Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells

Autor: Morley, Sc, Sung, J, Sun, Gp, Martelli, Maria Paola, Bunnell, Sc, Bierer, Be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3982::d32397053c6301d482885371b5069087
http://hdl.handle.net/11391/153968

Novel coenzyme Q6 genetic variant increases susceptibility to pneumococcal disease.

Autor: Walker EC; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA.; Program in Immunology, Division of Biological and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO, USA., Javati S; Infection and Immunity Unit, Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea., Todd EM; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA., Matlam JP; Infection and Immunity Unit, Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea., Lin X; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA., Bryant M; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA., Krone E; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA., Ramani R; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA., Chandra P; Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA., Green TP; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA., Anaya EP; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA., Zhou JY; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA., Alexander KA; Department of Pediatrics, Division of Hematology-Oncology, Washington University School of Medicine, St. Louis, MO, USA., Tong RS; Department of Pediatrics, Division of Hematology-Oncology, Washington University School of Medicine, St. Louis, MO, USA., Yuasi L; Infection and Immunity Unit, Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea., Boluarte S; Department. of Pediatrics, Division of Critical Care Medicine, Washington University School of Medicine, St. Louis, MO, USA., Yang F; Department. of Pediatrics, Division of Critical Care Medicine, Washington University School of Medicine, St. Louis, MO, USA., Greenberg L; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA., Nerbonne JM; Departments of Developmental Biology and Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA., Greenberg MJ; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA., Clemens RA; Department. of Pediatrics, Division of Critical Care Medicine, Washington University School of Medicine, St. Louis, MO, USA., Philips JA; Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., Wilson LD; Division of Comparative Medicine, Research Animal Diagnostic Laboratory, Washington University School of Medicine, St. Louis, MO, USA., Halabi CM; Department of Pediatrics, Division of Nephrology and Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA., DeBosch BJ; Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pediatrics, Division of Gastroenterology, Hepatology & Nutrition, Indiana University School of Medicine, Indianapolis, IN, USA., Blyth CC; Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute and School of Medicine, University of Western Australia, Nedlands, Western Australia, Australia.; Department of Infectious Diseases, Perth Children's Hospital, Nedlands, Western Australia, Australia.; Department of Microbiology, PathWest Laboratory Medicine, QEII Medical Centre, Nedlands, Western Australia, Australia., Druley TE; Department of Pediatrics, Division of Hematology-Oncology, Washington University School of Medicine, St. Louis, MO, USA., Kazura JW; Center for Global Health & Diseases, School of Medicine, Case Western Reserve University, Cleveland, OH, USA., Pomat WS; Infection and Immunity Unit, Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea.; Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute and School of Medicine, University of Western Australia, Nedlands, Western Australia, Australia., Morley SC; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA. morleys@wustl.edu.; Program in Immunology, Division of Biological and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO, USA. morleys@wustl.edu.; Dept. of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. morleys@wustl.edu.

Publikováno v: Nature immunology [Nat Immunol] 2024 Nov 04. Date of Electronic Publication: 2024 Nov 04.

Expression of non-phosphorylatable S5A-L-plastin exerts phenotypes distinct from L-plastin deficiency during podosome formation and phagocytosis.

Autor: Lin X; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, United States., Krishnamoorthy P; Washington University Center for Cellular Imaging, Washington University School of Medicine, St. Louis, MO, United States., Walker EC; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, United States., Joshi H; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, United States., Morley SC; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, United States.; Department of Pathology and Immunology, Division of Immunobiology, Washington University School of Medicine, St. Louis, MO, United States.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2023 Apr 17; Vol. 11, pp. 1020091. Date of Electronic Publication: 2023 Apr 17 (Print Publication: 2023).

High-resolution imaging of protein secretion at the single-cell level using plasmon-enhanced FluoroDOT assay.

Autor: Seth A; Department of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.; Auragent Bioscience, LLC, St. Louis, MO 63108, USA., Mittal E; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63130, USA.; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63130, USA., Luan J; Department of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA., Kolla S; Department of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA., Mazer MB; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Joshi H; Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.; Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Gupta R; Department of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA., Rathi P; Department of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA., Wang Z; Department of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA., Morrissey JJ; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA., Ernst JD; Division of Experimental Medicine, University of California, San Francisco, San Francisco, CA 94110, USA., Portal-Celhay C; Division of Infectious Diseases, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA., Morley SC; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA., Philips JA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63130, USA.; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63130, USA., Singamaneni S; Department of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA.

Publikováno v: Cell reports methods [Cell Rep Methods] 2022 Aug 05; Vol. 2 (8), pp. 100267. Date of Electronic Publication: 2022 Aug 05 (Print Publication: 2022).

L-plastin enhances NLRP3 inflammasome assembly and bleomycin-induced lung fibrosis.

Autor: Joshi H; Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA; Division of Immunobiology, Department of Immunology and Pathology, Washington University School of Medicine, St. Louis, MO 63110, USA., Almgren-Bell A; Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA; Division of Immunobiology, Department of Immunology and Pathology, Washington University School of Medicine, St. Louis, MO 63110, USA., Anaya EP; Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA; Division of Immunobiology, Department of Immunology and Pathology, Washington University School of Medicine, St. Louis, MO 63110, USA., Todd EM; Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA; Division of Immunobiology, Department of Immunology and Pathology, Washington University School of Medicine, St. Louis, MO 63110, USA., Van Dyken SJ; Division of Immunobiology, Department of Immunology and Pathology, Washington University School of Medicine, St. Louis, MO 63110, USA., Seth A; Department of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA., McIntire KM; Division of Immunobiology, Department of Immunology and Pathology, Washington University School of Medicine, St. Louis, MO 63110, USA., Singamaneni S; Department of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA., Sutterwala F; Division of Infectious Diseases, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Morley SC; Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA; Division of Immunobiology, Department of Immunology and Pathology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: morleys@wustl.edu.

Publikováno v: Cell reports [Cell Rep] 2022 Mar 15; Vol. 38 (11), pp. 110507.