Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Morphogen activity"'
Autor:
Cécile Giordano, Thomas Tognacci, Laurence Lavenant-Staccini, Tamás Matusek, Tanvi Gore, Catherine Rabouille, Pascal P. Thérond, Gisela D'Angelo
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2021, 148 (5), ⟨10.1242/dev.191791⟩
Development (Cambridge, England), 2021, 148 (5), ⟨10.1242/dev.191791⟩
Development (Cambridge), 148(5). Company of Biologists Ltd
DEVELOPMENT, 148(5):191791. COMPANY OF BIOLOGISTS LTD
Development (Cambridge, England), Company of Biologists, 2021, 148 (5), ⟨10.1242/dev.191791⟩
Development (Cambridge, England), 2021, 148 (5), ⟨10.1242/dev.191791⟩
Development (Cambridge), 148(5). Company of Biologists Ltd
DEVELOPMENT, 148(5):191791. COMPANY OF BIOLOGISTS LTD
The Hedgehog (Hh) morphogen gradient is required for patterning during metazoan development, yet the mechanisms involved in Hh apical and basolateral release and how this influences short- and long-range target induction are poorly understood. We fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3881037a4a6e970d84036bd923038e3
https://hal.archives-ouvertes.fr/hal-03414597
https://hal.archives-ouvertes.fr/hal-03414597
Autor:
David M. Gardiner, Susan V. Bryant
Publikováno v:
The International Journal of Developmental Biology. 62:363-368
The explosive growth of information from genetics and genomics has led to an appreciation of the conservation of gene regulatory networks between organisms, and between development and regeneration. With ever increasing knowledge, it will be possible
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2019)
Frontiers in Neuroscience
Frontiers in Neuroscience
Traumatic brain injury (TBI) often leads to severe neurobehavioral impairment, but the underlying molecular mechanism remains to be elucidated. Here, we collected the sera from 23 patients (aged from 19 to 81 years old, third day after TBI as TBI-thi
Publikováno v:
Development
During embryonic development, the telecephalon undergoes extensive growth and cleaves into right and left cerebral hemispheres. Although molecular signals have been implicated in this process and linked to congenital abnormalities, few studies have e
Publikováno v:
Methods in Molecular Biology ISBN: 9781493989034
Spatiotemporal patterns of morphogen activity drive differential gene expression with a high degree of precision within a developing embryo and reproducibly between embryos. Understanding the formation and function of a morphogen gradient during deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0254770695cad6b046f4b20e66da6046
https://doi.org/10.1007/978-1-4939-8904-1_10
https://doi.org/10.1007/978-1-4939-8904-1_10
Autor:
Eric D. Siggia, Fred Etoc, Jakob J. Metzger, Iain Martyn, Thomas L. Carroll, Anna Yoney, Ali H Brivanlou, Shu Li, Albert Ruzo, Christoph Kirst
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Self-organization of discrete fates in human gastruloids is mediated by a hierarchy of signaling pathways. How these pathways are integrated in time, and whether cells maintain a memory of their signaling history remains obscure. Here, we dissect the
Publikováno v:
Methods in Molecular Biology ISBN: 9781493987719
In the zebrafish embryo, cells of the early blastula animal pole are all equivalent and are fully pluripotent until the midblastula transition that occurs at the tenth cell cycle (512 to 1K cells). This naive territory of the embryo is therefore perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5be76efea8a64597542edf7e15eced7
https://doi.org/10.1007/978-1-4939-8772-6_7
https://doi.org/10.1007/978-1-4939-8772-6_7
Autor:
Will W. Minuth
Publikováno v:
Molecular and Cellular Pediatrics
Numerous investigations are dealing with anlage of the mammalian kidney and primary development of nephrons. However, only few information is available about the last steps in kidney development leading at birth to a downregulation of morphogen activ
During embryogenesis, signaling molecules initiate cell diversification, sometimes via stochastic processes, other times via the formation of long range gradients of activity which pattern entire fields of cells. Such mechanisms are not insensitive t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc91489635016d42f17817e674a39fd
https://doi.org/10.1101/138354
https://doi.org/10.1101/138354
Autor:
Mihaela Serpe, Kristi A. Wharton
Publikováno v:
Current Opinion in Genetics & Development. 23:374-384
Bone morphogenetic proteins (BMPs) are potent secreted signaling factors that trigger phosphorylation of Smad transcriptional regulators through receptor complex binding at the cell-surface. Resulting changes in target gene expression impact critical