Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

RNA-binding properties orchestrate TDP-43 homeostasis through condensate formation in vivo.

Autor: Scherer NM; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Maurel C; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Graus MS; The David Richmond Laboratory for Cardio-Vascular Development: gene regulation and editing, Centenary Institute, The University of Sydney, School of Medical Sciences, Sydney, NSW 2006, Australia.; Genome Imaging Centre, Centenary Institute, The University of Sydney, Sydney, NSW 2006, Australia., McAlary L; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia., Richter G; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Radford RAW; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Hogan A; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Don EK; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Lee A; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Yerbury J; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia., Francois M; The David Richmond Laboratory for Cardio-Vascular Development: gene regulation and editing, Centenary Institute, The University of Sydney, School of Medical Sciences, Sydney, NSW 2006, Australia.; Genome Imaging Centre, Centenary Institute, The University of Sydney, Sydney, NSW 2006, Australia., Chung RS; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia., Morsch M; Faculty of Medicine, Health & Human Sciences, Macquarie Medical School, MND Research Centre, Macquarie University, Sydney, NSW 2109, Australia.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 May 22; Vol. 52 (9), pp. 5301-5319.

Cyclin F, Neurodegeneration, and the Pathogenesis of ALS/FTD.

Autor: Rayner SL; Macquarie Medical School, Macquarie University, Sydney, Australia., Hogan A; Macquarie Medical School, Macquarie University, Sydney, Australia., Davidson JM; Macquarie Medical School, Macquarie University, Sydney, Australia., Cheng F; Macquarie Medical School, Macquarie University, Sydney, Australia., Luu L; Macquarie Medical School, Macquarie University, Sydney, Australia., Morsch M; Macquarie Medical School, Macquarie University, Sydney, Australia., Blair I; Macquarie Medical School, Macquarie University, Sydney, Australia., Chung R; Macquarie Medical School, Macquarie University, Sydney, Australia., Lee A; Macquarie Medical School, Macquarie University, Sydney, Australia.

Publikováno v: The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry [Neuroscientist] 2024 Apr; Vol. 30 (2), pp. 214-228. Date of Electronic Publication: 2022 Sep 05.

A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration.

Autor: San Gil R; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Pascovici D; Insight Stats, Croydon Park, NSW, Australia.; Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, North Ryde Sydney, NSW, Australia., Venturato J; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Brown-Wright H; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Mehta P; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.; Motor Neuron Disease Research Centre, Macquarie Medical School, Macquarie University, Sydney, NSW, Australia., Madrid San Martin L; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Wu J; Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, North Ryde Sydney, NSW, Australia., Luan W; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Chui YK; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Bademosi AT; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Swaminathan S; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Naidoo S; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; Centre for Brain Research, University of Auckland, Auckland, New Zealand., Berning BA; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Wright AL; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Keating SS; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Curtis MA; Centre for Brain Research, University of Auckland, Auckland, New Zealand.; Department of Anatomy and Medical Imaging, University of Auckland, Auckland, New Zealand., Faull RLM; Centre for Brain Research, University of Auckland, Auckland, New Zealand.; Department of Anatomy and Medical Imaging, University of Auckland, Auckland, New Zealand., Lee JD; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, St Lucia, Brisbane, QLD, Australia., Ngo ST; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, Australia., Lee A; Motor Neuron Disease Research Centre, Macquarie Medical School, Macquarie University, Sydney, NSW, Australia., Morsch M; Motor Neuron Disease Research Centre, Macquarie Medical School, Macquarie University, Sydney, NSW, Australia., Chung RS; Motor Neuron Disease Research Centre, Macquarie Medical School, Macquarie University, Sydney, NSW, Australia., Scotter E; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; Centre for Brain Research, University of Auckland, Auckland, New Zealand., Lisowski L; Vector and Genome Engineering Facility, Children's Medical Research Institute, Westmead, NSW, Australia.; Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine - National Research Institute, Warsaw, Poland.; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia., Mirzaei M; Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, North Ryde Sydney, NSW, Australia., Walker AK; Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia. adam.walker@uq.edu.au.

Publikováno v: Nature communications [Nat Commun] 2024 Feb 19; Vol. 15 (1), pp. 1508. Date of Electronic Publication: 2024 Feb 19.

Identification of phosphorylated tau protein interactors in progressive supranuclear palsy (PSP) reveals networks involved in protein degradation, stress response, cytoskeletal dynamics, metabolic processes, and neurotransmission.

Autor: Radford RAW; Centre for Motor Neuron Disease Research, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, North Ryde, Australia., Rayner SL; Centre for Motor Neuron Disease Research, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, North Ryde, Australia., Szwaja P; Centre for Motor Neuron Disease Research, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, North Ryde, Australia., Morsch M; Centre for Motor Neuron Disease Research, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, North Ryde, Australia., Cheng F; Centre for Motor Neuron Disease Research, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, North Ryde, Australia., Zhu T; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Queensland, Brisbane, Australia., Widagdo J; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Queensland, Brisbane, Australia., Anggono V; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Queensland, Brisbane, Australia., Pountney DL; School of Pharmacy and Medical Sciences, Griffith University, Queensland, Gold Coast, Australia., Chung R; Centre for Motor Neuron Disease Research, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, North Ryde, Australia., Lee A; Centre for Motor Neuron Disease Research, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, North Ryde, Australia.

Publikováno v: Journal of neurochemistry [J Neurochem] 2023 May; Vol. 165 (4), pp. 563-586. Date of Electronic Publication: 2023 Mar 21.