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pro vyhledávání: '"Moses Bosire"'
Autor:
William C. Hines, Irina Bazarov, Won Jae Lee, Scott W. Lowe, Alexey V. Bazarov, Moses Bosire, Paul Yaswen, Agustin Chicas, Basha Stankovich
Publikováno v:
Bazarov, AV; Lee, WJ; Bazarov, I; Bosire, M; Hines, WC; Stankovich, B; et al.(2012). The specific role of pRb in p16INK4A-mediated arrest of normal and malignant human breast cells. Cell Cycle, 11(5), 1008-1013. doi: 10.4161/cc.11.5.19492. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/77s1m9sz
RB family proteins pRb, p107 and p130 have similar structures and overlapping functions, enabling cell cycle arrest and cellular senescence. pRb, but not p107 or p130, is frequently mutated in human malignancies. In human fibroblasts acutely exposed
Autor:
Curtis Hines, Agustin Chicas, Scott W. Lowe, Irina Korobochkina, Won Jae Lee, Alexey V. Bazarov, Moses Bosire, Paul Yaswen, Rituparna Mukhopadhyay
Publikováno v:
Cancer Research. 70:3210-3210
Pocket family proteins pRb, p107 and p130 are important cell cycle regulators in mammalian cells. In addition to controlling G1 to S transition, they also participate in differentiation and senescence. While all three pocket proteins have similar str