Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Morrison, Zheng"'
Autor:
Zhao, Juan, Dang, Xindi, Zhang, Peixin, Nguyen, Lam Nhat, Cao, Dechao, Wang, Lin, Wu, Xiaoyuan, Morrison, Zheng D., Zhang, Ying, Jia, Zhansheng, Xie, Qian, Wang, Ling, Ning, Shunbin, El Gazzar, Mohamed, Moorman, Jonathan P., Yao, Zhi Q.
Publikováno v:
ETSU Faculty Works.
T cells have a crucial role in viral clearance and vaccine response; however, the mechanisms regulating their responses to viral infections or vaccinations remain elusive. In this study, we investigated T-cell homeostasis, apoptosis, DNA damage, and
Autor:
Wang, Ling, Cao, Dechao, Zhao, Juan, Nguyen, Lam Nhat, Dang, Xindi, Ji, Yingjie, Wu, Xiao Y., Morrison, Zheng D., Xie, Qian, El Gazzar, Mohamed, Ning, Shunbin, Moorman, Jonathon P., Yao, Zhi Q.
Publikováno v:
ETSU Faculty Works.
Virus-infected cells can regulate non-permissive bystander cells, but the precise mechanisms remain incompletely understood. Here we report that this process can be mediated by transfer of viral RNA-loaded exosomes shed from infected cells to myeloid
Autor:
Cao, Dechao, Zhao, Juan, Nguyen, Lan N., Nguyen, Lam N. T., Khanal, Sushant, Dang, Xindi, Schank, Madison, Thakuri, Bal K. Chand, Wu, Xiao Y., Morrison, Zheng D., El Gazzar, Mohamed, Zou, Yue, Ning, Shunbin, Wang, Ling, Moorman, Jonathan P., Yao, Zhi Q.
Publikováno v:
ETSU Faculty Works.
T cells in chronic viral infections are featured by premature aging with accelerated telomere erosion, but the mechanisms underlying telomere attrition remain unclear. Here, we employed human CD4 T cells treated with KML001 (a telomere-targeting drug
Autor:
Wang, Ling, Zhao, Juan, Ren, Junping P., Wu, Xiao Y., Morrison, Zheng D., El Gazzar, Mohamed A., Ning, Shunbin, Moorman, Jonathan P., Yao, Zhi Q.
Publikováno v:
ETSU Faculty Works.
Objective: Regulatory T cells (Tregs) contribute to HIV-1 disease progression by impairing antiviral immunity; however, the precise mechanisms responsible for the development of Tregs in the setting of HIV-1 infection are incompletely understood. Des
Autor:
Ren, Jun P., Zhao, Juan, Dai, Jun, Griffin, Jeddidiah W. D., Wang, Ling, Wu, Xiao Y., Morrison, Zheng D., Li, Guang Y., El Gazzar, Mohamed, Ning, Shun B., Moorman, Jonathan P.
Publikováno v:
ETSU Faculty Works.
T cells play a pivotal role in controlling viral infection; however, the precise mechanisms responsible for regulating T‐cell differentiation and function during infections are incompletely understood. In this study, we demonstrated an expansion of
Externí odkaz:
https://dc.etsu.edu/etsu-works/6536
Autor:
Nguyen, Lam Nhat, Zhao, Juan, Cao, Dechao, Dang, Xindi, Wang, Ling, Lian, Jianqi, Zhang, Ying, Jia, Zhansheng, Wu, Xiao Y., Morrison, Zheng, Xie, Qian, Ji, Yingjie, Zhang, Zheng, El Gazzar, Mohammed, Ning, Shunbin, Moorman, Jonathan P., Yao, Zhi Q.
Publikováno v:
ETSU Faculty Works.
T cells play a crucial role in viral clearance and vaccine responses; however, the mechanisms that regulate their homeostasis during viral infections remain unclear. In this study, we investigated the machineries of T-cell homeostasis and telomeric D
Autor:
Ji, Yingjie, Dang, Xindi, Nguyen, Lam Ngoc Thao, Nguyen, Lam Nhat, Zhao, Jaun, Cao, Dechao, Khanal, Sushant, Schank, Madison, Wu, Xiao Y., Morrison, Zheng D., Zou, Yue, El Gazzar, Mohamed, Ning, Shunbin, Wang, Ling, Moorman, Jonathan P., Yao, Zhi Q.
Publikováno v:
ETSU Faculty Works.
Background: T cells play a key role in controlling viral infections; however, the underlying mechanisms regulating their functions during human viral infections remain incompletely understood. Here, we used CD4 T cells derived from individuals with c
Autor:
Zhao, Juan, Schank, Madison, Wang, Ling, Li, Zhengke, Nguyen, Lam N., Dang, Xindi, Cao, Dechao, Khanal, Sushant, Thakuri, Bal K., Ogbu, Stella C., Lu, Zeyuan, Wu, Xiao Y., Morrison, Zheng D., El Gazzar, Mohamed, Liu, Ying, Zhang, Jinyu, Ning, Shunbin
Publikováno v:
ETSU Faculty Works.
The hallmark of HIV/AIDS is a gradual depletion of CD4 T cells. Despite effective control by antiretroviral therapy (ART), a significant subgroup of people living with HIV (PLHIV) fails to achieve complete immune reconstitution, deemed as immune non-
Autor:
Nguyen, Lam N. T., Nguyen, Lam N., Zhao, Juan, Schank, Madison, Dang, Xindi, Cao, Dechao, Khanal, Sushant, Chand Thakuri, Bal K., Lu, Zeyuan, Zhang, Jinyu, Li, Zhengke, Morrison, Zheng D., Wu, Xiao Y., El Gazzar, Mohamed, Ning, Shunbin, Wang, Ling, Moorman, Jonathan P., Yao, Zhi Q.
Publikováno v:
ETSU Faculty Works.
T cells are critical for the control of viral infections and T cell responses are regulated by a dynamic network of non-coding RNAs, including microRNAs (miR) and long non-coding RNAs (lncRNA). Here we show that an activation-induced decline of lncRN
Autor:
Cao, Dechao, Khanal, Sushant, Wang, Ling, Li, Zhengke, Zhao, Juan, Nguyen, Lam N., Dang, Xindi, Schank, Madison, Thakuri, Bal K. C., Zhang, Jinyu, Lu, Zeyuan, Wu, Xiao Y., Morrison, Zheng D., El Gazzar, Mohamed, Ning, Shunbin, Moorman, Jonathan P., Yao, Zhi Q.
Publikováno v:
ETSU Faculty Works.
CD4 T cell death or survival following initial HIV infection is crucial for the development of viral reservoirs and latent infection, making its evaluation critical in devising strategies for HIV cure. Here we infected primary CD4 T cells with a wild