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18F-Labeling and Radiopharmacological Evaluation of Novel Purinedione Multi-Eph Inhibitors

Autor: Mamat, C., Pretze, M., Neuber, C., Mosch, B., Steinbach, J., Pietzsch, J.

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals 58(2015), S165
21st International Symposium on Radiopharmaceutical Sciences (ISRS), 26.-31.05.2015, Columbia/Missouri, USA

Objectives: The overexpression of various Eph receptors in tumors provokes the recent interest in highly affine inhibitors as attractive leads for the development of new targeted radioligands to image cancer [1]. Selective Ephtyrosine kinase inhibito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3cd27dda124f06e9b507f9a744d0e26d
https://www.hzdr.de/publications/Publ-22085-2

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Optical imaging of COX-2: Studies on an autofluorescent 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitor

Autor: Tondera, C., Ullm, S., Laube, M., Meister, S., Neuber, C., Mosch, B., Kniess, T., Pietzsch, J.

Publikováno v: Biochemical and Biophysical Research Communications 458(2015), 40-45

This study aimed at in vivo visualization of cyclooxygenase-2 (COX-2) by optical imaging using a representative compound of a class of autofluorescent 2,3-diaryl-substituted indole-based selective COX-2 inhibitors (2,3-diaryl-indole coxibs). COX-2 wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::befbbea4ea481bff1138c8122f6b261e
https://www.hzdr.de/publications/Publ-21656-1

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Effect of [18F]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice

Autor: Schütze, C., Bergmann, R., Brüchner, K., Mosch, B., Yaromira, A., Zips, D., Hessel, F., Krause, M., Thames, H., Kotzerke, J., Steinbach, J., Baumann, M., Beuthien-Baumann, B.

Publikováno v: Radiotherapy and Oncology 111(2014), 81-87

Objective To investigate the effect of radiation dose-escalation on local control in hypoxic versus non-hypoxic hypoxic tumours defined using [18F]fluoromisonidazole ([18F]FMISO) PET. Materials and methods FaDu human squamous cell carcinomas (hSCCs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::cc09c4e9df5a2bb42274d15f6e7897ba
https://www.hzdr.de/publications/Publ-20565-1

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EphB4 negatively regulates blood vessel network formation and perfusion in human A375 melanoma xenografts

Autor: Neuber, C., Hofheinz, F., Bergmann, R., Meister, S., Jörg Steinbach, Mosch, B., Pietzsch, J.

Publikováno v: 23rd Biennial Congress of the European Association for Cancer Research (EACR), 05.-08.07.2014, München, D
European Journal of Cancer 50(2014)Suppl. 5, S62-S63
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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::050233ad1214b722083f1700571de0f3
https://www.hzdr.de/publications/Publ-20658-1

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Novel nitric oxide-releasing selective cyclooxygenase-2 inhibitors as potential radiosensitizers

Autor: Bechmann, N., Mosch, B., Knieß, T., Pietzsch, J.

Publikováno v: 23. Symposium Experimentelle Strahlentherapie und Klinische Strahlenbiologie, 27.02.-01.03.2014, Tübingen, Deutschland
23. Symposium Experimentelle Strahlentherapie und Klinische Strahlenbiologie, 27.02.-01.03.2014, Tübingen, DeutschlandBaumann M, Cordes N, Dikomey E, Krause M, Petersen C, Rodemann HP, Zips D (Hrsg.) Proceedings des 23. Symposiums Experimentelle Strahlentherapie und Klinische Strahlenbiologie, Tübingen, Rottenburg: Mayer, ISSN 1423-864X, 9-10

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4c87b12bfa9c335aa6db6ed647542e45
https://www.hzdr.de/publications/Publ-20235-2

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Metastatic potential of B16-F10 melanoma cells is enhanced by extracellular S100A4 derived from RAW264.7 macrophages

Autor: Haase-Kohn, C., Wolf, S., Herwig, N., Mosch, B., Pietzsch, J.

Publikováno v: Biochemical and Biophysical Research Communications 446(2014), 143-148

S100A4, synthesized and secreted from both tumor and stroma cells, modulates an aggressive tumor phenotype in various cancers by intracellular and extracellular interactions which are not completely understood. Because of the high content of tumor-as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::cedcb761ca7bf224c0b508007fd77a89
https://www.hzdr.de/publications/Publ-20174-1

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