Gitlin-Domagalska
Performing amino acids coupling reactions on solid support using fast overhead stirring is far more efficient than the common shaking mixing methods. Stirring does not harm the polystyrene beads and allows to decrease dramatically the amount of reage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6a8344ce6562243ec99afa6115088d
https://doi.org/10.26434/chemrxiv.9757511
https://doi.org/10.26434/chemrxiv.9757511
Publikováno v:
ChemEngineering; Volume 2; Issue 2; Pages: 21
We describe a hydrodynamic simulation method (HSM) that is based on hydrodynamic considerations in Batch and Semi Batch stirred reactor systems. The method combines hydrodynamic studies of the mixing procedure obtained from experiments in small and l