Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Morten K Jensen"'
Autor:
Vibe Skov, Mark Burton, Mads Thomassen, Thomas Stauffer Larsen, Caroline H Riley, Ann Brinch Madelung, Lasse Kjær, Henrik Bondo, Inger Stamp, Mats Ehinger, Rasmus Dahl-Sørensen, Nana Brochmann, Karsten Nielsen, Jürgen Thiele, Morten K Jensen, Ole Weis Bjerrum, Torben A Kruse, Hans Carl Hasselbalch
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161570 (2016)
Recent studies have shown that a large proportion of patients classified as essential thrombocythemia (ET) actually have early primary prefibrotic myelofibrosis (prePMF), which implies an inferior prognosis as compared to patients being diagnosed wit
Externí odkaz:
https://doaj.org/article/e8a77e96cb5f4691a2d728bdace4470e
Autor:
Christian M Hagen, Frederik H Aidt, Ole Havndrup, Paula L Hedley, Morten K Jensen, Jørgen K Kanters, Tam T Pham, Henning Bundgaard, Michael Christiansen
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124540 (2015)
Hypertrophic cardiomyopathy (HCM) is a genetic cardiac disease primarily caused by mutations in genes coding for sarcomeric proteins. A molecular-genetic etiology can be established in ~60% of cases. Evolutionarily conserved mitochondrial DNA (mtDNA)
Externí odkaz:
https://doaj.org/article/347616c48d174892929bd3afcbb890c8
Autor:
Hans Carl Hasselbalch, Vibe Skov, Thomas Stauffer Larsen, Mads Thomassen, Caroline Hasselbalch Riley, Morten K Jensen, Ole Weis Bjerrum, Torben A Kruse
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85567 (2014)
Identifying a distinct gene signature for myelofibrosis may yield novel information of the genes, which are responsible for progression of essential thrombocythemia and polycythemia vera towards myelofibrosis. We aimed at identifying a simple gene si
Externí odkaz:
https://doaj.org/article/1c30885dc4a34848aa43946553046b32
Autor:
Hans Carl Hasselbalch, Mads Thomassen, Caroline Hasselbalch Riley, Lasse Kjær, Thomas Stauffer Larsen, Morten K Jensen, Ole Weis Bjerrum, Torben A Kruse, Vibe Skov
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112786 (2014)
The Philadelphia-negative chronic myeloproliferative neoplasms - essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF) (MPNs) - have recently been shown to be associated with chronic inflammation, oxidative stress and accumul
Externí odkaz:
https://doaj.org/article/5b837a83e6d64f6a91b7a96d23aa3acd
Autor:
Christian M Hagen, Frederik H Aidt, Paula L Hedley, Morten K Jensen, Ole Havndrup, Jørgen K Kanters, Johanna C Moolman-Smook, Severin O Larsen, Henning Bundgaard, Michael Christiansen
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71904 (2013)
Hypertrophic cardiomyopathy (HCM) is a genetic disorder caused by mutations in genes coding for proteins involved in sarcomere function. The disease is associated with mitochondrial dysfunction. Evolutionarily developed variation in mitochondrial DNA
Externí odkaz:
https://doaj.org/article/4388564e67bf4d619bb8318a47927675
Autor:
Anne M. Dybro, Torsten B. Rasmussen, Roni R. Nielsen, Anders L.D. Pedersen, Mads J. Andersen, Morten K. Jensen, Steen H. Poulsen
Publikováno v:
Dybro, A M, Rasmussen, T B, Nielsen, R R, Pedersen, A L D, Andersen, M J, Jensen, M K & Poulsen, S H 2023, ' Metoprolol Improves Left Ventricular Longitudinal Strain at Rest and during Exercise in Obstructive Hypertrophic Cardiomyopathy ', Journal of the American Society of Echocardiography, vol. 36, no. 2, pp. 196-204 . https://doi.org/10.1016/j.echo.2022.09.008
BACKGROUND: Patients with obstructive hypertrophic cardiomyopathy (HCM) often experience symptoms of heart failure upon exertion despite having normal left ventricular (LV) ejection fractions. Longitudinal strain (LS) may be a more sensitive marker o
Autor:
Christopher Zörner, Jannik L. Pallisgaard, Anne-Marie Schjerning, Morten K. Jensen, Jacob Tønnesen, Lise D. Vestergaard, Peter Vibe Rasmussen, Gunnar Gislason, Morten L. Hansen
Publikováno v:
Heart Rhythm. 20:S665-S666
Autor:
Paula L. Hedley, Christian M. Hagen, Joanna L. Elson, Henning Bundgaard, Julie McGaughran, Ole Havndrup, Frederik H. Aidt, Morten K. Jensen, Jørgen K. Kanters, John Atherton, Michael Christiansen
Publikováno v:
Mitochondrial DNA Part A. 31:238-244
Mitochondrial DNA (mtDNA) haplogroup (hg) H has been reported as a susceptibility factor for hypertrophic cardiomyopathy (HCM). This was established in genetic association studies, however, the SNP or SNP’s that are associated with the increased ri
Autor:
Anne M. Dybro, Torsten B. Rasmussen, Roni R. Nielsen, Mads J. Andersen, Morten K. Jensen, Steen H. Poulsen
Publikováno v:
Dybro, A M, Rasmussen, T B, Nielsen, R R, Andersen, M J, Jensen, M K & Poulsen, S H 2021, ' Randomized Trial of Metoprolol in Patients With Obstructive Hypertrophic Cardiomyopathy ', Journal of the American College of Cardiology, vol. 78, no. 25, pp. 2505-2517 . https://doi.org/10.1016/j.jacc.2021.07.065
BACKGROUND: The use of β-adrenergic receptor blocking agents in symptomatic patients with obstructive hypertrophic cardiomyopathy (HCM) rests on clinical experience and observational cohort studies.OBJECTIVES: This study aimed to investigate the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b065dc3bd8cbf1be5d9c4edadc033ed7
https://pure.au.dk/portal/da/publications/randomized-trial-of-metoprolol-in-patients-with-obstructive-hypertrophiccardiomyopathy(786f9a36-012c-476e-b8d9-72b04200abce).html
https://pure.au.dk/portal/da/publications/randomized-trial-of-metoprolol-in-patients-with-obstructive-hypertrophiccardiomyopathy(786f9a36-012c-476e-b8d9-72b04200abce).html
Autor:
Anne M. Dybro, Torsten B. Rasmussen, Roni R. Nielsen, Bertil T. Ladefoged, Mads J. Andersen, Morten K. Jensen, Steen H. Poulsen
Publikováno v:
Dybro, A M, Rasmussen, T B, Nielsen, R R, Ladefoged, B T, Andersen, M J, Jensen, M K & Poulsen, S H 2022, ' Effects of Metoprolol on Exercise Hemodynamics in Patients With Obstructive Hypertrophic Cardiomyopathy ', Journal of the American College of Cardiology, vol. 79, no. 16, pp. 1565-1575 . https://doi.org/10.1016/j.jacc.2022.02.024
Background: The relationship between exercise hemodynamics, loading conditions, and medical treatment in patients with obstructive hypertrophic cardiomyopathy (HCM) is incompletely understood. Objectives: This study aimed to investigate the effect of