Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Morten D, Sørensen"'
Autor:
Jens, Larsen, Maja, Lambert, Henrik, Pettersson, Thomas, Vifian, Mogens, Larsen, Anna, Ollerstam, Pontus, Hegardt, Cecilia, Eskilsson, Steen, Laursen, Anders, Soehoel, Tine, Skak-Nielsen, Lene M, Hansen, Nina Ø, Knudsen, Stefan, Eirefelt, Morten D, Sørensen, Tatiana G, Stilou, Simon F, Nielsen
Publikováno v:
Journal of medicinal chemistry. 63(23)
We describe the design of a novel PDE4 scaffold and the exploration of the dual-soft concept to reduce systemic side effects via rapid elimination: introducing ester functionalities that can be inactivated in blood as well as by the liver (dual-soft)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91d778dd5cf2a7a2234d7f9358d53149
https://pubmed.ncbi.nlm.nih.gov/33054196
https://pubmed.ncbi.nlm.nih.gov/33054196
Publikováno v:
Journal of Chemical Information & Modeling; Mar2009, Vol. 49 Issue 3, p658-669, 12p