Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens.

Autor: Morrison, Huntly M.¹ (AUTHOR), Craft, Julia² (AUTHOR), Rivera-Lugo, Rafael¹ (AUTHOR), Johnson, Jeffery R.³ (AUTHOR), Golovkine, Guillaume R.¹ (AUTHOR), Bell, Samantha L.⁴ (AUTHOR), Dodd, Claire E.¹ (AUTHOR), Van Dis, Erik¹ (AUTHOR), Beatty, Wandy L.⁵ (AUTHOR), Margolis, Shally R.¹ (AUTHOR), Repasy, Teresa¹ (AUTHOR), Shaker, Isaac² (AUTHOR), Lee, Angus Y.⁶ (AUTHOR), Vance, Russell E.^1,7 (AUTHOR), Stanley, Sarah A.^1,8 (AUTHOR), Watson, Robert O.⁴ (AUTHOR), Krogan, Nevan J.³ (AUTHOR), Portnoy, Daniel A.¹ (AUTHOR), Penn, Bennett H.² (AUTHOR) bhpenn@ucdavis.edu, Cox, Jeffery S.¹ (AUTHOR) bhpenn@ucdavis.edu

Publikováno v: PLoS Pathogens. 6/23/2023, Vol. 18 Issue 6, p1-25. 25p.

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens

Autor: Morrison, Huntly, Craft, Julia, Rivera-Lugo, Rafael, Johnson, Jeffery, Golovkine, Guillaume, Bell, Samantha, Dodd, Claire, Van Dis, Erik, Beatty, Wandy, Margolis, Shally, Repasy, Teresa, Shaker, Isaac, Lee, Angus, Vance, Russell, Stanley, Sarah, Watson, Robert, Krogan, Nevan, Portnoy, Daniel, Penn, Bennett, Cox, Jeffery

Publikováno v: PLoS Pathogens, vol 19, iss 6

Macrophages employ an array of pattern recognition receptors to detect and eliminate intracellular pathogens that access the cytosol. The cytosolic carbohydrate sensors Galectin-3, -8, and -9 (Gal-3, Gal-8, and Gal-9) recognize damaged pathogen-conta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::50b07cd9be6d043ab09be50dcb941144
https://escholarship.org/uc/item/476653cc

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IFN-γ-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1α.

Autor: Van Dis, Erik, Fox, Douglas M., Morrison, Huntly M., Fines, Daniel M., Babirye, Janet Peace, McCann, Lily H., Rawal, Sagar, Cox, Jeffery S., Stanley, Sarah A.

Publikováno v: PLoS Pathogens; 7/25/2022, Vol. 18 Issue 7, p1-23, 23p

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