In situ high-resolution structure of the baseplate antenna complex in Chlorobaculum tepidum

Autor: Jakob Toudahl Nielsen, Natalia V. Kulminskaya, Morten Bjerring, Juha M. Linnanto, Margus Rätsep, Marie Østergaard Pedersen, Petar H. Lambrev, Márta Dorogi, Győző Garab, Karen Thomsen, Caroline Jegerschöld, Niels-Ulrik Frigaard, Martin Lindahl, Niels Chr. Nielsen

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)

The chlorosome of the photosynthetic bacterium C. tepidumharvests light and transfers the energy to the photosynthetic reaction centre. Here the authors determine the structure of the baseplate, a scaffolding super-structure, to show that the basepla

Externí odkaz: https://doaj.org/article/11b81cc89417464ab8b2b9a3f42d0f15

Critical Influence of Cosolutes and Surfaces on the Assembly of Serpin-Derived Amyloid Fibrils

Autor: Dennis Wilkens Juhl, Morten Bjerring, Joachim Mathiesen, Jan J. Enghild, Daniel E. Otzen, Niels Chr. Nielsen, Michael W. Risør

Publikováno v: Risør, M W, Juhl, D W, Bjerring, M, Mathiesen, J, Enghild, J J, Nielsen, N C & Otzen, D E 2017, ' Critical Influence of Cosolutes and Surfaces on the Assembly of Serpin-Derived Amyloid Fibrils ', Biophysical Journal, vol. 113, no. 3, pp. 580-596 . https://doi.org/10.1016/j.bpj.2017.06.030

Many proteins and peptides self-associate into highly ordered and structurally similar amyloid cross- β aggregates. This fibrillation is critically dependent on properties of the protein and the surrounding environment that alter kinetic and thermod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3216de4ec696d39288937fc725ae600d
https://doi.org/10.1016/j.bpj.2017.06.030

A solid state NMR study of layered double hydroxides intercalated with para-amino salicylate, a tuberculosis drug

Autor: Morten Bjerring, Ulla Gro Nielsen, Nicholai Daugaard Jensen

Publikováno v: Jensen, N D, Bjerring, M & Nielsen, U G 2016, ' A solid state NMR study of layered double hydroxides intercalated with para-amino salicylate, a tuberculosis drug ', Solid State Nuclear Magnetic Resonance, vol. 78, pp. 9-15 . https://doi.org/10.1016/j.ssnmr.2016.06.001
Jensen, N D, Bjerring, M & Nielsen, U G 2016, ' A solid state NMR study of Layered double hydroxides intercalated with para-amino salicylate, a tuberculosis drug ', Solid State Nuclear Magnetic Resonance, vol. 78, pp. 9-15 . https://doi.org/10.1016/j.ssnmr.2016.06.001

Para-amino salicylate (PAS), a tuberculosis drug, was intercalated in three different layered double hydroxides (MgAl, ZnAl, and CaAl-LDH) and the samples were studied by multi-nuclear ((1)H, (13)C, and (27)Al) solid state NMR (SSNMR) spectroscopy in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d75c9a388f4cf1420d0da418fabe7c1
https://doi.org/10.1016/j.ssnmr.2016.06.001

Structure and Function of the Bacterial Protein Toxin Phenomycin

Autor: Kristian M. Jacobsen, Esben B. Svenningsen, Rasmus K. Flygaard, Thomas B. Poulsen, Lasse Jenner, Ditlev E. Brodersen, Thomas Tørring, Jakob Nielsen, Camilla K. Larsen, Bente Krogh Hansen, Lan B. Van, Lene N. Nejsum, Frans A. A. Mulder, Morten Bjerring

Publikováno v: Structure
Structure, 2020, 28 (5), pp.528-539. ⟨10.1016/j.str.2020.03.003⟩
Hansen, B K, Larsen, C K, Nielsen, J T, Svenningsen, E B, Van, L B, Jacobsen, K M, Bjerring, M, Flygaard, R K, Jenner, L B, Nejsum, L N, Brodersen, D E, Mulder, F A A, Tørring, T & Poulsen, T B 2020, ' Structure and Function of the Bacterial Protein Toxin Phenomycin ', Structure, vol. 28, no. 5, pp. 528-539.e9 . https://doi.org/10.1016/j.str.2020.03.003

SummaryPhenomycin is a bacterial mini-protein of 89 amino acids discovered more than 50 years ago with toxicity in the nanomolar regime towards mammalian cells. The protein inhibits the function of the eukaryotic ribosome in cell free systems and app

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b66d48cdf32bd64ee96a20bcfec3b3a
https://doi.org/10.1016/j.str.2020.03.003

Improving spectral resolution in biological solid-state NMR using phase-alternated rCW heteronuclear decoupling

Autor: Morten Bjerring, Niels Chr. Nielsen, Asif Equbal, Perunthiruthy K. Madhu

Publikováno v: Equbal, A, Bjerring, M, Madhu, P K & Nielsen, N C 2015, ' Improving spectral resolution in biological solid-state NMR using phase-alternated rCW heteronuclear decoupling ', Chemical Physics Letters, vol. 635, pp. 339-344 . https://doi.org/10.1016/j.cplett.2015.07.008

The successful application of solid-state NMR spectroscopy for structural study of biological macromolecules requires high spectral resolution. In presence of abundant H 1 spins, the resolution of the prevailing C 13 or N 15 chemical shift encoding e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523da39940180643954c95a6ed1a2772
https://doi.org/10.1016/j.cplett.2015.07.008