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pro vyhledávání: '"Morrie Lam"'
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
N,N-dimethyl-3β-hydroxycholenamide (DMHCA) is an experimental pharmaceutical and a steroidal liver X receptor (LXR) agonist, which does not induce undesired hepatic lipogenesis. Herein, DMHCA was evaluated for its retinal effects on normal C57BL/6J
Externí odkaz:
https://doaj.org/article/d441b06c1871469d803240d713e79c47
Publikováno v:
Molecular Pharmacology. 93:101-108
Cytochrome P450 27A1 (CYP27A1) is a ubiquitous enzyme that hydroxylates cholesterol and other sterols. Complete CYP27A1 deficiency owing to genetic mutations is detrimental to human health, whereas 50% of activity retention is not and does not affect
Autor:
Aicha Saadane, Natalia Mast, Morrie Lam, Nicole El-Darzi, Irina A. Pikuleva, Artem A. Astafev
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology, Vol 9 (2018)
N,N-dimethyl-3β-hydroxycholenamide (DMHCA) is an experimental pharmaceutical and a steroidal liver X receptor (LXR) agonist, which does not induce undesired hepatic lipogenesis. Herein, DMHCA was evaluated for its retinal effects on normal C57BL/6J
Autor:
Erin Maxfield, Natalia Mast, Irina A. Pikuleva, Alexey M. Petrov, Jean Moon, Young Li, Morrie Lam
Publikováno v:
SSRN Electronic Journal.
Efavirenz, the FDA-approved anti-retroviral medication, will soon be evaluated in the clinical trial in patients with mild cognitive impairment or early dementia due to Alzheimer's disease. Efavirenz will be assessed for activation of cytochrome P450