Výsledky vyhledávání - "Morwenna T. Muir"

Supplementary Fig. S5 from A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen

Autor: Margaret C. Frame, Neil O. Carragher, Daniel Lietha, Alex von Kriegsheim, Amaya García-Muñoz, Ashraff Makda, Morwenna T. Muir, Adam Byron, Bryan Serrels, John C. Dawson

Quantification of YAP localization in esophageal cell lines.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aeaefc45ec2edeaa334529edbfcd1f4
https://doi.org/10.1158/1535-7163.22506288.v1

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Data from A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen

Autor: Margaret C. Frame, Neil O. Carragher, Daniel Lietha, Alex von Kriegsheim, Amaya García-Muñoz, Ashraff Makda, Morwenna T. Muir, Adam Byron, Bryan Serrels, John C. Dawson

We mutated the focal adhesion kinase (FAK) catalytic domain to inhibit binding of the chaperone Cdc37 and ATP, mimicking the actions of a FAK kinase inhibitor. We reexpressed mutant and wild-type FAK in squamous cell carcinoma (SCC) cells from which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d91c39eb635f3918725cf611b30b136
https://doi.org/10.1158/1535-7163.c.6538347

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Supplementary Table S1 from A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen

Autor: Margaret C. Frame, Neil O. Carragher, Daniel Lietha, Alex von Kriegsheim, Amaya García-Muñoz, Ashraff Makda, Morwenna T. Muir, Adam Byron, Bryan Serrels, John C. Dawson

FAK kinase-dependent dysregulation of specific FAK-binding proteins.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063d73f411d884de8a2ef1930a7ef1fe
https://doi.org/10.1158/1535-7163.22506285.v1

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Supplementary Fig. S2 from A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen

Autor: Margaret C. Frame, Neil O. Carragher, Daniel Lietha, Alex von Kriegsheim, Amaya García-Muñoz, Ashraff Makda, Morwenna T. Muir, Adam Byron, Bryan Serrels, John C. Dawson

Analysis of HDAC and FAK inhibition in SCC cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199f3d20b048fe2071c2b6c59d1e09dd
https://doi.org/10.1158/1535-7163.22506297

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Supplementary Fig. S4 from A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen

Autor: Margaret C. Frame, Neil O. Carragher, Daniel Lietha, Alex von Kriegsheim, Amaya García-Muñoz, Ashraff Makda, Morwenna T. Muir, Adam Byron, Bryan Serrels, John C. Dawson

Analysis of HDAC and FAK inhibition in A549 and Flo1 cell lines.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3f9a79c7d4c13a953af3199b6ddd03
https://doi.org/10.1158/1535-7163.22506291

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Supplementary Table S2 from A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen

Autor: Margaret C. Frame, Neil O. Carragher, Daniel Lietha, Alex von Kriegsheim, Amaya García-Muñoz, Ashraff Makda, Morwenna T. Muir, Adam Byron, Bryan Serrels, John C. Dawson

FAK combination phenotypic screen data.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed31803aa9433537431d6eb888b4290
https://doi.org/10.1158/1535-7163.22506282

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Supplementary Text from A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen

Autor: Margaret C. Frame, Neil O. Carragher, Daniel Lietha, Alex von Kriegsheim, Amaya García-Muñoz, Ashraff Makda, Morwenna T. Muir, Adam Byron, Bryan Serrels, John C. Dawson

Supplementary Materials and Methods.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d18d38261bafa3b16c2f1f48a7fb2b
https://doi.org/10.1158/1535-7163.22506279

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