Cathelicidin-inspired antimicrobial peptides as novel antifungal compounds

Autor: van Eijk, Martin, Boerefijn, Stephanie, Rosa, Marisela, Morren, Marnix J H, van der Ent, Cornelis K, Kraak, Bart, Dijksterhuis, Jan, Valdes Barrera, I.D., Haagsman, Henk P, de Cock, Hans

Fungal infections in humans are increasing worldwide and are currently mostly treated with a relative limited set of antifungals. Resistance to antifungals is increasing, for example, in Aspergillus fumigatus and Candida auris, and expected to increa

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https://dspace.library.uu.nl/handle/1874/408091

Cathelicidin-inspired antimicrobial peptides as novel antifungal compounds.

Autor: van Eijk M; Division of Molecular Host Defence, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Boerefijn S; Division of Molecular Host Defence, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.; Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands., Cen L; Molecular Microbiology, Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands., Rosa M; Division of Molecular Host Defence, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Morren MJH; Division of Molecular Host Defence, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., van der Ent CK; Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands., Kraak B; Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands., Dijksterhuis J; Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands., Valdes ID; Molecular Microbiology, Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands., Haagsman HP; Division of Molecular Host Defence, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., de Cock H; Molecular Microbiology, Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Medical mycology [Med Mycol] 2020 Nov 10; Vol. 58 (8), pp. 1073-1084.