Zobrazeno 1 - 10 of 160 pro vyhledávání: '"Morten S Olesen"'
1
Akademický článek
Quantitative proteome comparison of human hearts with those of model organisms.
Autor: Nora Linscheid, Alberto Santos, Pi Camilla Poulsen, Robert W Mills, Kirstine Calloe, Ulrike Leurs, Johan Z Ye, Christian Stolte, Morten B Thomsen, Bo H Bentzen, Pia R Lundegaard, Morten S Olesen, Lars J Jensen, Jesper V Olsen, Alicia Lundby
Publikováno v: PLoS Biology, Vol 19, Iss 4, p e3001144 (2021)
Delineating human cardiac pathologies and their basic molecular mechanisms relies on research conducted in model organisms. Yet translating findings from preclinical models to humans present a significant challenge, in part due to differences in card
Externí odkaz: https://doaj.org/article/803278d7d2314c97a5198af5d5449f9c
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2
Akademický článek
Investigating gene-microRNA networks in atrial fibrillation patients with mitral valve regurgitation.
Autor: Joana Larupa Santos, Ismael Rodríguez, Morten S Olesen, Bo Hjorth Bentzen, Nicole Schmitt
Publikováno v: PLoS ONE, Vol 15, Iss 5, p e0232719 (2020)
BACKGROUND:Atrial fibrillation (AF) is predicted to affect around 17.9 million individuals in Europe by 2060. The disease is associated with severe electrical and structural remodelling of the heart, and increased the risk of stroke and heart failure
Externí odkaz: https://doaj.org/article/ff2ac0cc5f714ac39e57605cba92eadd
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4
Akademický článek
The ABC‐Stroke Risk Score and Effects of Atrial Fibrillation Screening on Stroke Prevention: Results From the Randomized LOOP Study
Autor: Lucas Yixi Xing, Søren Zöga Diederichsen, Søren Højberg, Derk W. Krieger, Claus Graff, Ruth Frikke‐Schmidt, Pyotr G. Platonov, Morten S. Olesen, Axel Brandes, Lars Køber, Ketil Jørgen Haugan, Jesper Hastrup Svendsen
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 4 (2024)
Background The ABC‐stroke score is a risk scheme for prediction of stroke or systemic embolism (SE) in atrial fibrillation (AF). This study sought to examine whether the score could be useful in predicting stroke in AF‐naïve individuals and risk
Externí odkaz: https://doaj.org/article/16b097f7cf2045e983390ff7f9f30d21
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5
Akademický článek
Association of Common and Rare Genetic Variation in the 3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Gene and Cataract Risk
Autor: Jonas Ghouse, Gustav Ahlberg, Anne Guldhammer Skov, Henning Bundgaard, Morten S. Olesen
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 12 (2022)
Background Results from animal models and observational studies have raised concerns regarding the potential cataractogenic effects of statin treatment. We investigated whether common and rare genetic variants in HMGCR are associated with cataract ri
Externí odkaz: https://doaj.org/article/fbc5f8f384234a6cbf3e6708f485fa13
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6
Akademický článek
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease
Autor: Jonas B. Nielsen, Oren Rom, Ida Surakka, Sarah E. Graham, Wei Zhou, Tanmoy Roychowdhury, Lars G. Fritsche, Sarah A. Gagliano Taliun, Carlo Sidore, Yuhao Liu, Maiken E. Gabrielsen, Anne Heidi Skogholt, Brooke Wolford, William Overton, Ying Zhao, Jin Chen, He Zhang, Whitney E. Hornsby, Akua Acheampong, Austen Grooms, Amanda Schaefer, Gregory J. M. Zajac, Luis Villacorta, Jifeng Zhang, Ben Brumpton, Mari Løset, Vivek Rai, Pia R. Lundegaard, Morten S. Olesen, Kent D. Taylor, Nicholette D. Palmer, Yii-Der Chen, Seung H. Choi, Steven A. Lubitz, Patrick T. Ellinor, Kathleen C. Barnes, Michelle Daya, Nicholas Rafaels, Scott T. Weiss, Jessica Lasky-Su, Russell P. Tracy, Ramachandran S. Vasan, L. Adrienne Cupples, Rasika A. Mathias, Lisa R. Yanek, Lewis C. Becker, Patricia A. Peyser, Lawrence F. Bielak, Jennifer A. Smith, Stella Aslibekyan, Bertha A. Hidalgo, Donna K. Arnett, Marguerite R. Irvin, James G. Wilson, Solomon K. Musani, Adolfo Correa, Stephen S. Rich, Xiuqing Guo, Jerome I. Rotter, Barbara A. Konkle, Jill M. Johnsen, Allison E. Ashley-Koch, Marilyn J. Telen, Vivien A. Sheehan, John Blangero, Joanne E. Curran, Juan M. Peralta, Courtney Montgomery, Wayne H-H Sheu, Ren-Hua Chung, Karen Schwander, Seyed M. Nouraie, Victor R. Gordeuk, Yingze Zhang, Charles Kooperberg, Alexander P. Reiner, Rebecca D. Jackson, Eugene R. Bleecker, Deborah A. Meyers, Xingnan Li, Sayantan Das, Ketian Yu, Jonathon LeFaive, Albert Smith, Tom Blackwell, Daniel Taliun, Sebastian Zollner, Lukas Forer, Sebastian Schoenherr, Christian Fuchsberger, Anita Pandit, Matthew Zawistowski, Sachin Kheterpal, Chad M. Brummett, Pradeep Natarajan, David Schlessinger, Seunggeun Lee, Hyun Min Kang, Francesco Cucca, Oddgeir L. Holmen, Bjørn O. Åsvold, Michael Boehnke, Sekar Kathiresan, Goncalo R. Abecasis, Y. Eugene Chen, Cristen J. Willer, Kristian Hveem
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Drugs targeting cardiovascular disease (CVD) can have negative consequences for liver function. Here, the authors combine genome wide analyses on 69,479 individuals to identify loss-of-function variants with beneficial effects on CVD-related traits w
Externí odkaz: https://doaj.org/article/2eecf9230b454b46b95b45b0f20ddd2e
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7
Akademický článek
Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation
Autor: Gustav Ahlberg, Lena Refsgaard, Pia R. Lundegaard, Laura Andreasen, Mattis F. Ranthe, Nora Linscheid, Jonas B. Nielsen, Mads Melbye, Stig Haunsø, Ahmad Sajadieh, Lu Camp, Søren-Peter Olesen, Simon Rasmussen, Alicia Lundby, Patrick T. Ellinor, Anders G. Holst, Jesper H. Svendsen, Morten S. Olesen
Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Common genetic variants in structural proteins contribute to risk of atrial fibrillation (AF). Here, using whole-exome sequencing, the authors identify rare truncating variants in TTN that associate with familial and early-onset AF and show defects i
Externí odkaz: https://doaj.org/article/32b75a989a0d494f99383ba50d107a85
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8
Electrocardiographic markers of subclinical atrial fibrillation detected by implantable loop recorder:insights from the LOOP Study
Autor: Lucas Yixi Xing, Søren Zöga Diederichsen, Søren Højberg, Derk W Krieger, Claus Graff, Morten S Olesen, Jonas Bille Nielsen, Axel Brandes, Lars Køber, Ketil Jørgen Haugan, Jesper Hastrup Svendsen
Publikováno v: Xing, L Y, Diederichsen, S Z, Højberg, S, Krieger, D W, Graff, C, Olesen, M S, Nielsen, J B, Brandes, A, Køber, L, Haugan, K J & Svendsen, J H 2023, ' Electrocardiographic markers of subclinical atrial fibrillation detected by implantable loop recorder : insights from the LOOP Study ', Europace, vol. 25, no. 5, euad014 . https://doi.org/10.1093/europace/euad014
Xing, L Y, Diederichsen, S Z, Hojberg, S, Krieger, D W, Graff, C, Olesen, M S, Nielsen, J B, Brandes, A, Kober, L, Haugan, K J & Svendsen, J H 2023, ' Electrocardiographic markers of subclinical atrial fibrillation detected by implantable loop recorder : insights from the LOOP Study ', Europace, vol. 25, no. 5, euad014 . https://doi.org/10.1093/europace/euad014
Aims Insights into subclinical atrial fibrillation (AF) development are warranted to inform the strategies of screening and subsequent clinical management upon AF detection. Hence, this study sought to characterize the onset and progression of subcli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b41b407aa4fa38677c59404208f23b
https://vbn.aau.dk/ws/files/532401240/euad014.pdf
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9
Association between primary care electrocardiogram markers and Alzheimer's disease
Autor: Jonas L. Isaksen, Jonas Ghouse, Morten W. Skov, Morten S. Olesen, Anders G. Holst, Adrian Pietersen, Jonas B. Nielsen, Anja Maier, Claus Graff, Thomas A. Gerds, Ruth Frikke-Schmidt, Jørgen K. Kanters
Publikováno v: Isaksen, J L, Ghouse, J, Skov, M W, Olesen, M S, Holst, A G, Pietersen, A, Nielsen, J B, Maier, A, Graff, C, Gerds, T A, Frikke-Schmidt, R & Kanters, J K 2023, ' Association between primary care electrocardiogram markers and Alzheimer's disease ', Journal of the Neurological Sciences, vol. 447, 120581 . https://doi.org/10.1016/j.jns.2023.120581
Objective: The association between common electrocardiogram (ECG) markers and Alzheimer's disease has been scarcely investigated, and it is unknown if ECG markers can improve risk prediction. Thus, we aimed to examine the association between common E
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2edcf222fdca0be617d16d5aa784014b
https://vbn.aau.dk/da/publications/f10cc4fb-f8d3-41a0-8be2-cf2a86c00548
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10
Effects of Atrial Fibrillation Screening According to N-Terminal Pro-B-Type Natriuretic Peptide:A Secondary Analysis of the Randomized LOOP Study
Autor: Lucas Yixi Xing, Søren Zöga Diederichsen, Søren Højberg, Derk W. Krieger, Claus Graff, Ruth Frikke-Schmidt, Morten S. Olesen, Axel Brandes, Lars Køber, Ketil Jørgen Haugan, Jesper Hastrup Svendsen
Publikováno v: Xing, L Y, Diederichsen, S Z, Højberg, S, Krieger, D W, Graff, C, Frikke-Schmidt, R, Olesen, M S, Brandes, A, Køber, L, Haugan, K J & Svendsen, J H 2023, ' Effects of Atrial Fibrillation Screening According to N-Terminal Pro-B-Type Natriuretic Peptide : A Secondary Analysis of the Randomized LOOP Study ', Circulation, vol. 147, no. 24, pp. 1788-1797 . https://doi.org/10.1161/CIRCULATIONAHA.123.064361
Xing, L Y, Diederichsen, S Z, Højberg, S, Krieger, D W, Graff, C, Frikke-Schmidt, R, Olesen, M S, Brandes, A, Køber, L, Haugan, K J & Svendsen, J H 2023, ' Effects of Atrial Fibrillation Screening According to N-Terminal Pro-B-Type Natriuretic Peptide : a Secondary Analysis of the Randomized LOOP Study ', Circulation, vol. 147, no. 24, pp. 1788-1797 . https://doi.org/10.1161/circulationaha.123.064361
Xing, L Y, Diederichsen, S Z, Højberg, S, Krieger, D W, Graff, C, Frikke-Schmidt, R, Olesen, M S, Brandes, A, Køber, L, Haugan, K J & Svendsen, J H 2023, ' Effects of Systematic Atrial Fibrillation Screening According to N-Terminal Pro-B-Type Natriuretic Peptide : a Secondary Analysis of the Randomized LOOP Study ', Circulation . https://doi.org/10.1161/circulationaha.123.064361
Background:Research suggests NT-proBNP (N-terminal pro-B-type natriuretic peptide) to be a strong predictor of incident atrial fibrillation (AF) and stroke. However, its utility in AF screening remains unknown. The aim of this study was to investigat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137fda9ddba002704a278b314e21adc2
https://curis.ku.dk/ws/files/358109845/CIRCULATIONAHA.123.064361.pdf
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