Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials

Autor: Christina Reith, Colin Baigent, Lisa Blackwell, Jonathan Emberson, Enti Spata, Kelly Davies, Heather Halls, Lisa Holland, Kate Wilson, Jane Armitage, Charlie Harper, David Preiss, Alistair Roddick, Anthony Keech, John Simes, Rory Collins, Elizabeth Barnes, Jordan Fulcher, William G Herrington, Adrienne Kirby, Borislava Mihaylova, Rachel O'Connell, Pierre Amarenco, Philip Barter, D John Betteridge (deceased), Michael Blazing, Jackie Bosch, Louise Bowman, Eugene Braunwald, Christopher P Cannon, Michael Clearfield, Stuart Cobbe, Helen M Colhoun, Björn Dahlöf, Barry Davis, James de Lemos, John R Downs, Paul N Durrington, Bengt Fellström, Ian Ford, Maria Grazia Franzosi, John Fuller (deceased), Curt Furberg, Robert Glynn, David Gordon, Antonio Gotto Jr, Richard Grimm, Ajay Gupta, C Morton Hawkins, Graham A Hitman, Hallvard Holdaas (deceased), Alan Jardine, J Wouter Jukema, John JP Kastelein, Sharon Kean, John Kjekshus, Genell Knatterud (deceased), Robert H Knopp (deceased), Wolfgang Koenig, Michael Koren, Vera Krane, Martin Landray, John LaRosa, Roberto Latini, Eva Lonn, Donata Lucci, Jean MacFadyen, Peter Macfarlane, Stephen MacMahon, Aldo Maggioni, Roberto Marchioli, Ian Marschner, Lemuel Moyé, Sabina Murphy, Andrew Neil, Enrico B Nicolis, Chris Packard, Sarah Parish, Terje R Pedersen, Richard Peto, Marc Pfeffer, Neil Poulter, Sara Pressel, Jeffrey Probstfield, Mahboob Rahman, Paul M Ridker, Michele Robertson, Frank Sacks, Naveed Sattar, Roland Schmieder, Patrick W Serruys, Peter Sever, John Shaw (deceased), James Shepherd (deceased), Lara Simpson, Peter Sleight (deceased), Luigi Tavazzi, Gianni Tognoni, Andrew Tonkin, Stella Trompet, Christoph Wanner, Hans Wedel, Stephen Weis, K Michael Welch, Harvey White, John Wikstrand, Lars Wilhelmsen, Stephen Wiviott, Robin Young, Salim Yusuf, Faiez Zannad, Hiroyuki Arashi, Robert Byington, Robert Clarke, Marcus Flather, Uri Goldbourt, Shinya Goto, Jemma Hopewell, Kees Hovingh, Patricia Kearney, George Kitas, Connie Newman, Marc S Sabatine, Greg Schwartz, Liam Smeeth, Jonathan Tobert, John Varigos, Junichi Yamaguchi

Publikováno v: The Lancet, 400(10355), 832-845. Elsevier Limited

Background: Statin therapy is effective for the prevention of atherosclerotic cardiovascular disease and is widely prescribed, but there are persisting concerns that statin therapy might frequently cause muscle pain or weakness. We aimed to address t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4616cab962081ebdd901d4a6e1652a20
https://pure.amc.nl/en/publications/effect-of-statin-therapy-on-muscle-symptoms(c31d56e2-803e-4f3b-881a-6f09bfa1f0f4).html

Effect of atenolol and reserpine on selected events in the systolic hypertension in the elderly program (SHEP)*

Autor: John B. Kostis, Kenneth G. Berge, Barry R. Davis, Jeffrey L. Probstfield, C. Morton Hawkins

Publikováno v: American Journal of Hypertension. 8:1147-1153

The effect of atenolol and reserpine on incidence of strokes, coronary heart disease (CHD), cardiovascular disease (CVD), and mortality was assessed in 4736 persons aged 60 years and older with isolated systolic hypertension. Participants were random

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf9b59ec64633cb2ba832234be751bb
https://doi.org/10.1016/0895-7061(95)00363-0

Analysis of a clinical trial involving a combined mortality and adherence dependent interval censored endpoint

Autor: Lemuel A. Moyé, Barry R. Davis, C. Morton Hawkins

Publikováno v: Statistics in Medicine. 11:1705-1717

Clinical trials often involve a variety of clinical and laboratory measures that are used as endpoints and sometimes two of these measures are combined in one endpoint. When the individual components of such a combined endpoint are 'time to event' me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094875e497bff16b50357fe56cf0c6b5
https://doi.org/10.1002/sim.4780111305

Baseline characteristics in the Cholesterol and Recurrent Events (CARE) trial of secondary prevention in patients with average serum cholesterol levels

Autor: Frank M. Sacks, Jean-Lucien Rouleau, Lemuel A. Moye, Marc A. Pfeffer, J. Wayne Warnica, J. Malcolm O. Arnold, David T. Nash, Lisa E. Brown, Francois Sestier, John Rutherford, Barry R. Davis, C. Morton Hawkins, Eugene Braunwald, null The CARE Investigators

Publikováno v: The American Journal of Cardiology. 75:621-623

CARE will determine whether 5 years of cholesterol-lowering therapy reduces recurrent coronary disease events in 4,159 patients who have had an AMI. The mean total cholesterol and LDL-C levels in CARE (209 and 139 mg/dl) are similar to the average le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa0a61c743510758b901b0fc18fb914
https://doi.org/10.1016/s0002-9149(99)80631-6

Isolated Systolic Hypertension, Morbidity, and Mortality: The SHEP Experience

Autor: C. Morton, Hawkins

Publikováno v: The American journal of geriatric cardiology. 2(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::23e5256263e7de12136fed699c5fad4f
https://pubmed.ncbi.nlm.nih.gov/11416291