Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Morton, George C."'
Publikováno v:
Tetrahedron Letters. 41:3029-3033
A new solid-phase efficient route to 1,5-benzothiazepine-4-one derivatives is reported. The synthesis exploits the variety of halo-nitrobenzene derivatives available and the facile substitution of the benzamide nitrogen. A wide range of derivatives c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8394417a4b3ffb5b5f78564818296b88
https://doi.org/10.1016/s0040-4039(00)00341-5
https://doi.org/10.1016/s0040-4039(00)00341-5
Autor:
Liang Ma, Marie Pierre Cherrier, Richard Labaudiniere, Joseph J. Romano, Morton George C, Christopher Hulme, Celine Duquenne, Salvino Joseph M
Publikováno v:
Tetrahedron Letters. 41:1883-1887
This communication reveals a novel application of the so-called convertible isonitriles for the solution/solid phase generation of γ-lactam analogues. Use of tethered N-BOC aldehydes in the Ugi multi-component reaction (MCR), followed by BOC removal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::390a4ec50241504b63e2f9e34d3b8f76
https://doi.org/10.1016/s0040-4039(00)00052-6
https://doi.org/10.1016/s0040-4039(00)00052-6
Autor:
Sheng Yuh Tang, Salvino Joseph M, Richard Labaudiniere, Joseph J. Romano, Liang Ma, Morton George C, Marie Pierre Cherrier, Christopher Hulme, Steve Choi
Publikováno v:
Tetrahedron Letters. 41:1889-1893
This communication reveals novel applications of the CO2/MeOH reagent combination coupled with the UDC (Ugi/DeBOC/Cyclize) strategy. The Ugi five component condensation (5CC) affords carbamate protected amino-amides in good yield. When one of the sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22e2e5b1007c9a594dc08e2be046684f
https://doi.org/10.1016/s0040-4039(00)00053-8
https://doi.org/10.1016/s0040-4039(00)00053-8
Autor:
Christopher Hulme, Richard Labaudiniere, John Peng, Salvino Joseph M, Tim Herpin, Morton George C
Publikováno v:
Tetrahedron Letters. 39:7227-7230
This communication reveals the synthesis and application of a novel resin bound isonitrile. The resin is an example of a novel safety-catch linker which upon BOC-activation can be resin cleaved with a variety of nucleophiles. Use of this polymer supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1e4f3ae732ed86ff880e7aeb809d46f
https://doi.org/10.1016/s0040-4039(98)01593-7
https://doi.org/10.1016/s0040-4039(98)01593-7
Autor:
Tripathy, Rabindranath, McHugh, Robert J., Bacon, Edward R., Salvino, Joseph M., Morton, George C., Aimone, Lisa D., Huang, Zeck, Mathiasen, Joanne R., DiCamillo, Amy, Huffman, Mark J., McKenna, Beth A., Kopec, Karla, Lu, Lily D., Qian, Jie, Angeles, Thelma S., Connors, Thomas, Spais, Chrysanthe, Holskin, Beverly, Duzic, Emir, Schaffhauser, Hervé, Rossé, Gerard C.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 February 2012 22(3):1421-1426
Autor:
Sundar, Babu G., Bailey, Thomas R., Dunn, Derek D., Bacon, Edward R., Salvino, Joseph M., Morton, George C., Aimone, Lisa D., Zeqi, Huang, Mathiasen, Joanne R., Dicamillo, Amy, Huffman, Mark J., McKenna, Beth A., Kopec, Karla, Lu, Lily D., Brown, Rebecca, Qian, Jie, Angeles, Thelma, Connors, Thomas, Spais, Chrysanthe, Holskin, Beverly, Galinis, Deborah, Duzic, Emir, Schaffhauser, Herve, Rosse, Gerard C.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 January 2012 22(1):120-123
Autor:
Timothy F. Herpin, Morton George C
Publikováno v:
Methods in Enzymology ISBN: 9780121822729
Publisher Summary This chapter reviews the principle of directed sorting and presents two detailed examples of its application in drug discovery: (1) the synthesis of piperazine-2 carboxamide derivatives and (2) the synthesis of benzothiazepine deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3557f46dd91777931de8b57efe9f0ae
https://doi.org/10.1016/s0076-6879(03)69004-x
https://doi.org/10.1016/s0076-6879(03)69004-x
Autor:
Harikrishnan, Lalgudi S., Kamau, Muthoni G., Herpin, Timothy F., Morton, George C., Liu, Yalei, Cooper, Christopher B., Salvati, Mark E., Qiao, Jennifer X., Wang, Tammy C., Adam, Leonard P., Taylor, David S., Chen, Alice Ye A., Yin, Xiaohong, Seethala, Ramakrishna, Peterson, Tara L., Nirschl, David S., Miller, Arthur V., Weigelt, Carolyn A., Appiah, Kingsley K., O’Connell, Jonathan C., Michael Lawrence, R.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2008 18(8):2640-2644
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Publikováno v:
In Tetrahedron Letters 2000 41(17):3029-3033