Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Moshe Aftalion"'
Autor:
Anita Sapoznikov, Yentl Evgy, Amir Ben-Shmuel, Arieh Schwartz, Ron Alcalay, Moshe Aftalion, Alon Ben David, Noam Erez, Reut Falach
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Ricin, an extremely potent toxin produced from the seeds of castor plant, Ricinus communis, is ribosome-inactivating protein that blocks cell-protein synthesis. It is considered a biological threat due to worldwide availability of castor bea
Externí odkaz:
https://doaj.org/article/428856100ea14947af039aa2bd97b53f
Autor:
Inbar Cohen-Gihon, Galia Zaide, Sharon Amit, Iris Zohar, Orna Schwartz, Yasmin Maor, Ofir Israeli, Gal Bilinsky, Ma’ayan Israeli, Shirley Lazar, David Gur, Moshe Aftalion, Anat Zvi, Adi Beth-Din, Erez Bar-Haim, Uri Elia, Ofer Cohen, Emanuelle Mamroud, Theodor Chitlaru
Publikováno v:
BMC Genomic Data, Vol 25, Iss 1, Pp 1-4 (2024)
Abstract Objective Burkholderia pseudomallei, the etiological cause of melioidosis, is a soil saprophyte endemic in South-East Asia, where it constitutes a public health concern of high-priority. Melioidosis cases are sporadically identified in nonen
Externí odkaz:
https://doaj.org/article/ad0550d172cd45f89daa2d0401a2cde8
Autor:
Galia Zaide, Inbar Cohen-Gihon, Ohad Shifman, Ofir Israeli, Moshe Aftalion, Sharon Maoz, Theodor Chitlaru, Raphael Ber, Anat Zvi, Ida Steinberger-Levy
Publikováno v:
BMC Genomic Data, Vol 24, Iss 1, Pp 1-4 (2023)
Abstract Objective As part of a research aiming at presenting an alternative approach for rapid determination of antimicrobial susceptibility by quantification of changes in expression levels of specific marker genes and gene sets, cultures of the vi
Externí odkaz:
https://doaj.org/article/73eeadeeac6a499ca0efc7b3f8f9bb1d
Long-Term Pulmonary Damage in Surviving Antitoxin-Treated Mice following a Lethal Ricin Intoxication
Autor:
Yoav Gal, Anita Sapoznikov, Shlomi Lazar, David Shoseyov, Moshe Aftalion, Hila Gutman, Yentl Evgy, Rellie Gez, Reinat Nevo, Reut Falach
Publikováno v:
Toxins, Vol 16, Iss 2, p 103 (2024)
Ricin, a highly potent plant-derived toxin, is considered a potential bioterrorism weapon due to its pronounced toxicity, high availability, and ease of preparation. Acute damage following pulmonary ricinosis is characterized by local cytokine storm,
Externí odkaz:
https://doaj.org/article/86b4dcb62cba4c71932b3d774e92487e
Autor:
Ma’ayan Israeli, Yaara Finkel, Yfat Yahalom-Ronen, Nir Paran, Theodor Chitlaru, Ofir Israeli, Inbar Cohen-Gihon, Moshe Aftalion, Reut Falach, Shahar Rotem, Uri Elia, Ital Nemet, Limor Kliker, Michal Mandelboim, Adi Beth-Din, Tomer Israely, Ofer Cohen, Noam Stern-Ginossar, Adi Bercovich-Kinori
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here, Israeli and Finkel et al. perform genome-wide CRISPR knockout screens to identify host factors required for the infection with SARS-CoV-2 and two additionally variants of concern, Alpha and Beta, unveiling shared and differential host pathways
Externí odkaz:
https://doaj.org/article/234527f794a946638ae72a22b7b11809
Autor:
Hagit Achdout, Einat. B. Vitner, Boaz Politi, Sharon Melamed, Yfat Yahalom-Ronen, Hadas Tamir, Noam Erez, Roy Avraham, Shay Weiss, Lilach Cherry, Erez Bar-Haim, Efi Makdasi, David Gur, Moshe Aftalion, Theodor Chitlaru, Yaron Vagima, Nir Paran, Tomer Israely
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Influenza A virus (IAV) and SARS-CoV-2 coinfection is a possible scenario during influenza season. Here, the authors show in a mouse model that IAV infection increases the risk of severe disease upon SARS-CoV-2 infection two days later. IAV vaccinati
Externí odkaz:
https://doaj.org/article/1c21769ac0654cd898e2ff49db5bd690
Autor:
Moshe Aftalion, Avital Tidhar, Yaron Vagima, David Gur, Ayelet Zauberman, Tzvi Holtzman, Arik Makovitzki, Theodor Chitlaru, Emanuelle Mamroud, Yinon Levy
Publikováno v:
Vaccines, Vol 11, Iss 3, p 581 (2023)
In a recent study, we demonstrated that vaccination with the polymeric F1 capsule antigen of the plague pathogen Yersinia pestis led to the rapid induction of a protective humoral immune response via the pivotal activation of innate-like B1b cells. C
Externí odkaz:
https://doaj.org/article/555ae72ec4e946c7902499b5bb357e6e
Autor:
Ronit Rosenfeld, Tal Noy-Porat, Adva Mechaly, Efi Makdasi, Yinon Levy, Ron Alcalay, Reut Falach, Moshe Aftalion, Eyal Epstein, David Gur, Theodor Chitlaru, Einat B. Vitner, Sharon Melamed, Boaz Politi, Ayelet Zauberman, Shirley Lazar, Adi Beth-Din, Yentl Evgy, Shmuel Yitzhaki, Shmuel C. Shapira, Tomer Israely, Ohad Mazor
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Here, using the K18-hACE2 transgenic mice model, the authors report the in vivo efficacy of a fully human neutralizing antibody against SARS-CoV-2 and show that when administered before or up to 3 days post infection, treated mice do not exhibit dise
Externí odkaz:
https://doaj.org/article/46809b3d714542f1b041f07ea3d49be0
Autor:
Inbar Cohen-Gihon, Ofir Israeli, Avital Tidhar, Anita Sapoznikov, Yentl Evgy, Dana Stein, Moshe Aftalion, David Gur, Irit Orr, Anat Zvi, Tamar Sabo, Chanoch Kronman, Reut Falach
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Severe manifestations of coronavirus disease 2019 (COVID-19) are mostly restricted to distinct groups of people who have preexisting morbidities. Most COVID-19 animal models develop a mild pathology that resolves within a relatively short period of t
Externí odkaz:
https://doaj.org/article/11b795ca9d3548e39310a72bb1c3c99f
Autor:
Ram Nechooshtan, Sharon Ehrlich, Marika Vitikainen, Arik Makovitzki, Eyal Dor, Hadar Marcus, Idan Hefetz, Shani Pitel, Marilyn Wiebe, Anne Huuskonen, Lilach Cherry, Edith Lupu, Yehuda Sapir, Tzvi Holtzman, Moshe Aftalion, David Gur, Hadas Tamir, Yfat Yahalom-Ronen, Yuval Ramot, Noam Kronfeld, David Zarling, Anne Vallerga, Ronen Tchelet, Abraham Nyska, Markku Saloheimo, Mark Emalfarb, Yakir Ophir
Publikováno v:
Vaccines, Vol 10, Iss 12, p 2119 (2022)
SARS-CoV-2 is evolving with increased transmission, host range, pathogenicity, and virulence. The original and mutant viruses escape host innate (Interferon) immunity and adaptive (Antibody) immunity, emphasizing unmet needs for high-yield, commercia
Externí odkaz:
https://doaj.org/article/8087098534aa48d98dd5ffae26105a5c