Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Morten C. Eike"'
Autor:
Tommi Välikangas, Niina Lietzén, Maria K. Jaakkola, Lars Krogvold, Morten C. Eike, Henna Kallionpää, Soile Tuomela, Clayton Mathews, Ivan C. Gerling, Sami Oikarinen, Heikki Hyöty, Knut Dahl-Jorgensen, Laura L. Elo, Riitta Lahesmaa
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Although type 1 diabetes (T1D) is primarily a disease of the pancreatic beta-cells, understanding of the disease-associated alterations in the whole pancreas could be important for the improved treatment or the prevention of the disease. We have char
Externí odkaz:
https://doaj.org/article/98e96d37ec7c4f9d9bac17ff104c747d
Publikováno v:
Genes & Immunity. 10:56-67
The major histocompatibility complex (MHC) is known to harbour genetic risk factors for type 1 diabetes (T1D) additional to the class II determinants HLA-DRB1, -DQA1 and -DQB1, but strong linkage disequilibrium (LD) has made efforts to establish thei
Publikováno v:
Cellular and Molecular Life Sciences CMLS. 62:3080-3091
To investigate whether silencing of a T-DNA-carried nptII gene in five single-copy transgenic Arabidopsis lines might be due to position effects, genomic DNA flanking the insertions was analysed for gene density, GC content, presence of short repeats
Autor:
Oskar Skog, Sami Oikarinen, Noel G. Morgan, Trond Buanes, Lars Krogvold, Dag E. Undlien, Morten C. Eike, Jutta E. Laiho, Mahesh Anagandula, Maarit Oikarinen, Knut Dahl-Jørgensen, Olle Korsgren, Pia Leete, Gun Frisk, Kristian F. Hanssen, Johnny Ludvigsson, Bjørn Edwin, Heikki Hyöty, Sarah J. Richardson
Publikováno v:
Diabetes. 64(5)
The Diabetes Virus Detection study (DiViD) is the first to examine fresh pancreatic tissue at the diagnosis of type 1 diabetes for the presence of viruses. Minimal pancreatic tail resection was performed 3–9 weeks after onset of type 1 diabetes in
Autor:
Lars Alfredsson, Morten C. Eike, Darren Plant, Nina A. Daha, Benedicte A. Lie, Tore K Kvien, Maria Seddighzadeh, Leonid Padyukov, Beate Skinningsrud, Marcus Ronninger, René E. M. Toes, Jane Worthington
Publikováno v:
PLoS ONE
PLoS ONE, 7(3)
PLoS ONE, Vol 7, Iss 3, p e32861 (2012)
PLoS ONE, 7(3)
PLoS ONE, Vol 7, Iss 3, p e32861 (2012)
HLA-DRB1 shared epitope (SE) alleles are the strongest genetic determinants for autoantibody positive rheumatoid arthritis (RA). One of the key regulators in expression of HLA class II receptors is MHC class II transactivator (CIITA). A variant of th
Publikováno v:
BMC Geriatrics, Vol 11, Iss 1, p 16 (2011)
BMC Geriatrics
BMC Geriatrics
Background Studies have shown that residents in nursing homes often are exposed to inappropriate medication. Particular concern has been raised about the consumption of psychoactive drugs, which are commonly prescribed for nursing home residents suff
Publikováno v:
Norsk Epidemiologi, Vol 20, Iss 1 (2011)
Objectives: Since the early 1990s there has been an increasing awareness of social and ethnic inequity in health and for the last few years there has also been an increasing focus on disparities in the quality of health services to ethnic minority gr
Publikováno v:
Diabetes, obesitymetabolism. 11
Aim The aim of this study was to test the microsatellites in the Type 1 Diabetes Genetics Consortium major histocompatibility complex (MHC) data set for association with type 1 diabetes (T1D) independent of the HLA-DRB1, -DQA1 and -DQB1 genes. Method
Autor:
Kjersti S. Rønningen, Morten C. Eike, Marita Olsson, Knut Dahl-Jørgensen, Benedicte A. Lie, Geir Joner, Erik Thorsby, Dag E. Undlien
Publikováno v:
Genes and immunity. 10(2)
The main genetic predisposition to type 1 diabetes (T1D) is known to be conferred by the HLA-DRB1, -DQA1 and -DQB1 genes in the major histocompatibility complex (MHC). Other genetic factors within this complex are known to contribute, but their ident
Autor:
Kjetill S. Jakobsen, Trine J. Meza, Magne Skårn, Reidunn B. Aalen, Morten C. Eike, Inderjit S. Mercy
Publikováno v:
Transgenic research. 15(4)
Transgene silencing in plants is most often dependent on homologous sequences, e.g. tandemly repeated T-DNAs. We have identified an Arabidopsis line (ex2–4 line 4) displaying silencing of the T-DNA-born nptII gene. This line contains a truncated co