Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Moroz Am"'
Publikováno v:
Molecular Biology. 47:236-241
We studied the frequency of occurrence and combinations of mutations in rpoB, katG, inhA, and oxyR-ahpC genes of Mycobacterium tuberculosis (MTB) DNA isolated from patients of Moscow region. In isoniazid monoresistant MTB isolates, Ser315Thr mutation
Publikováno v:
Молекулярная биология. 47:267-274
The frequency of mutations causing drug resistance in MTB isolates were studied in the respiratory material obtained from TB-patients in the Moscow Region. In izoniazid-resistant isolates, the most prevalent mutation was found to be the Ser315Thr sub
Publikováno v:
Journal of Antimicrobial Chemotherapy. 67:2107-2109
Kanamycin is an important second-line drug used to treat multidrug-resistant (MDR) tuberculosis (TB). Molecular analysis of the rrs gene seems to be not enough to identify every case of kanamycin resistance. In the present study we evaluated the inci
Autor:
Irtuganova Oa, Moroz Am, M A Vladimirskii, Mirzabekov Ad, V. M. Mikhailovich, Boris N. Strizhkov, Larisa Chernousova, Sergey A. Lapa, Vladislav V. Erokhin, Alexander Y. Sobolev, Dmitry A. Gryadunov, Shipina Lk, Skotnikova Oi, Litvinov Vi
Publikováno v:
Bulletin of Experimental Biology and Medicine. 131:94-98
Two alternative methods for identification of rifampicin-resistant strains of Mycobacterium tuberculosis on biological microchips are developed. The methods are based on detection of point mutations and other rearrangements in the rpoB gene region de
Publikováno v:
The Journal of antimicrobial chemotherapy. 68(10)
Objectives To determine critical concentrations of moxifloxacin and gatifloxacin for rapid evaluation of drug susceptibility of Mycobacterium tuberculosis in Middlebrook 7H9 broth using the automated system BACTEC™ MGIT™ 960. Methods In total we
Autor:
Skotnikova Oi, V. N. Krudu, V. M. Mikhailovich, Litvinov Vi, S. S. Ginda, Irtuganova Oa, O. V. Markova, E. Yu. Nosova, E. N. Strel'tsova, O. V. Kalyanina, M. N. Biryukova, Moroz Am, D. A. Gryadunov, Sergey A. Lapa, O. V. Golishcheva
Publikováno v:
Bulletin of Experimental Biology and Medicine. 136:273-275
Mutations in the rpoB, katG, inhA, oxyR/ahpC genes in rifampicin- and isoniazid-resistant M. tuberculosis strains isolated from residents of Moscow, Astrakhan', and Moldova Republic were studied by molecular biological methods (heteroduplex analysis,
Autor:
Alexander Y. Sobolev, E L Isaeva, Nadezhda Nikolaeva, E Y Nosova, Demkin Vv, Moroz Am, Skotnikova Oi, Litvinov Vi
Publikováno v:
Bulletin of Experimental Biology and Medicine. 129:612-614
A test-system based on amplification of IS 986 fragment (nested-PCR) was developed for the detection of Mycobacterium tuberculosis and M. bovis in different biological samples. We constructed external primers and selected appropriate amplifications p
Autor:
Skotnikova Oi, T. G. Smirnova, Moroz Am, Alexander S. Zasedatelev, Sergey A. Lapa, L. N. Chernousova, Dmitry A. Gryadunov, E. Yu. Nosova, O. V. Antonova, E. E. Larionova, A. V. Kuz’min, V. M. Mikhailovich
Publikováno v:
Bulletin of experimental biology and medicine. 145(1)
We developed a method of identification of Mycobacterium tuberculosis with simultaneous evaluation of the sensitivity to fluoroquinolones on a biological microchip array. The method of multiplex two-staged PCR followed by hybridization of a biochip m
Publikováno v:
Bulletin of experimental biology and medicine. 142(2)
Restriction fragment length polymorphism analysis of hsp65 gene was performed on museum strains of mycobacteria using Hin6I restrictase. Study of restriction profiles allowed us to distinguish mycobacterial species of the MAIS complex and several str
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