Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Morten J. Buch-Pedersen"'
Autor:
Kira Ekberg, Janus Falhof, Jesper Torbøl Pedersen, Michael G. Palmgren, Morten J. Buch-Pedersen
Publikováno v:
Journal of Biological Chemistry. 290:20396-20406
The plasma membrane H+-ATPase is a P-type ATPase responsible for establishing electrochemical gradients across the plasma membrane in fungi and plants. This essential proton pump exists in two activity states: an autoinhibited basal state with a low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de7be50b30a55ebc825e77231ab8e723
https://doi.org/10.1074/jbc.m115.639385
https://doi.org/10.1074/jbc.m115.639385
Autor:
Jesper Torbøl Pedersen, Gerdi Christine Kemmer, Alex Green Wielandt, Morten J. Buch-Pedersen, Janus Falhof, Michael G. Palmgren, Anja T. Fuglsang, Anette Lund, Kira Ekberg, Thomas Günther Pomorski
Publikováno v:
Journal of Biological Chemistry. 290:16281-16291
Eukaryotic P-type plasma membrane H(+)-ATPases are primary active transport systems that are regulated at the post-translation level by cis-acting autoinhibitory domains, which can be relieved by protein kinase-mediated phosphorylation or binding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b22a6027a75bee4605e95201fead01
https://doi.org/10.1074/jbc.m114.617746
https://doi.org/10.1074/jbc.m114.617746
Autor:
John Bondo Hansen, Anne-Marie Lund Winther, Isabelle Florent, Christine Jaxel, Paul Machillot, Marc le Maire, Morten J. Buch-Pedersen, Stéphanie David-Bosne
Publikováno v:
David-Bosne, S, Florent, I, Winther, A-M L, Hansen, J B, Buch-Pedersen, M J, Machillot, P, le Maire, M & Jaxel, C 2013, ' Antimalarial screening via large-scale purification of Plasmodium falciparum Ca2+-ATPase 6 and in vitro studies ', F E B S Journal, vol. 280, no. 21, pp. 5419-29 . https://doi.org/10.1111/febs.12244
FEBS Journal
FEBS Journal, 2013, 280 (21), pp.5419-5429. ⟨10.1111/febs.12244⟩
FEBS Journal
FEBS Journal, 2013, 280 (21), pp.5419-5429. ⟨10.1111/febs.12244⟩
International audience; The most severe form of human malaria is caused by the parasite Plasmo-dium falciparum. Despite the current need, there is no effective vaccine and parasites are becoming resistant to most of the antimalarials available. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b560533e81faec610ad7197150ea9b
https://doi.org/10.1111/febs.12244
https://doi.org/10.1111/febs.12244
Autor:
Anne-Marie Lund Winther, John Bondo Hansen, Jesper V. Møller, Poul Nissen, Maike Bublitz, Morten J. Buch-Pedersen, Jesper Lykkegaard Karlsen
Publikováno v:
Nature
Winther, A-M L, Bublitz, M, Karlsen, J L, Møller, J V, Hansen, J B, Nissen, P & Buch-Pedersen, M J 2013, ' The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm ', Nature, vol. 495, no. 7440, pp. 265-269 . https://doi.org/10.1038/nature11900
Winther, A-M L, Bublitz, M, Karlsen, J L, Møller, J V, Hansen, J B, Nissen, P & Buch-Pedersen, M J 2013, ' The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm ', Nature, vol. 495, no. 7440, pp. 265-269 . https://doi.org/10.1038/nature11900
The contraction and relaxation of muscle cells is controlled by the successive rise and fall of cytosolic Ca(2+), initiated by the release of Ca(2+) from the sarcoplasmic reticulum and terminated by re-sequestration of Ca(2+) into the sarcoplasmic re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cac5ee5af6e633b3841d7b2c6052d7
https://doi.org/10.1038/nature11900
https://doi.org/10.1038/nature11900
Autor:
Michael G. Palmgren, Bjørn Panyella Pedersen, Poul Nissen, Kira Ekberg, Morten J. Buch-Pedersen, Ann K. Nielsen, Bjarke Veierskov, Danny Mollerup Sørensen
Publikováno v:
Ekberg, K, Pedersen, B P, Sørensen, D M, Nielsen, A K, Veierskov, B, Nissen, P, Palmgren, M G & Buch-Pedersen, M J 2010, ' Structural identification of cation binding pockets in the plasma membrane proton pump ', Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 50, pp. 21400-5 . https://doi.org/10.1073/pnas.1010416107
The activity of P-type plasma membrane H + -ATPases is modulated by H + and cations, with K + and Ca 2+ being of physiological relevance. Using X-ray crystallography, we have located the binding site for Rb + as a K + congener, and for Tb 3+ and Ho 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58b7589fd0f9687ea665e8455ad98bf
https://doi.org/10.1073/pnas.1010416107
https://doi.org/10.1073/pnas.1010416107
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1797(6-7):846-855
Evolution of P5 type ATPases marks the origin of eukaryotes but still they remain the least characterized pumps in the superfamily of P-type ATPases. Phylogenetic analysis of available sequences suggests that P5 ATPases should be divided into at leas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b370134dc2ad9c8b9cf7db14cc33900c
Publikováno v:
Journal of Biological Chemistry. 285:7344-7350
The activity of many P-type ATPases is found to be regulated by interacting proteins or autoinhibitory elements located in N- or C-terminal extensions. An extended C terminus of fungal and plant P-type plasma membrane H(+)-ATPases has long been recog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2c1342766ad9c081940fce49542f7f
https://doi.org/10.1074/jbc.m109.096123
https://doi.org/10.1074/jbc.m109.096123
Autor:
Kees Venema, Morten J. Buch-Pedersen, Torben S. Berner, Michael G. Palmgren, Elena L. Rudashevskaya
Publikováno v:
Journal of Biological Chemistry. 281:38285-38292
The plant plasma membrane proton pump (H(+)-ATPase) is stimulated by potassium, but it has remained unclear whether potassium is actually transported by the pump or whether it serves other roles. We now show that K(+) is bound to the proton pump at a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca67774afd672a9bf761adc67881b7f9
https://doi.org/10.1074/jbc.m604781200
https://doi.org/10.1074/jbc.m604781200
Autor:
Å. Staffan Fraysse, Morten J. Buch-Pedersen, Michael G. Palmgren, Lisbeth R. Poulsen, Bernd Wollenweber, Anders Bjørn Møller
Publikováno v:
Fraysse, Å S, Møller, A L B, Poulsen, L R, Wollenweber, B, Buch-Pedersen, M J & Palmgren, M G 2005, ' A Systematic Mutagenesis Study of Ile282 in Transmembrane Segment M4 of the Plasma Membrane H +-ATPase ', Journal of Biological Chemistry, vol. 280, no. 23, pp. 21785-21790 . https://doi.org/10.1074/jbc.M413091200
Homology models of plasma membrane H(+)-ATPase (Bukrinsky, J. T., Buch-Pedersen, M. J., Larsen, S., and Palmgren, M. G. (2001) FEBS Lett. 494, 6-10) has pointed to residues in transmembrane segment M4 as being important for proton translocation by P-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebdd25f57f921cefe6611b0f59a7d13
https://doi.org/10.1074/jbc.m413091200
https://doi.org/10.1074/jbc.m413091200
Autor:
Morten J. Buch-Pedersen, Kirsten Annette Nielsen, Charlotte Held Gotfredsen, Ralph L. Nicholson, Henriette Ammitzbøll, Jens Ø. Duus, Ole Mattsson
Publikováno v:
Physiological and Molecular Plant Pathology. 65:187-196
Sorghum ( Sorghum bicolor L.) produces 3-deoxyanthocyanidin phytoalexins. They accumulate as inclusions in cells and inhibit infection in a site-specific response. Inclusions are self-organizing 3-deoxyanthocyanidins. In aqueous solution, protons and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f9bf8b6ded6e3ba765814f54be41992
https://doi.org/10.1016/j.pmpp.2005.02.001
https://doi.org/10.1016/j.pmpp.2005.02.001