Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Morten Svenson"'
Autor:
Pia Søndergaard Galle, Jakob Hjorth von Stemann, Morten Svenson, Rune Larsen, Morten Bagge Hansen, Henrik Ullum, Daniel Kring Rasmussen Guldager, Jakob Thaning Bay
Publikováno v:
Journal of Immunological Methods. 425:62-68
Purpose To establish and validate a rapid, cost-effective and accurate screening assay for the simultaneous testing of human naturally occurring anti-cytokine autoantibodies (c-aAb) targeting interleukin-1α (IL-1α), interleukin-6 (IL-6), interleuki
Autor:
Mark A. Ainsworth, Ole Østergaard Thomsen, Jørn Brynskov, Casper Steenholdt, Morten Svenson, Klaus Bendtzen
Publikováno v:
Alimentary Pharmacology & Therapeutics. 34:51-58
Aliment Pharmacol Ther 2011; 34: 51–58 Summary Background Infliximab (IFX) elicits acute severe infusion reactions in about 5% of patients with inflammatory bowel disease (IBD). Aim To investigate the role of anti-IFX antibodies (Ab) and other risk
Autor:
Bente Klarlund Pedersen, Morten Svenson, Morten Bagge Hansen, Pia Galle, Carina de Lemos Rieper
Publikováno v:
Journal of Immunological Methods. 350:46-53
Radio iodinated recombinant human IL-10 was prepared and validated for the measurement of natural human anti-IL-10 antibodies. Iodination of IL-10 was accomplished by means of the chloramine-T method. The crude tracer was purified by size chromatogra
Publikováno v:
Clinical Experimental Allergy. 36:273-282
Summary Background Human basophils and mast cells express the low-affinity immunoglobulin (Ig)G receptor FcγRIIB. It has previously been shown in artificial model systems that cross-linking of the high-affinity IgE receptor FcɛRI and FcγRIIB leads
Publikováno v:
Immunology Letters. 89:59-65
We investigated the ability of monocyte-conditioned medium (MCM), generated by monocytes cultured on plastic-immobilised immunoglobulin, to stimulate maturation of human monocyte-derived dendritic cells (DC). Earlier reports suggest that MCM is a str
Autor:
Christian Ross, Per Soelberg Sørensen, Nils Koch-Henriksen, Katja Maria Clemmesen, Klaus Bendtzen, Gunhild Lange Skovgaard, Morten Svenson
Publikováno v:
Annals of Neurology. 48:706-712
A total of 754 consecutive patients with relapsing-remitting multiple sclerosis were investigated for interferon-beta (IFNbeta) antibodies by protein-G affinity chromatography and antiviral neutralization bioassay during 24 months on 6 MIU (22 microg
Autor:
Anneline Nansen, Morten Svenson, Allan Randrup Thomsen, Ivan G. Otterness, Morten Bagge Hansen, Klaus Rieneck, Klaus Bendtzen, Marcus Diamant
Publikováno v:
Journal of Immunological Methods. 236:1-8
High-affinity IgG autoantibodies (aAb) to IL-1alpha are among the most frequently found aAb to cytokines in humans. To establish an animal model with aAb to IL-1alpha, we immunised mice with recombinant murine IL-1alpha. Unprimed and Bacille Calmette
Autor:
Peter Skinhøj, Niels Ødum, Christian N. Meyer, Morten Svenson, Klaus Bendtzen, Carsten Schade Larsen
Publikováno v:
APMIS. 108:122-130
Neutralizing cytokine antibodies are found in healthy and diseased individuals, including patients treated with recombinant cytokines. Identification of CCR-5 as co-receptor for HIV has focused interest on CC chemokines and their potential therapeuti
Autor:
Charlotte Lundsgaard, Henrik Nielsen, Morten Bagge Hansen, Christian Ross, Morten Svenson, Klaus Bendtzen
Publikováno v:
Blood. 90:2376-2380
High-avidity antibodies against interferon α (IFNα), interleukin-1α (IL-1α), and IL-6 have been demonstrated in preparations of normal human IgG, and in vivo modulation of these cytokines may therefore account for immunomodulatory and anti-inflam
Autor:
Morten Svenson, Paul Herbrink
Publikováno v:
Biotherapy. 10:87-92
Several assays have been used for detection of antibodies against cytokines. The choice of assay is greatly dependent on the intended goal, e.g. detection of naturally occurring antibodies or therapy induced antibodies. The different assays can be gr